MAO

Catalog No.Inhibitor Name MAO-AMAO-BMAOOther
A10818Safinamide Mesylate
*
****
A11722Rasagiline Mesylate
***
****
A11885Moclobemide
***
A10690Paeonol
*
**
A13358Tranylcypromine HCl
CYP2A6

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Rasagiline

    Catalog No. A11111
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    MAO B inhibitor
    Rasagiline is a selective irreversible inhibitor of MAO-B (monoamine oxidase-B). Learn More
  2. Iproniazid

    Catalog No. A17445
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    MAO inhibitor
    Iproniazid is a non-selective, irreversible monoamine oxidase (MAO) inhibitor (MAOI) that is used as an antidepressive agent. Learn More
  3. Molindone hydrochloride

    Catalog No. A17647
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    MAO inhibitor
    Molindone HCl is a D2 dopamine receptor antagonist. It also acts as a MAO inhibitor. Learn More
  4. Minaprine dihydrochloride

    Catalog No. A17722
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    MAO-A inhibitor
    Minaprine is a reversible inhibitor of MAO-A; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression. Learn More
  5. Toloxatone

    Catalog No. A18043
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    MAO-A inhibitor
    Toloxatone (MD 69276) is a reversible monoamine oxidase A (MAOA) inhibitor. Antidepressant. Learn More
  6. Iproniazid phosphate

    Catalog No. A18135
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    MAO inhibitor
    Iproniazid phosphate is an irreversible inhibitor of monoamine oxidase types A and B that is used as an antidepressive agent. It has also been used as an antitubercular agent, but its use is limited by its toxicity. Learn More
  7. TB5

    Catalog No. A13170
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    hMAO-B inhibitor
    TB5 is a potent, selective and reversible inhibitor of hMAO-B with a Ki value of 0.11??0.01 μM. Learn More
  8. CX-157

    Catalog No. A12200
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    MAO-A inhibitor
    CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3?ng/mL. Learn More
  9. Salsolidine

    Catalog No. A12969
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    MAO-A inhibitor
    Salsolidine is a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitive MAO A inhibitor. Learn More
  10. RS 8359

    Catalog No. A21240
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    MAO-A inhibitor
    RS 8359 is a selective and reversible MAO-A inhibitor, with antidepressant activity. Learn More
  11. Lazabemide

    Catalog No. A21270
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    MAO-B inhibitor
    Lazabemide(Ro 19-6327) is selective, reversible monoamine oxidase B (MAO-B) inhibitor (IC50 values are 0.03 and > 100 μM for MAO-B and MAO-A respectively). Learn More
  12. Ro 41-1049 hydrochloride

    Catalog No. A21672
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    inhibitor of monoamine oxidase-A (MAO-A)
    Ro 41-1049 hydrochloride is a reversible and selective inhibitor of monoamine oxidase-A (MAO-A). Learn More
  13. Brofaromine

    Catalog No. A21777
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    MAO inhibitor
    Brofaromine (CGP 11305A) is a monoamine oxidase (MAO) inhibitor with IC50 of 0.2?μM for MAO-A. Learn More
  14. Pargyline hydrochloride

    Catalog No. A17288
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    MAO inhibitor
    Pargyline hydrochloride is an irreversible inhibitor of monoamine oxidase (MAO) that is used clinically to treat moderate hypertension. Learn More
  15. Olodaterol

    Catalog No. A15761
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    MAO inhibitor
    Olodaterol is a long acting beta-adrenoceptor agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD), manufactured by Boehringer-Ingelheim. Learn More
  16. Hordenine

    Catalog No. A10454
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    MAO-B inhibitor
    Hordenine is a phenethylamine alkaloid with antibacterial and antibiotic properties. Learn More
  17. Quercetin (Sophoretin)

    Catalog No. A10766
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    MAO-B inhibitor
    Quercetin inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Learn More
  18. Quercetin dihydrate (Sophoretin)

