Topoisomerase

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  1. Topoisomerase II inhibitor

    Amrubicin is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II. Antineoplastic.
  2. Topoisomerase II inhibitor

    Pixantrone is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.
  3. topoisomerase 1 inhibitor

    Genz-644282 is a non-camptothecin inhibitor of topoisomerase I with potential antineoplastic activity.
  4. Topo II inhibitor

    BNS-22 is a potent small molecule inhibitor of Topo II (IC50 2.8 M and 0.42 M for Topo II alpha and Topo II beta, respectively).
  5. DNA topoisomerase II inhibitor

    Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor.
  6. topoisomerase I/II inhibitor

    TAS 103, also known as BMS-247615, is a quinoline derivative that displays antitumor activity in murine and human tumor models
  7. Topoisomerase II inhibitor

    Voreloxin is a small molecule and a naphthyridine analogue with antineoplastic activity. Vosaroxin intercalates into DNA in a site-specific manner and blocks the re-ligation process carried out by topoisomerase II during DNA replication
  8. Topoisomerase inhibitor

    Voreloxin Hcl is a small molecule and a naphthyridine analogue with antineoplastic activity; inhibitor of Topo II.
  9. DNA Gyrase Inhibitor

    Clorobiocin is an aminocoumarin.
  10. Topoisomerase I inhibitor

    Belotecan, also known as CKD-602, is the semi-synthetic camptothecin analogue belotecan with potential antitumor activity.
  11. Top1 inhibitor

    Indotecan (LMP-400) is a potent topoisomerase 1(Top1) inhibitor with IC50 values of 300, 1200, 560 nM for P388, HCT116, MCF-7 cell lines, respectively.
  12. topoisomerase II inhibitor

    Gepotidacin (GSK2140944) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor.
  13. prodrug of the topoisomerase inhibitor Daunorubicin

    Daun02 is a prodrug of the topoisomerase inhibitor Daunorubicin.
  14. topoisomerase I inhibitor

    Topovale, also known as ARC-111, is a potent topoisomerase I inhibitor.

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