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Serine Protease
Inhibitory Selectivity
| Catalog No. | Inhibitor Name | Serine Protease | Other |
|---|---|---|---|
| A14263 | Aprotinin | *** | Thrombin,Trypsin,kallikrein |
| A12779 | Alvelestat (AZD9668) | **** | |
| A10617 | Nafamostat Mesylate | ||
| A11901 | PMSF | cysteine protease | |
| A14145 | Leupeptin Hemisulfate | Cysteine protease | |
| A14270 | AEBSF HCl |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
14 Item(s)
per page
| Catalog No. | Product Name | Application | Product Information |
|---|---|---|---|
A10617 SALE |
Nafamostat mesylate |
serine protease inhibitor |
Nafamostat is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma.
|
A11901 |
PMSF |
Serine/cysteine protease inhibitor |
PMSF is an irreversible serine/cysteine protease inhibitor.
|
A15315 |
SSR 69071
|
HLE inhibitor |
SSR 69071 is a high affinity, potent inhibitor of Neutrophil Elastase (human leukocyte elastase, HLE) (IC50 = 3.9 nM).
|
A13605 |
AAF-CMK |
Serine protease inhibitor |
AAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions1, and reversibly inhibits Cln2 (TPPI).
|
A14184 |
Sivelestat |
Neutrophil elastase inhibitor |
Sivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase).
|
A14263 SALE |
Aprotinin |
serine protease inhibitor |
Aprotinin is a small protein serine protease inhibitor, used to reduce perioperative blood loss and transfusion.
|
A14270 SALE |
AEBSF HCl |
serine protease inhibitor |
AEBSF HCl is a broad spectrum, irreversible serine protease inhibitor.
|
A14145 |
Leupeptin hemisulfate |
Cysteine Protease inhibitor |
Leupeptin hemisulfate is a reversible inhibitor of trypsin-like and cysteine proteases such as calpain.
|
A12779 SALE |
Alvelestat |
neutrophil elastase inhibitor |
Avelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE).
|
A14073 |
Sivelestat sodium salt |
Neutrophil elastase inhibitor |
Sivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro.
|
A11764 |
Camostat mesylate |
- |
Camostat mesylate is an orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin.
|
A11325 |
BCX 1470 methanesulfonate |
Serine protease inhibitor |
BCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro.
|
A11331 |
BCX 1470 |
Serine protease inhibitor |
BCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro.
|
A16137 |
Sivelestat sodium hydrate (ONO-5046 sodium hydrate) |
Neutrophil elastase inhibitor |
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse.
|
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