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Catalog No.
Product Name
Application
Product Information
Product Citation
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TNF-alpha inhibitor
Pomalidomide is a derivative of thalidomide and acts as an immunomodulator. -
E3 ubiquitin ligase inhibitor
Thalidomide can directly inhibit angiogenesis induced by bFGF or VEGF in vivo. -
RIPK1 inhibitor
Necrostatin-1 is an ATP-competitive, allosteric inhibitor of receptor-interacting protein kinase 1 (RIPK1) (EC50 = 182 nM). -
N-SMase inhibitor
GW4869 is a cell permeable, selective inhibitor of N-SMase (neutral sphingomyelinase).
- Guohao Wang, .et al. , Nat Commun, 2021, Sep 30;12(1):5733 PMID: 34593794
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NF-κB inhibitor
QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling. -
NGF inhibitor
Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds the NGF dimer (KD ~ 1 μM).
