Retinoid Receptor

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  1. Bexarotene (LGD1069)

    Catalog No. A11094
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    Retinoid X Receptor Ligand
    Bexarotene is a highly selective retinoid X receptor (RXR) agonist. Learn More
  2. LG 100268

    Catalog No. A14127
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    RXR agonist
    LG 100268 is a potent RXR agonist for evaluation in the treatment of non-insulin-dependent (type II) diabetes mellitus (NIDDM). Learn More
  3. Tretinoin

    Catalog No. A10944
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    RAR agonist
    Tretinoin is an endogenous agonist for retinoic acid receptors with IC50 value of 14 nM for RAR-alpha, RAR-beta and RAR-gamma receptors). Learn More
  4. Tamibarotene

    Catalog No. A11589
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    RARα agonist
    Tamibarotene is a retinoic acid receptor α (RARα) agonist that induces differentiation (ED50 = 0.79 nM) and apoptosis of HL-60 cells in vitro. Learn More
  5. AGN 194310

    Catalog No. A16292
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    pan-RARs agonist
    AGN 194310 is a potent and selective pan-RARs agonist with Kd values of 3/2/5 nM for RARα/β/γ respectively. Learn More
  6. AGN 195183

    Catalog No. A16293
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    RARα agonist
    AGN 195183 is a potent and selective agonist of RARα (Kd=3 nM) with improved binding selectivity relative to AGN 193836; no activity on RARβ/γ. Learn More
  7. AGN 196996

    Catalog No. A16294
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    RARα antagonist
    AGN 196996 is a potent and selective RARα antagonist with Ki value of 2 nM; little binding affinity for RARβ(Ki=1087 nM) and RARγ(Ki=8523 nM). Learn More
  8. AGN 205327

    Catalog No. A16295
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    RAR agonist
    AGN 205327 is a potent synthetic RARs agonist with EC50 of 3766/734/32 nM for RARα/β/γ respectively; no inhibition on RXR. Learn More
  9. AGN 205728

    Catalog No. A16296
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    RARγ antagonist
    AGN 205728 is a potent and selective RARγ antagonist with Ki/IC95 values of 3 nM/ 0.6 nM; no inhibiton on RARα and RARβ. Learn More
  10. Fenretinide

    Catalog No. A12163
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    RAR agonist
    Fenretinide is a synthetic retinoid agonist. It is an antiproliferative, antioxidant and anticancer agent with a long half-life in vivo. Learn More
  11. TTNPB

    Catalog No. A13007
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    RAR agonist
    TTNPB enhances reprogramming efficiency in chemically induced pluripotent stem cells (CiPSCs). Learn More
  12. Adarotene (ST1926)

    Catalog No. A11298
    Adarotene belongs to the so-called class of atypical retinoids. The presence of the phenolic hydroxyl group on Adarotene structure allows a rapid O-glucuronidation as a major mechanism of elimination of the drug, favoring a fast excretion of its glucuronide metabolite in the urines. Learn More
  13. Acitretin

    Catalog No. A10035
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    Acitretin is a second generation retinoid and is typically used for psoriasis. Learn More
  14. Adapalene

    Catalog No. A10038
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    Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne and is also used (off-label) to treat keratosis pilaris as well as other skin conditions. Learn More
  15. AM 580

    Catalog No. A11792
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    RARα agonist
    AM 580 is an analog of retinoic acid that acts as a selective RARα agonist. Learn More
  16. CD 437

    Catalog No. A11793
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    RARγ-selective agonist
    CD 437 is a synthetic retinoid that is an RARγ-selective agonist. Learn More
  17. Tazarotene

    Catalog No. A10894
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    Tazarotene is a prodrug and a member of the acetylenic class of retinoids. Learn More
  18. Palovarotene

    Catalog No. A12430
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    Palovarotene is a novel retinoic acid receptor gamma agonist for the treatment of emphysema Learn More
  19. AR7

    Catalog No. A12905
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    RARα antagonist.
    AR7 was developed as a highly potent and selective enhancer of the chaperone-mediated autophagy (CMA) through antagonizing RARα. Learn More
  20. Etretinate

    Catalog No. A16356
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    Etretinate is a second-generation retinoid to treat severe psoriasis; has been replaced by acitretin, a safer metabolite of etretinate. Learn More

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