Retinoid Receptor
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WYC-209
Catalog No. A19001 RAR agonistWYC-209, a synthetic retinoid, is a retinoic acid receptor (RAR) agonist. Learn More -
AC-55649
Catalog No. A20078 Human RARβ2 receptor agonistAC-55649 is a potent, highly isoform-selective agonist of human RARβ2 receptor, with a pEC50 of 6.9. Learn More -
LG 100268
Catalog No. A14127 RXR agonistLG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM). Learn More -
Etretinate
Catalog No. A16356 Etretinate is a second-generation retinoid to treat severe psoriasis; has been replaced by acitretin, a safer metabolite of etretinate. Learn More -
AGN 205728
Catalog No. A16296 RARγ antagonistAGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ. Learn More -
AGN 205327
Catalog No. A16295 RAR agonistAGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR. Learn More -
AGN 196996
Catalog No. A16294 RARα antagonistAGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). Learn More -
AGN 195183
Catalog No. A16293 RARα agonistAGN 195183 is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. Learn More -
AGN 194310
Catalog No. A16292 pan-RARs agonistAGN 194310 is a potent and selective pan-RARs agonist with Kd values of 3/2/5 nM for RARα/β/γ respectively. Learn More -
Tamibarotene
Catalog No. A11589 RARα agonistTamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Learn More -
Tretinoin
Catalog No. A10944 RAR agonistTretinoin is an endogenous agonist for retinoic acid receptors with IC50 value of 14 nM for RAR-alpha, RAR-beta and RAR-gamma receptors). Learn More -
Bexarotene (LGD1069)
Catalog No. A11094 Retinoid X Receptor LigandBexarotene is a highly selective retinoid X receptor (RXR) agonist. Learn More -
Fenretinide
Catalog No. A12163 RAR agonistFenretinide is a synthetic retinoid agonist. It is an antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Learn More -
TTNPB
Catalog No. A13007 RAR agonistTTNPB enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs). Learn More -
AR7
Catalog No. A12905 RARα antagonist.AR7 was developed as a highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RARα. Learn More -
Palovarotene
Catalog No. A12430 Palovarotene is a novel retinoic acid receptor gamma agonist for the treatment of emphysema Learn More -
Tazarotene
Catalog No. A10894 Tazarotene is a prodrug and a member of the acetylenic class of retinoids. Learn More -
CD 437
Catalog No. A11793 RARγ-selective agonistCD 437 is a synthetic retinoid that is an RARγ-selective agonist. Learn More -
AM 580
Catalog No. A11792 RARα agonistAM 580 is an analog of retinoic acid that acts as a selective RARα agonist. Learn More -
Adapalene
Catalog No. A10038 Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. Learn More -
Acitretin
Catalog No. A10035 Acitretin is a second generation retinoid and is typically used for psoriasis. Learn More -
Adarotene (ST1926)
Catalog No. A11298 Adarotene belongs to the so-called class of atypical retinoids. The presence of the phenolic hydroxyl group on Adarotene structure allows a rapid O-glucuronidation as a major mechanism of elimination of the drug, favoring a fast excretion of its glucuronide metabolite in the urines. Learn More