Catalog No.Inhibitor Name P-gpOther
A10549Zosuquidar 3HCl
A12324Elacridar (GF120918)

1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Zosuquidar

    Catalog No. A15289
    P-gp inhibitor
    Zosuquidar is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Learn More
  2. Elacridar hydrochloride

    Catalog No. A15077
    P-gp inhibitor
    Elacridar hydrochloride is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. Learn More
  3. LY335979 (Zosuquidar 3HCl)

    Catalog No. A10549
    P-gp modulator
    LY335979 (Zosuquidar trihydrochloride) is a potent highly selective P-gp inhibitor. Learn More
  4. MC 70 HCl

    Catalog No. A16080
    P-gp inhibitor
    MC-70 is a potent P-gp inhibitor (EC50 = 0.69 uM). Learn More
  5. Biricodar (VX-710)

    Catalog No. A13533
    P-gp modulator
    Biricodar (VX-710) is a modulator of P-glycoprotein and MRP-1; shows effective chemosensitizing activity in multidrug resistant cells. Learn More
  6. Laniquidar

    Catalog No. A13532
    P-gp inhibitor
    Laniquidar is a third-generation P-gp inhibitor, which has been used in clinic trials for modulating multidrug resistance transporters. Learn More
  7. ONT-093

    Catalog No. A13531
    P-gp inhibitor
    ONT-093 is an orally bioavailable P-glycoprotein pump inhibitor, for the potential reversal of multidrug resistance in patients undergoing cancer chemotherapy. Learn More
  8. XR9576

    Catalog No. A13961
    P-glycoprotein inhibitor
    XR9576 is a P-glycoprotein inhibitor undergoing research as an adjuvant against multidrug resistance in cancer Learn More
  9. Cynarin

    Catalog No. A12004
    Cynarin is a phenolic compound found in artichoke. It has antioxidant and choleretic properties. It is a potential immunosuppressive agent. Learn More
  10. Tariquidar (XR9576)

    Catalog No. A11584
    P-gp inhibitor
    Tariquidar (XR9576) is a P-glycoprotein drug efflux pump inhibitor. Learn More
  11. Elacridar (GF120918)

    Catalog No. A12324
    P-gp & BCRP inhibitor
    Elacridaris a prototypical BCRP inhibitor which inhibits the Bcrp1-mediated transport. Learn More
  12. PSC-833 (Valspodar)

    Catalog No. A11080
    MDR1/P-gp Inhibitor
    PSC-833 is a kind of P-glycoprotein (P-gp) modulator that inhibits P-gp-mediated multidrug-resistance (MDR). Learn More
  13. KS-176

    Catalog No. A16195
    BCRP inhibitor
    KS-176 is a potent and selective inhibitor of the breast cancer resistance protein (BCRP) multidrug transporter (IC50 values are 0.59 and 1.39 uM in Pheo A and Hoechst 33342 assays respectively). Learn More

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