Integrin

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Catalog No.
Product Name
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Product Citation
  1. Integrin Inhibitor

    A-205804 is a potent and selective inhibitor of E-selectin and ICAM-1 with IC50 value of 20 nM and 25 nM, respectively.
  2. Integrin agonist

    Leukadherin 1 is an allosteric activator of CD11b/CD18. Increases CD11b/CD18-dependent cell adhesion to fibrinogen (EC50 = 4 μM).
  3. αvβ3 integrin inhibitor

    Cyclo (-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin.
  4. lpha-2-integrin inhibitor

    E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells.
  5. Inhibits integrin binding to RGD motifs

    RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
  6. Integrin Inhibitor

    TCS2314 is a integrin very late antigen-4 (VLA-4; α4β1) antagonist with IC50 value of 4.4 nM.
  7. GpIIb/IIIa antagonist

    GR 144053 trihydrochloride is a potent and selective platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist.
  8. glycoprotein IIb/IIIa antagonist

    Eptifibatide is a potent glycoprotein IIb/IIIa antagonist (GPIIb/IIIa; Kd = 120 nM) that inhibits platelet aggregation.
  9. α2β1 integrin inhibitor

    BTT-3033 is a α2β1 integrin inhibitor.
  10. α9β1/α4β1 integrin inhibitor

    BOP sodium salt is a novel dual alpha9beta1/alpha4beta1 integrin inhibitor.
  11. LFA-1 modulator

    BIRT-377 is a negative allosteric modulator of LFA-1.
  12. LFA-1 Antagonist

    BMS-688521 is a small molecule antagonist of leukocyte function associated antigen-1 (LFA-1).
  13. LFA-1 inhibitor

    RWJ 50271 is a selective inhibitor of LFA-1 (lymphocyte function-associated antigen-1).
  14. LFA-1/ICAM-1 interaction inhibitor

    A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction with IC50 valueof 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion, respectively.
  15. LFA-1 antagonist

    Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.
  16. integrin α5β1 antagonist

    ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist, which inhibits angiogenesis and growth of liver metastases in a murine model.
  17. α4 integrin receptor inhibitor

    Carotegrast is an orally available α4 integrin receptor inhibitor with anti-inflammatories activities.

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