Guanylate Cyclase
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Olinciguat
Catalog No. A13670 guanylate cyclase (sGC) stimulatorOlinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay. Learn More -
Cinaciguat
Catalog No. A21283 sGC activatorCinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. Learn More -
NS-2028
Catalog No. A21643 sGC inhibitorNS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity. Learn More -
Riociguat (BAY 63-2521)
Catalog No. A11549 sGC stimulatorRiociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC). Learn More -
YC-1 (Lificiguat)
Catalog No. A12402 sGC activatorYC-1 is a direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide. Learn More -
Linaclotide
Catalog No. A13834 Guanylate cyclase C agonistLinaclotide is a peptide agonist of the guanylate cyclase 2C. Learn More -
BAY 41-2272
Catalog No. A15891 sGC activatorBAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. Learn More -
Vericiguat
Catalog No. A21031 guanylate cyclase stimulatorVericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. Learn More