TNF-α

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  1. Inducer (1)
  2. Inhibitor (3)


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Catalog No. Product Name Application Product Information
A11957

Bay 11-7821

E2 ubiquitin conjugating enzyme inhibitor
Bay 11-7821 is an irreversible inhibitor of TNF-α-stimulated IκBα phosphorylation.
A10522

Lenalidomide (CC-5013)

Ubiquitin ligase inducer
Lenalidomide is a derivative of thalidomide. In vitro, lenalidomide has three main activities: direct anti-tumor effect, inhibition of the micro environment support for tumor cells, and immunomodulatory role. It induces tumor cell apoptosis directly and indirectly by inhibition of bone marrow stromal cell support, by anti-angiogenic and anti-osteoclastogenic effects, and by immunomodulatory activity.
A10743

Pomalidomide (CC-4047)

TNF-alpha inhibitor
Pomalidomide is a derivative of thalidomide and acts as an immunomodulator.
A12748

QNZ

NF-κB inhibitor
QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling.

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