    Catalog No. A10765
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    MAO-B inhibitor
    Quercetin inhibits many enzyme systems including tyrosine protein kinase, phospholipase A2, phosphodiesterases, mitochondrial ATPase, PI 3-kinase and protein kinase C. Learn More
  19. RN-1 2HCl

    Catalog No. A14344
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    MAO inhibitor
    RN-1 2HCl exhibits selectivity for LSD1 over monoamine oxidase (MAO)-A and MAO-B (IC50 values are 70 nM, 0.51 and 2.79 μM respectively, in a horseradish peroxidase-coupled assay). Learn More
  20. Rasagiline 13C3 mesylate racemic

    Catalog No. A21350
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    Monoamine oxidase inhibitor
    Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible inhibitor of monoamine oxidase. Learn More
  21. Safinamide Mesylate (FCE28073)

    Catalog No. A10818
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    MAO Inhibitor
    Safinamide Mesylate is mesylate salt of Safinamide, which selectively and reversibly inhibits MAO-B with IC50 of 0.45 μM. Learn More
  22. Isocarboxazid

    Catalog No. A17887
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    monoamine oxidase inhibitor
    Isocarboxazid is a non-selective and irreversible inhibitor of monoamine oxidase, with an IC50 of 4.8 μM for rat brain monoamine oxidase in vitro. Learn More
  23. Clorgyline hydrochloride

    Catalog No. A17357
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    monoamine oxidase A inhibitor
    Clorgyline hydrochloride is an irreversible and selective inhibitor of monoamine oxidase A (MAO-A) that is used in scientific research; structurally related to Pargyline. Learn More
  24. Rasagiline mesylate

    Catalog No. A11722
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    Monoamine oxidase inhibitor
    Rasagiline is an irreversible inhibitor of monoamine oxidase used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. It is selective for MAO type B over type A by a factor of fourteen. Learn More
  25. SL251188

    Catalog No. A11777
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    MAO-B Inhibitor
    SL-251188, an oxazolidinone derivative, was characterized in baboons as a radioligand for the in vivo visualization of MAO-B using positron emission tomography (PET). Learn More
  26. Moclobemide

    Catalog No. A11885
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    MAO Inhibitor
    Moclobemide is a reversible and selective inhibitor of monoamine oxidase A (MAO-A). Learn More
  27. Bifemelane HCl

    Catalog No. A13353
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    MAO Inhibitor
    Bifemelane hydrochloride is an antidepressant MAO inhibitor. Reverses catalepsy induced by tetrabenazine in mice and increases locomotor activity in MPTP-treated marmosets. Learn More
  28. Tranylcypromine hydrochloride

    Catalog No. A13358
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    LSD1/BHC110 & MAO inhibitor
    Tranylcypromine hydrochloride is a non-selective MAO-A/B inhibitor. Learn More
  29. Safinamide

    Catalog No. A13294
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    MAO-B inhibitor
    Safinamide is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. Learn More
  30. 2C-C HCl

    Catalog No. A14175
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    MAO inhibitor
    2C-C stimulates monoamine receptor activity and inhibits the re-uptake of serotonin and norepinephrine in rat brain synaptosomes (IC50 = 31 and 63 uM, respectively). Learn More
  31. 2C-I HCl

    Catalog No. A14176
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    MAO inhibitor
    Like other 2Cs, 2C-I (hydrochloride) is a monoamine oxidase inhibitor, blocking the breakdown of serotonin and norepinephrine (IC50 values of 79 and 37 uM, respectively), but not dopamine. Learn More
  32. PAT-1251 Hydrochloride

    Catalog No. A21969
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    LOXL2 inhibitor
    PAT-1251 Hydrochloride is a potent, selective and oral lysyl oxidase-like 2 (LOXL2) inhibitor, with IC50s of 0.71 and 1.17 μM for hLOXL2 and hLOXL3, respectively, and also potently inhibits mouse, rat, and dog LOXL2 (IC50s, 0.10, 0.12, and 0.16 μM, respectively). Learn More

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