IL Receptor

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  1. IRAK inhibitor 3

    Catalog No. A11457
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    IL-1 receptor-associated kinase (IRAK) kinase modulator
    IRAK inhibitor 3 is an interleukin-1 (IL-I) receptor-associated kinase (IRAK) kinase modulator extracted from patent WO2008030579 A2. Learn More
  2. AF 12198

    Catalog No. A17213
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    IL-1 receptor antagonist
    AF 12198 is a potent and selective antagonist for the human type I interleukin-1 (IL-1) receptor. Learn More
  3. AS101

    Catalog No. A16414
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    IL-1 inhibitor
    AS101, a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme. Learn More
  4. APY0201

    Catalog No. A16268
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    IL-12/23 inhibitor
    APY0201 is a potent and selective IL-12/23 inhibitor. Learn More
  5. YM-90709

    Catalog No. A15999
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    interleukin-5 receptor antagonist
    YM-90709 is an interleukin-5 receptor antagonist. YM-90709 inhibits the binding of IL-5 to its receptor on peripheral human eosinophils and butyric acid-treated eosinophilic HL-60 clone 15 cells, with IC50 values of 1.0 and 0.57 microM, respectively. Learn More
  6. MCC950 sodium

    Catalog No. A13478
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    NLRP3 inhibitor
    MCC950 sodium is a potent NLRP3 inflammasome inhibitor that inhibits IL-1beta production with IC50 value of 7.5 nm. Learn More
  7. beta-Interleukin I (163-171), human

    Catalog No. A15426
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    T cell activator
    beta-Interleukin I (163-171), human, a peptide. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blood cells (leukocytes). Learn More
  8. Apilimod

    Catalog No. A13794
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    IL-12/IL-23 inhibitor
    Apilimod is a potent IL-12/IL-23 inhibitor, IL-12 production in cultures of IFN-r/LPS?Cstimulated human PBMCs is strongly inhibited by STA-5326 with an IC50 of 10 nM. Learn More
  9. SC-144

    Catalog No. A13660
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    gp130 inhibitor
    SC-144 is an orally active small-molecule gp130 inhibitor. Learn More
  10. Y320

    Catalog No. A11963
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    IL-17 inhibitor
    Y320 is an orally active immunomodulator, and inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 of 20 to 60 nM. Learn More
  11. Suplatast tosilate

    Catalog No. A10881
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    Suplatast Tosilate is a novel capsular anti-asthmatic agent that suppresses both IgE production, IL-4 and IL-5 synthesis with IC50 above 100 μM. Learn More

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