Monocarboxylate transporters (MCT)

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  1. AR-C155858

    Catalog No. A11293
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    MCT1 and MCT2 inhibitor
    AR-C155858 is a potent inhibitor of monocarboxylate transporters MCT1 and MCT2 that binds to an intracellular site involving transmembrane helices 7-10. Learn More
  2. CHC

    Catalog No. A13372
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    MCT inhibitor
    CHC is a monocarboxylic acid transport (MCT) inhibitor. Exhibits antitumoral and antiangiogenic activity in gliomas; decreases glycolytic metabolism, migration, and invasion in U251 cells. Learn More
  3. AZD-3965

    Catalog No. A14186
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    MCT1 inhibitor
    AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM. Learn More
  4. AR-C117977

    Catalog No. A14360
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    MCT1 inhibitor
    AR-C117977 is a potent MCT1 inhibitor, which can reduce vimmune responses both in vitro and in vivo, maintains long-term graft survival, and induces operational tolerance. Learn More
  5. 7ACC2

    Catalog No. A15785
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    MCT inhibitor
    7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. Learn More
  6. 7ACC1

    Catalog No. A15810
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    MCT Inhibitor‎
    7ACC1 selectively interfere with lactate fluxes in the lactate-rich tumor microenvironment; inhibits lactate influx but not efflux in tumor cells expressing MCT1 and MCT4 transporters. Learn More
  7. UK 5099

    Catalog No. A13038
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    MCT Inhibitor
    UK 5099 is a potent inhibitor of plasma membrane monocarboxylate transporters (MCTs) and the mitochondrial pyruvate carrier (MPC); inhibits pyruvate-dependent O2 consumption with an IC50 of 50 nM. Learn More

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