Prostanoid Receptors
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Tafluprost
Catalog No. A17442 prostaglandin analogueTafluprost, also known as MK2452 and AFP-168, is a prostaglandin analogue used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. Learn More -
Treprostinil sodium
Catalog No. A21046 DP1/EP2 agonistTreprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6??0.1 and 6.2??1.2 nM, respectively. Learn More -
CJ-42794
Catalog No. A21948 EP4 antagonistCJ-42794 is a selective prostaglandin E receptor subtype 4 (EP4) antagonist, inhibits [3H]-PGE2 binding to the human EP4 receptor with a mean pKi of 8.5, a binding affinity that was at least 200-fold more selective for the human EP4 receptor than other human EP receptor subtypes (EP1, EP2, and EP3). Learn More -
AGN 210676
Catalog No. A21281 prostaglandin EP2 agonistAGN 210676 is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. Learn More -
Terutroban
Catalog No. A20884 thromboxane-prostaglandin receptor antagonistTerutroban is a thromboxane-prostaglandin receptor antagonist. Learn More -
MK-2894 sodium salt
Catalog No. A11498 EP4 antagonistMK-2894 sodium salt is a highly potent and selective second generation EP4 antagonist. Learn More -
(+)-Cloprostenol
Catalog No. A12979 prostaglandin F2α (PGF2α) analogue(+)-Cloprostenol is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor. Learn More -
ONO-AE3-208
Catalog No. A11516 EP4 antagonistONO-AE3-208 is an EP4 antagonist, and suppresses cell invasion, migration, and metastasis of prostate cancer. Learn More -
CAY10471 Racemate
Catalog No. A11760 Prostaglandin D2 receptor CRTH2 antagonistCAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist. Learn More -
Aligeron
Catalog No. A13241 prostaglandin (PG) antagonistAligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties. Learn More -
GSK726701A
Catalog No. A20101 EP4 partial agonistGSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4. Learn More -
Dinoprost tromethamine
Catalog No. A17505 Prostaglandin Receptor inhibitorDinoprost Tromethamine, also known as Dinoprost Trometamol, is a naturally occurring prostaglandin used in medicine to induce labor and as an abortifacient. Learn More -
Benorylate
Catalog No. A17501 Prostaglandin Receptor inhibitorBenorilate, also known as Win-11450, is an ester of aspirin and paracetamol with analgesic, antipyretic, and anti-inflammatory activity used in the treatment of rheumatoid diseases. Benorilate has less severe side effects than aspirin. Learn More -
GSK-269984A
Catalog No. A17096 -
Laropiprant (MK0524)
Catalog No. A11483 DP1 inhibitorLaropiprant is used in combination with niacin to reduce blood cholesterol. Laropiprant acts as a DP1 antagonist, reducing the vasodilation. Learn More -
Grapiprant (CJ-023423)
Catalog No. A15964 prostaglandin EP4 receptor antagonistGrapiprant is a novel, potent and selective prostaglandin EP4 receptor antagonist with antihyperalgesic properties. Learn More -
TG6-10-1
Catalog No. A15968 Prostaglandin E2 receptor antagonistTG6-10-1 is a potent and selective antagonist for the prostaglandin E2 receptor subtype EP2. Learn More -
KAG-308
Catalog No. A18389 EP4 agonistKAG-308, a newly-identified EP4-selective agonist shows efficacy for treating ulcerative colitis and can bring about lower risk of colorectal carcinogenesis by oral administration. Learn More -
CP544326 (Taprenepag)
Catalog No. A15853 EP2 AgonistC-544326 is a potent and selective prostaglandin E2 receptor agonist with EC50 value of 2.8 nM. Learn More -
PF-04418948
Catalog No. A12894 EP2 Receptor antagonistPF-04418948 is a potent and selective prostaglandin EP2 receptor antagonist with IC50 of 16 nM. Phase 1. Learn More -
MF498
Catalog No. A15532 EP4 receptor antagonistMF498 is a novel and selective E prostanoid receptor 4 (EP4 receptor) antagonist, displayed strong binding affinity for the EP4 receptor with Ki of 0.7 nM, Learn More -
GW627368
Catalog No. A15525 EP4 receptor antagonistGW627368 is a novel, potent and selective competitive antagonist of prostanoid EP4 receptor(Ki= 100 nM) with additional human TP receptor affinity(Ki= 150 nM). Learn More -
Saikosaponin B2
Catalog No. A14600 -
NS-304 (Selexipag)
Catalog No. A13880 prostacyclin receptor agonistNS-304 is a selective prostacyclin IP1 receptor agonist (Ki values are 260 and 2100 nM and for human and rat IP receptors, and >10 μM for EP1-4, DP, FP, and TP receptors). Learn More -
BAY-u 3405
Catalog No. A13751 dual antagonist of TP/DP2BAY-u 3405 is an approved human medication for the treatment of allergic rhinitis that has documented activity as an antagonist of the thromboxane receptor (TP receptor). Learn More -
Cloprostenol (sodium salt)
Catalog No. A13498 Cloprostenol is a synthetic analog of prostaglandin F2α (PGF2α). It is 200 times and 100 times more potent than PGF2α in terminating pregnancy in hamsters and rats, respectively, without the side effects associated with PGF2α. Learn More -
MK-2894
Catalog No. A11497 EP4 receptor antagonistMK-2894 is a highly potent and selective second generation EP4 antagonist. Learn More -
Ozagrel hydrochloride
Catalog No. A11742 Thromboxane A2 synthesis inhibitorOzagrel is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor. Learn More