NMDA Receptors

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  1. Flupirtine maleate

    Catalog No. A10251
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    NMDA antagonist
    Non-opioid analgesic with muscle relaxant properties. Learn More
  2. CGS19755

    Catalog No. A15791
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    NMDA antagonist
    CGS 19755 (cis-4-phosphonomethyl-2-piperidine carboxylic acid) was found to be a potent, stereospecific inhibitor of N-methyl-D-aspartate (NMDA)-evoked, but not KCl-evoked, [3H] acetylcholine release from slices of the rat striatum. Learn More
  3. Eliprodil

    Catalog No. A12946
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    NMDA antagonist
    Eliprodil is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). Learn More
  4. Rislenemdaz

    Catalog No. A21907
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    NMDA receptor GluN2B antagonist
    Rislenemdaz (CERC-301) is an orally bioavailable and selective N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B) antagonist with Ki and IC50 of 8.1 nM and 3.6 nM, respectively. Learn More
  5. Sarcosine

    Catalog No. A16692
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    GlyT inhibitor/NMDA receptor
    Sarcosine is a glycine transporter type 1 (GlyT) inhibitor and an N-methyl-D-aspartate (NMDA) receptor co-agonist at the glycine binding site. Learn More
  6. GV-196771A

    Catalog No. A13438
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    NMDA receptor antagonist
    GV-196771A is the sodium salt form of GV196771, is an NMDA receptor antagonist. Learn More
  7. RPR104632

    Catalog No. A13385
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    NMDA receptor antagonist
    RPR104632 is a specific antagonist of NMDA receptor, with potent neuroprotective properties. Learn More
  8. Ifenprodil tartrate

    Catalog No. A16583
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    NMDA receptor antagonist
    Ifenprodil tartrate is the atypical N-methyl-D-aspartate (NMDA) receptor antagonist, inhibits NMDA-induced currents at NR1A/NR2B receptors with high affinity (IC50 = 0.34 μM). Learn More
  9. Transcrocetinate disodium

    Catalog No. A21051
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    NMDA receptor antagonist
    Transcrocetinate disodium, extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity. Learn More
  10. MDL 105519

    Catalog No. A21192
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    NMDA receptor antagonist
    MDL 105519 is a potent and selective antagonist of glycine binding to the NMDA receptor. Learn More
  11. Radiprodil

    Catalog No. A21193
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    NMDA NR2B antagonist
    Radiprodil (RGH-896) is an orally active and selective NMDA NR2B antagonist. A potential therapeutic agent in treatment of neuropathic pain and possibly other chronic pain conditions. Learn More
  12. NMDA-IN-1

    Catalog No. A21419
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    NMDA antagonist
    NMDA-IN-1 is a potent and NR2B-selective NMDA antagonist with Ki of 0.85 nM. Learn More
  13. 7-Chlorokynurenic acid sodium salt

    Catalog No. A21879
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    NMDA receptor antagonist
    7-Chlorokynurenic acid sodium salt is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). Learn More
  14. SDZ 220-581 hydrochloride, SDZ220-581, SDZ-220-581

    Catalog No. A21897
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    NMDA receptor antagonist
    SDZ 220-581 hydrochloride is an orally active, potent, competitive NMDA receptor antagonist with pKi value of 7.7. Learn More
  15. (+)-MK 801 Maleate

    Catalog No. A12761
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    NMDA receptor antagonist
    (+)-MK 801 is a potent antagonist of NMDA with Ki value of 30.5nM. Learn More
  16. L-701324

    Catalog No. A15522
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    NMDA/glycine receptor antagonist
    L-701324 is an orally active and long acting anticonvulsant with high affinity and selectivity for the glycine site on the NMDA receptor, Learn More
  17. SDZ 220-581

    Catalog No. A12426
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    NMDA receptor antagonist
    SDZ 220-581 is a competitive NMDA receptor antagonist (pKi = 7.7). Learn More
  18. SDZ 220-581 Ammonium salt

    Catalog No. A15235
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    NMDA receptor antagonist
    SDZ 220-581 ammonium salt is a potent, competitive antagonist at the NMDA glutamate receptor subtype(pKi= 7.7). Learn More
  19. (-)-MK 801 maleate

    Catalog No. A13435
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    NMDA receptor antagonist.
    (-)-MK 801 maleate acts as a potent, selective, and non-competitive NMDA receptor antagonist. It acts by binding to a site located within the NMDA associated ion channel. Learn More
  20. DNQX

