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$0.00 Serine Protease
| Catalog No. | Inhibitor Name | Serine Protease | Other |
|---|---|---|---|
| A14263 | Aprotinin | *** | Thrombin,Trypsin,kallikrein |
| A12779 | Alvelestat (AZD9668) | **** | |
| A10617 | Nafamostat Mesylate | ||
| A11901 | PMSF | cysteine protease | |
| A14145 | Leupeptin Hemisulfate | Cysteine protease | |
| A14270 | AEBSF HCl |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Upamostat
Catalog No. A21035 serine protease inhibitorUpamostat is a serine protease inhibitor. Upamostat is the orally available prodrug of the WX-UK1, which is a urokinase plasminogen activator (uPA) inhibitor. Learn More -
Nafamostat
Catalog No. A20827 serine protease inhibitorNafamostat is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Learn More -
Nafamostat hydrochloride
Catalog No. A20828 serine protease inhibitorNafamostat hydrochloride is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Learn More -
SPHINX31
Catalog No. A18640 Serine/arginin kinase 1 inhibitorSPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50 = 5.9 nM). Learn More -
AA26-9
Catalog No. A17158 serine hydrolase inhibitorAA26-9 is a potent and broad-spectrum serine hydrolase inhibitor. Learn More -
Fumonisin B1
Catalog No. A15379 serine/threonine phosphatase inhibitorFumonisin B1 is a fungal metabolite produced by Fusarium moniliforme, that has been shown to inhibit protein serine/threonine phosphatases (PP1, PP2A, PP2B, PP2C, and PP5/T/K/H), and is most effective with PP5. Learn More -
SSR 69071
Catalog No. A15315 HLE inhibitorSSR 69071 is a high affinity, potent inhibitor of Neutrophil Elastase (human leukocyte elastase, HLE) (IC50 = 3.9 nM). Learn More -
PMSF
Catalog No. A11901 Serine/cysteine protease inhibitorPMSF is an irreversible serine/cysteine protease inhibitor. Learn More -
Sivelestat sodium hydrate (ONO-5046 sodium hydrate)
Catalog No. A16137 Neutrophil elastase inhibitorSivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhibits leukocyte elastase obtained from rabbit, rat, hamster and mouse. Learn More -
AAF-CMK
Catalog No. A13605 Serine protease inhibitorAAF-CMK is a serine protease inhibitor which irreversibly inhibits TPPII (tripeptidyl peptidase II), a giant protease which may substitute for some proteasome functions1, and reversibly inhibits Cln2 (TPPI). Learn More -
Sivelestat
Catalog No. A14184 Neutrophil elastase inhibitorSivelestat is a cell-permeable sulfanilide compound that acts as a potent, substrate-competitive, and highly specific inhibitor of neutrophil elastase (IC50 = 19-49 nM in rat, rabbit, hamster, human, and mouse leukocyte elastase). Learn More -
BCX 1470
Catalog No. A11331 Serine protease inhibitorBCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro. Learn More -
BCX 1470 methanesulfonate
Catalog No. A11325 Serine protease inhibitorBCX 1470 is serine protease inhibitor. BCX 1470 blocks the esterolytic and hemolytic activities of the complement enzymes Cls and factor D in vitro. Learn More -
Camostat mesylate
Catalog No. A11764 Camostat mesylate is an orally active protease inhibitor. Known to inhibit trypsin and various inflammatory proteases including plasmin, kallikrein and thrombin. Learn More -
Sivelestat sodium salt
Catalog No. A14073 Neutrophil elastase inhibitorSivelestat sodium salt is a selective leukocyte elastase inhibitor (IC50 = 44 nM) that displays no activity at a range of other proteases. It inhibits NF-kB activation and LTB4-induced neutrophil transmigration in vitro. Learn More -
Alvelestat
Catalog No. A12779 neutrophil elastase inhibitorAvelestat, also known as AZD9668, is a novel, oral inhibitor of neutrophil elastase (NE). Learn More -
Leupeptin hemisulfate
Catalog No. A14145 Cysteine Protease inhibitorLeupeptin hemisulfate is a reversible inhibitor of trypsin-like and cysteine proteases such as calpain. Learn More -
AEBSF HCl
Catalog No. A14270 serine protease inhibitorAEBSF HCl is a broad spectrum, irreversible serine protease inhibitor. Learn More -
Aprotinin
Catalog No. A14263 serine protease inhibitorAprotinin is a small protein serine protease inhibitor, used to reduce perioperative blood loss and transfusion. Learn More -
Nafamostat mesylate
Catalog No. A10617 serine protease inhibitorNafamostat is an anticoagulant. Broad spectrum serine protease inhibitor. Reduces eosinophil infiltration, mast cell activation and airway responsiveness in a murine model of asthma. Learn More
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