Opioid Receptors

22 Item(s)

per page

Set Descending Direction
  1. TRV130 HCl (Oliceridine)

    Catalog No. A15444
    Quick View
    µ- opioid receptor agonist
    TRV 130 HCl is a novel μ-opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling(pEC50=8.1), with potency and efficacy similar to morphine, but with far less beta-arrestin recruitment and receptor internalization. Learn More
  2. LY2795050

    Catalog No. A15149
    Quick View
    k-opioid receptor antagonist
    LY2795050 is a novel selective κ-opioid Receptor (KOR) antagonist (IC50=0.72 nM) and has the potential as a PET tracer to image KOR in vivo. Learn More
  3. Methylnaltrexone Bromide

    Catalog No. A15159
    Quick View
    μ-opioid antagonist
    Methylnaltrexone Bromide is a pheriphally-acting µ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation. Learn More
  4. Eluxadoline

    Catalog No. A14085
    Quick View
    opioid receptor agonist
    Eluxadoline is a novel, orally-active drug approved for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). Learn More
  5. Alvimopan dihydrate

    Catalog No. A14991
    Quick View
    µ-opioid receptor agonist
    Alvimopan dihydrate(LY 246736, ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. Learn More
  6. Alvimopan monohydrate

    Catalog No. A14992
    Quick View
    µ-opioid receptor agonist
    Alvimopan monohydrate is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery. Learn More
  7. ADL5859 HCl

    Catalog No. A11072
    Quick View
    Opioid Receptor agonist
    ADL5859 HCl is a highly potent and selective δ opioid receptor agonist with Ki value to be 0.84 nM and ED50 value to be 20 nM. Learn More
  8. Naloxegol Oxalate

    Catalog No. A15972
    Quick View
    Opioid antagonist
    Naloxegol is a peripherally-selective opioid antagonist for the treatment of opioid-induced constipation. Learn More
  9. Docusate Sodium

    Catalog No. A16155
    Quick View
    Docusate Sodium is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally. Learn More
  10. Cebranopadol (GRT-6005)

    Catalog No. A12670
    Quick View
    Opioid Receptor Agonist
    Cebranopadol is a potent nociceptin/orphanin FQ peptide (NOP) and opioid receptor agonist Learn More
  11. ADL5747

    Catalog No. A13479
    Quick View
    δ opioid receptor agonist
    ADL5747 is a selective, nonpeptidic δ opioid receptor agonist. Learn More
  12. TRV130 (Oliceridine)

    Catalog No. A14337
    Quick View
    μ-opioid receptor agonist
    TRV130 is an opioid drug that is under evaluation in human clinical trials for the treatment of acute severe pain. TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less ??-arrestin 2 recruitment and receptor internalization, it displays less adverse effects than morphine. Learn More
  13. JTC-801

    Catalog No. A11076
    Quick View
    Opioid Receptor antagonist
    JTC-801 is a selective antagonist for the nociceptin receptor, also known as the ORL-1 receptor. Learn More
  14. MCOPPB 3HCl

    Catalog No. A10561
    Quick View
    NOP receptor agonist
    MCOPPB is a compound which acts as a potent and selective agonist for the nociceptin receptor, with a pKi of 10.07. Learn More
  15. BRL 52537 HCl

    Catalog No. A11210
    Quick View
    Opioid Receptors agonist
    BRL 52537 hydrochloride is a highly selective and potent κ-opioid agonist (Ki = 0.24 nM). 25 times more potent than morphine. Learn More
  16. Alvimopan (ADL 8-2698)

    Catalog No. A11292
    Quick View
    Opioid antagonist
    Alvimopan behaves as a peripherally acting μ-opioid antagonist. Alvimopan competitively binds to mu-opioid receptor in the gastrointestinal tract. Learn More
  17. BAN ORL 24

    Catalog No. A11322
    Quick View
    NOP antagonist
    BAN ORL 24 is a potent and selective NOP receptor antagonist. Learn More
  18. Trimebutine

    Catalog No. A11718
    Quick View
    Trimebutine is a drug with antimuscarinic and weak mu opioid agonist effects. Learn More
  19. Nalfurafine hydrochloride

    Catalog No. A12579
    Quick View
    opioid κ-selective agonist
    Nalfurafine hydrochloride is a kappa-opioid receptor agonist Learn More
  20. Nalmefene hydrochloride

    Catalog No. A13843
    Quick View
    dopamine receptor agonist
    Nalmefene hydrochloride is an opioid receptor antagonist. Learn More
  21. U-69593

    Catalog No. A14187
    Quick View
    κ1-opioid receptor agonist
    U-69593 is a potent, selective κ1-opioid receptor agonist (EC50 = 80-109 nM). Active in vivo. Antinociceptive. Learn More
  22. Bevenopran

    Catalog No. A17110
    Quick View
    opioid receptor antagonis
    Bevenopran, also known as CB-5945, ADL-5945, MK-2402, OpRA III, is a peripherally selective μ- and δ-opioid receptor antagonist. Learn More

22 Item(s)

per page

Set Descending Direction