Total item
Cart Subtotal
$0.00 E3 ligase
7 Item(s)
per page
-
TAME
Catalog No. A10884 APC/C inhibitorTAME is a small molecule anaphase-promoting complex/cyclosome (APC) inhibitor with an IC50 of 12 μM. Learn More -
SMER-3
Catalog No. A13253 Ubiquitin E3 Ligase InhibitorSMER3 is a selective inhibitor of a yeast SCF family E3 ubiquitin ligase (SCFMet30) in vitro and in vivo. Induces the expression of MET genes; blocks cell proliferation. Learn More -
HLI-98C
Catalog No. A13654 Hdm2 ubiquitin ligase InhibitorHLI-98C, an analog, indeed inhibited Mdm2 E3 ligase activity. Learn More -
HLI 373
Catalog No. A15347 HDM2 inhibitorHLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) which blocks Hdm2-mediated ubiquitylation, proteasomal degradation of p53 and activates p53-dependent transcription. Learn More -
PRT 4165
Catalog No. A15453 Bmi1/Ring1A inhibitorPRT 4165 is an inhibitor of Bmi1/Ring1A, subunits of the polycomb repressive complex 1 (PRC1). It prevents Bmi1/Ring1A-mediated ubiquitination and drug-induced degradation of topoisomerase 2alpha. Learn More -
Thalidomide
Catalog No. A10924 E3 ubiquitin ligase inhibitorThalidomide can directly inhibit angiogenesis induced by bFGF or VEGF in vivo. Learn More -
Avadomide (CC-122)
Catalog No. A16854 E3 Ligase inhibitorAvadomide(CC-122), a new chemical entity termed pleiotropic pathway modifier, is a novel agent for Diffuse large B-cell lymphoma(DLBCL) with antitumor and immunomodulatory activity. Its molecular target is the protein cereblon (CRBN), a substrate receptor of the cullin ring E3 ubiquitin ligase complex CRL4CRBN. Learn More
7 Item(s)
per page
Adooq Quality Guarantee
We promise all products perform as described.