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$0.00 DNA Methyltransferases
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Lomeguatrib
Catalog No. A12785 MGMT inhibitorLomeguatrib is a potent inhibitor of O6-alkylguanine-DNA-alkyltransferase. Learn More -
CM-272
Catalog No. A17173 G9a/DNMT inhibitorCM-272 is a reversible dual small molecule inhibitor against G9a and DNMTs in hematological malignancies. CAS: 1846570-31-7 (free base) 1846570-32-8 (TFA) Learn More -
CM-579
Catalog No. A18692 G9a/DNMT inhibitorCM-579 is a first-in-class reversible, dual inhibitor of G9a and DNMT, with IC50 values of 16 nM, 32 nM for G9a and DNMT, respectively. Has potent in vitro cellular activity in a wide range of cancer cells. Learn More -
6-Methyl-5-azacytidine
Catalog No. A13391 -
O6BTG-octylglucoside
Catalog No. A11432 MGMT inhibitorO6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor, with IC50s of 32 nM in vitro (cell extracts) and 10 nM in HeLa S3 cells. Learn More -
(-)-Epigallocatechin gallate
Catalog No. A10005 Antioxidant, antiangiogenic, antitumor agent(-)-Epigallocatechin gallate is a potent anti-oxidant polyphenol flavonoid isolated from green tea. Learn More -
Decitabine
Catalog No. A10292 DNA Methyltransferase InhibitorsDecitabine is a hypomethylating agent.It hypomethylates DNA by inhibiting DNA methyltransferase. Learn More -
Azacitidine(Vidaza)
Catalog No. A10105 DNMT inhibitorAzacitidine is a chemical analogue of the cytosine nucleoside used in DNA and RNA that is mainly used in the treatment of myelodysplastic syndrome (MDS). Learn More -
SGI-110 (Guadecitabine)
Catalog No. A12744 -
SGI 1027
Catalog No. A14120 DNMT inhibitorSGI 1027 is a DNMT inhibitor with IC50 of 6, 8, 7.5 uM for DNMT1, DNMT3A, and DNMT3B, respectively. Learn More -
Procainamide HCl
Catalog No. A14240 Sodium channel blocker/DNMT inhibitorProcainamide HCl is a sodium channel blocker, and also a DNA methyltransferase inhibitor. Learn More -
RG108
Catalog No. A13054 DNA methyltransferase inhibitorRG108 is a non-nucleoside inhibitor of DNA methyltransferase with IC50 of 115 nM. Learn More -
O6-Benzylguanine
Catalog No. A13706 MGMT inhibitorO6-Benzylguanine is an effective substrate and efficient inactivator of DNA alkyltransferase. O6-Benzylguanine is an inhibitor of MGMT. Learn More -
Nanaomycin A
Catalog No. A13477 DNMT3B inhibitorNanaomycin A is a selective inhibitor of DNA methyltransferase 3B (DNMT3B) with IC50 value of 500 nM. Learn More
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