Total item
Cart Subtotal
$0.00 HMG-CoA Reductase
| Catalog No. | Inhibitor Name | HMG-CoA Reductase |
|---|---|---|
| A10810 | Rosuvastatin Calcium | ** |
| A11877 | Lovastatin | *** |
| A11912 | Pravastatin sodium | ** |
| A11184 | Clinofibrate | * |
| A11800 | Atorvastatin Calcium | |
| A13709 | Mevastatin |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
15 Item(s)
per page
-
Clinofibrate
Catalog No. A11184 HMG-CoA Reductase inhibitorClinofibrate is a lipid clearing agent that appears to modify lipid metabolism, diminishing the steroid induced accumulation of lipids within osteocytes. It also can effectively reduce the plasma fibrinogen level.
Learn More -
Rosuvastatin
Catalog No. A11122 HMG-CoA reductase inhibitorRosuvastatin is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Learn More -
2-Hydroxy atorvastatin calcium salt
Catalog No. A18971 HMG-CoA reductase inhibitor2-Hydroxy atorvastatin calcium salt is a hydroxy metabolite of Atorvastatin calcium salt. Atorvastatin is a potent HMG-CoA reductase inhibitor with an IC50 value of 8 nM. Learn More -
Simvastatin
Catalog No. A10845 HMG-CoA reductase inhibitorSimvastatin (MK 733) is a competitive inhibitor of HMG-CoA reductase with a Ki of 0.2 nM. Learn More -
Fluvastatin sodium
Catalog No. A10403 HMG-CoA reductase inhibitorFluvastatin sodium (XU 62320) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Learn More -
Fluvastatin
Catalog No. A21232 HMG-CoA reductase inhibitorFluvastatin (XU 62-320 free acid) is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM. Learn More -
Rosuvastatin calcium (Crestor)
Catalog No. A10810 HMG-CoA reductase inhibitorRosuvastatin (Crestor) is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins. Learn More -
Pravastatin sodium
Catalog No. A11912 HMG-CoA reductase inhibitorPravastatin sodium is a water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties. Learn More -
Atorvastatin calcium
Catalog No. A11800 HMG-CoA reductase inhibitorAtorvastatin (Lipitor) is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol. Learn More -
Pitavastatin calcium (Livalo)
Catalog No. A10737 HMG-CoA reductase inhibitorPitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis. Learn More -
Lovastatin (Mevacor)
Catalog No. A11877 HMG-CoA reductase inhibitorLovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent). Learn More -
Swertiamarin
Catalog No. A12128 HMG-CoA reductase inhibitorSwertiamarin has shown potential as antiatherogenic agent by inhibiting HMG-CoA reductase activity in high cholesterol fed rats. Learn More -
Mevastatin
Catalog No. A13709 HMG-CoA reductase inhibitorMevastatin is an inhibitor of HMG-CoA reductase. Learn More -
Atorvastatin
Catalog No. A13743 HMG-CoA reductase inhibitorAtorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective in treating hypercholesterolemia and certain dyslipidemias. Learn More -
Pitavastatin Lactone
Catalog No. A13896 HMG-CoA reductase inhibitorPitavastatin Lactone is an HMG-CoA reductase inhibitor. Learn More
15 Item(s)
per page
FILTER BY:
Shopping Options
- Actions
-
- Inhibitor (15)
- Target
Adooq Quality Guarantee
We promise all products perform as described.