Guanylate Cyclase

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  1. Olinciguat

    Catalog No. A13670
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    guanylate cyclase (sGC) stimulator
    Olinciguat (IW-1701) is an oral guanylate cyclase (sGC) stimulator with concentration-dependent stimulation of sGC in purified rat and human enzyme assays and a whole cell assay. Learn More
  2. Cinaciguat

    Catalog No. A21283
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    sGC activator
    Cinaciguat is an activator of guanylate cyclase (sGC), and used for acute decompensated heart failure. Learn More
  3. NS-2028

    Catalog No. A21643
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    sGC inhibitor
    NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor with IC50 values of 30 nM and 200 nM for basal and NO-stimulated enzyme activity. Learn More
  4. Riociguat (BAY 63-2521)

    Catalog No. A11549
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    sGC stimulator
    Riociguat (BAY 63-2521; BAY 632521) is a stimulator of soluble guanylate cyclase (sGC). Learn More
  5. YC-1 (Lificiguat)

    Catalog No. A12402
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    sGC activator
    YC-1 is a direct activator of soluble Guanylyl Cyclase (sGC), independent of Nitric Oxide. Learn More
  6. Linaclotide

    Catalog No. A13834
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    Guanylate cyclase C agonist
    Linaclotide is a peptide agonist of the guanylate cyclase 2C. Learn More
  7. BAY 41-2272

    Catalog No. A15891
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    sGC activator‎
    BAY 41-2272 is a direct and NO-independent soluble guanylate cyclase (sGC) stimulator. Learn More
  8. Vericiguat

    Catalog No. A21031
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    guanylate cyclase stimulator
    Vericiguat (BAY1021189) is a potent, orally available and soluble guanylate cyclase stimulator. Learn More

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