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P2X Receptor

P2X Receptor

Catalog No.	Product Name	Application	Product Information
A14983	A 438079 hydrochloride	P2X7 receptor antagonist	A 438079 Hcl is a competitive P2X7 receptor antagonist (pIC50 = 6.9 for the inhibition of Ca2+ influx in the human recombinant P2X7 cell line). P2X7 receptor
A11316 SALE	A 740003	P2X7 receptor antagonist	A 740003 is a novel competitive antagonist of P2X7 receptors (IC50 values = 40 nM for human and 18 nM for rat).
A12412	A-317491 sodium salt hydrate	P2X3 and P2X2/3 receptor antagonist	A-317491 sodium salt hydrate is a non-nucleotide P2X3 and P2X2/3 receptor antagonist, which inhibits calcium flux mediated by the receptors.
A16066 SALE	A-804598	P2X7 receptor antagonist	A-804598 is a P2X7 selective, competitive antagonist with the IC50s value for human, rat and mouse channels of 11, 10 and 9 nM, respectively.
A13131	AF-353	P2X3/P2X2/3 receptor antagonist	AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0).
A11107	GW791343 HCl	P2X7 modulator	GW791343 HCl acts as a negative allosteric modulator of human P2X7 (pIC50 = 6.9 - 7.2) and a positive allosteric modulator of rat P2X7.
A11473 SALE	KN-62	CaM kinase II inhibitor	KN-62 is a selective, cell-permeable inhibitor of CaM kinase I. CaMKII
A11972	NF 279	P2X1 antagonist	NF279 is a suramin analog that acts as a highly selective, competitive, and reversible ATP-antagonist of P2X receptor (IC50/KB ~ 1 ??M in smooth muscle).
A11690 SALE	Ticlopidine HCl	-	Ticlopidine is an adenosine diphosphate (ADP) receptor inhibitor. It inhibits platelet aggregation by altering the function of platelet membranes by blocking ADP receptors. This prevents the conformational change of glycoprotein IIb/IIIa which allows platelet binding to fibrinogen. P2 receptor