Trusted by 10,000+ Scientists since 2006

HMG-CoA Reductase

Inhibitory Selectivity
Catalog No.Inhibitor Name HMG-CoA Reductase
A10810Rosuvastatin Calcium
A11912Pravastatin sodium
A11800Atorvastatin Calcium

1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

9 Item(s)

per page

Set Descending Direction
Catalog No. Product Name Application Product Information
A10810 SALE

Rosuvastatin calcium (Crestor)

HMG-CoA reductase inhibitor
Rosuvastatin (Crestor) is a member of the drug class of statins, used to treat high cholesterol and related conditions, and to prevent cardiovascular disease. Rosuvastatin is a competitive inhibitor of the enzyme HMG-CoA reductase, having a mechanism of action similar to that of other statins.
A11912 SALE

Pravastatin sodium

HMG-CoA reductase inhibitor
Pravastatin sodium is a water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (Ki~ 1 nM) and displays cardioprotective properties.
A11800 SALE

Atorvastatin calcium

HMG-CoA reductase inhibitor
Atorvastatin (Lipitor) is an inhibitor of HMG-CoA reductase used as a cholesterol-lowering medication that blocks the production of cholesterol.
A10737 SALE

Pitavastatin calcium (Livalo)

HMG-CoA reductase inhibitor
Pitavastatin Calcium is a competitive inhibitor of the enzyme HMGCR (HMG-CoA reductase) results in a reduction in LDL cholesterol synthesis.
A11877 SALE

Lovastatin (Mevacor)

HMG-CoA reductase inhibitor
Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM, used for lowering cholesterol (hypolipidemic agent).


HMG-CoA reductase inhibitor
Swertiamarin has shown potential as antiatherogenic agent by inhibiting HMG-CoA reductase activity in high cholesterol fed rats.
A13709 SALE


HMG-CoA reductase inhibitor
Mevastatin is an inhibitor of HMG-CoA reductase.
A13743 SALE


HMG-CoA reductase inhibitor
Atorvastatin is an HMG-CoA reductase inhibitor (IC50 = 154 nM) that is effective in treating hypercholesterolemia and certain dyslipidemias.

Pitavastatin Lactone

HMG-CoA reductase inhibitor
Pitavastatin Lactone is an HMG-CoA reductase inhibitor.

9 Item(s)

per page

Set Descending Direction