    Catalog No. A13882
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    NMDA receptor antagonist
    DNQX is a non-N-methyl-D-aspartate (non-NMDA) receptor complex antagonist. Learn More
  21. TCN 201

    Catalog No. A11947
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    NMDA Receptor Antagonist
    TCN 201 is a NMDA receptor antagonist selective for NR1/NR2A over NR1/NR2B-containing receptors Learn More
  22. NMDA

    Catalog No. A12751
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    NMDA receptor agonist
    NMDA is a prototypic NMDA receptor agonist. Learn More
  23. NVP-AAM077 Tetrasodium Hydrate (PEAQX)

    Catalog No. A14071
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    NMDA receptors antagonist
    NVP-AAM077 inhibited progenitor cells proliferation in the subventricular zone and dentate gyrus and reduced the survival of newborn cells in the dentate gyrus in the adult mice. Learn More
  24. MDL 29951

    Catalog No. A13729
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    NMDA receptor antagonist
    MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo. Learn More
  25. Felbamate

    Catalog No. A11862
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    Felbamate is an antagonist at the NMDA-associated glycine binding site. Learn More
  26. CIQ

    Catalog No. A15523
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    NMDA receptors Potentiator
    CIQ is a subunit-selective potentiator of NMDA receptors containing the NR2C or NR2D subunit. Learn More
  27. Orphenadrine citrate

    Catalog No. A11712
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    NMDA receptor antagonist
    Orphenadrine citrate is a NMDA receptor antagonist with Ki of 6.0 +/- 0.7 μM, HERG potassium channel blocker. Learn More
  28. Memantine hydrochloride

    Catalog No. A11708
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    NMDA receptor antagonist
    Memantine hydrochloride is an antagonist at the NMDA receptor, binding to the ion channel site. it was used in the treatment of Parkinsonism. Learn More
  29. ARL-15896

    Catalog No. A13858
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    NMDA receptor ion channel antagonist
    ARL-15896 is a novel N-methyl-D-aspartate receptor ion channel antagonist. Learn More
  30. GNE 0723

    Catalog No. A12757
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    NMDAR modulator
    GNE 0723 is a brain permeable positive allosteric modulator of NMDAR, with an EC50 of 21 nM for GluN2A, 7.4 and 6.2 μM for GluN2C and GluN2D, respectively. Learn More
  31. Ibotenic Acid

    Catalog No. A14006
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    NMDA& mGlu receptor agonist
    Ibotenic acid is a neuroexcitatory amino acid originally isolated from Amanita species that functions as a NMDA and metabotropic glutamate receptor agonist. Learn More
  32. GLYX-13 (Rapastinel)

    Catalog No. A13576
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    NMDAR modulator
    GLYX-13 is a selective weak partial agonist of the glycine site of the NMDA receptor which is under development by Naurex as adjunctive therapy for treatment-resistant depression. Learn More
  33. CNQX

    Catalog No. A16109
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    AMPA/kainate antagonist
    CNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 uM for AMPA and kainate receptors, respectively, versus IC50 = 25 uM for NMDA receptors). Learn More
  34. Ro 25-6981 maleate

    Catalog No. A13144
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    NMDA receptors Blocker
    Ro 25-6981 is a high-affinity, potent and selective blocker of N-methyl- D-aspartate (NMDA) receptors. Learn More
  35. 7CKA

    Catalog No. A17070
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    NMDA receptor antagonist
    7CKA is a NMDA receptor antagonist that acts at the glycine site. Learn More
  36. D-AP5

    Catalog No. A17044
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    NMDA antagonist
    D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist that competitively inhibits the glutamate binding site of NMDA receptors. Learn More
  37. Neu-2000

    Catalog No. A17033
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    NMDA receptor antagonist
    Neu-2000 is a NMDA receptor antagonist potentially for the treatment of stroke. Learn More
  38. Mephenesin

    Catalog No. A17493
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    NMDA receptor antagonist
    Mephenesin is an NMDA receptor antagonist, is a centrally acting muscle relaxant. Learn More
  39. Glycine

    Catalog No. A17936
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    NMDA antagonist
    AZD-4282, also known as aminoacetic acid and glycine, is a N-methyl-D-aspartate (NMDA) receptor antagonist potentially for the treatment of neuropathic pain. Learn More
  40. RO 25-6981 maleate

    Catalog No. A16083
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    NMDA receptors blocker
    Ro 25-6981 Maleate is a potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 uM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Learn More

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