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LY315920 (Varespladib)
Catalog No. A10548 HnsPLA inhibitorLY315920 (Varespladib) is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2). Learn More -
Polydatin (Piceid)
Catalog No. A10741 PLA inhibitorPolydatin protects cerebral cells from ischemic damages via improvement of microcirculation and inhibition of platelet aggregation. In addition, polydatin inhibits ICAM-1 expression in endothelial cells stimulated by lipopolysaccharide; it also attenuates adhesion between white blood cells and endothelial cells. Learn More -
Quercetin (Sophoretin)
Catalog No. A10766 MAO-B inhibitorQuercetin inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Learn More -
Quercetin dihydrate (Sophoretin)
Catalog No. A10765 MAO-B inhibitorQuercetin inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Learn More -
Tanshinone I
Catalog No. A10889 Phospholipase inhibitorTanshinones are the major bioactive compounds of Salvia miltiorrhiza Bunge (Danshen) roots, which are used in many therapeutic remedies in Chinese traditional medicine. Learn More -
Chlorpromazine hydrochloride
Catalog No. A10206 Chlorpromazine is a dopamine antagonist of the typical antipsychotic class of medications possessing additional antiadrenergic, antiserotonergic, anticholinergic and antihistaminergic properties used to treat schizophrenia. Learn More -
Isotetrandrine
Catalog No. A13411 Isotetrandrine is a biscoclaurine alkaloid inhibitor of G protein activation of PLA2 but not PLC or PLD. Learn More -
FIPI
Catalog No. A13895 PLD inhibitorIsoforms of phospholipase D (PLD) cleave the head group from phospholipids, releasing the second messenger phosphatidic acid (PA), which can produce changes in Ras activation, cell spreading, stress fiber formation, chemotaxis, and membrane vesicle trafficking. FIPI is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM). Learn More -
Darapladib
Catalog No. A14274 Lp-PLA2 InhibitorDarapladib is a reversible lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor . Learn More -
U 73122
Catalog No. A14339 Phospholipase C inhibitorU 73122 is a phospholipase C inhibitor. It inhibits agonist-induced platelet aggregation with IC50 values of 1-5 uM. Learn More -
D609
Catalog No. A11388 PC-PLC inhibitorD609 is a selective competitive phosphatidyl choline-specific phospholipase C (PC-PLC) inhibitor (Ki = 6.4 μM); antiviral and antitumor agent. Learn More -
ML348
Catalog No. A16338 LYPLA1 inhibitorML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor (IC50 = 210 nM), Exhibits 14-fold selectivity for LYPLA1 over LYPLA2, Also selective over a panel of ~30 other serine hydrolases. Learn More -
Clofazimine
Catalog No. A16462 Clofazimine is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action include intercalation of clofazimine with bacterial DNA and increasing levels of cellular phospholipase A2. Learn More
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