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Tezampanel
Catalog No. A15259 AMPA antagonistTezampanel is an antagonist at the AMPA and kainate families of ionotropic glutamate receptors, with selectivity for the GluR5 subtype of the kainate receptor. Learn More -
Fanapanel
Catalog No. A21200 AMPA/kainate antagonistFanapanel (ZK200775) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. Learn More -
PF-4778574
Catalog No. A21157 AMPA receptor positive allosteric modulatorPF-4778574 is a potent AMPA receptor positive allosteric modulator (PAM) that has been shown to enhance cognition in animal models. Learn More -
SYM2206
Catalog No. A20843 AMPA receptor antagonistSYM 2206 is a novel, potent, non-competitive AMPA receptor antagonist. Learn More -
JNJ-61432059
Catalog No. A20209 AMPAR negative modulatorJNJ-61432059 is an oral active and selective negative modulator of AMPAR associated with trans-membrane AMPAR regulatory protein (TARP) γ-8, with a pIC50 of 9.7 for GluA1/γ-8. Learn More -
(S)-(-)-5-Fluorowillardiine
Catalog No. A21337 AMPAR agonist(S)-(-)-5-Fluorowillardiine is a potent and specific AMPAR agonist. Learn More -
Naspm trihydrochloride
Catalog No. A21437 CP-AMPA receptors antagonistNaspm trihydrochloride (1-Naphthylacetyl spermine trihydrochloride), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. Learn More -
Fanapanel hydrate
Catalog No. A21668 AMPA/kainate antagonistFanapanel hydrate (ZK200775 hydrate) is a highly selective AMPA/kainate antagonist with little activity against NMDA; have Ki values of 3.2 nM, 100 nM, and 8.5 μM against quisqualate, kainate, and NMDA, respectively. Learn More -
CP 465022 hydrochloride
Catalog No. A13321 AMPA antagonistCP 465022 is a selective, non-competitive AMPA antagonist with IC50 of 25 nM in rat cortical neurons that displays potent anticonvulsant activity. Learn More -
Talampanel
Catalog No. A15515 AMPA/kainate receptor antagonistTalampanel is a non-competitive antagonist of AMPA-receptor. Learn More -
YM90K hydrochloride
Catalog No. A15495 AMPA antagonistYM90K hydrochloride is a selective AMPA receptor antagonist that delays neuronal death in a global ischemia model and cerebral infarction in a focal ischemia model following postischemic administration. Learn More -
Mibampator
Catalog No. A21717 AMPA receptors potentiatorMibampator (LY451395) is a potent and highly selective potentiator of the AMPA receptors. Learn More -
Philanthotoxin 74 dihydrochloride
Catalog No. A21739 AMPAR antagonistPhilanthotoxin 74 dihydrochloride (PhTx 74) is an AMPAR antagonist; inhibits GluR3 and GluR1 with IC50s of 263 and 296 nM, respectively. Learn More -
PEPA
Catalog No. A21904 AMPA receptors allosteric modulatorPEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. Learn More -
CMPDA
Catalog No. A21909 AMPA receptors positive allosteric modulatorCMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ?? 4.2 nM/63.4 ?? 5.6 nM for GluA2i/GluA2o receptor. Learn More -
Naspm
Catalog No. A21919 AMPA (CP-AMPA) receptors antagonistNaspm (1-Naphthyl acetyl spermine), a synthetic analogue of Joro spider toxin, is a calcium permeable AMPA (CP-AMPA) receptors antagonist. Learn More -
GYKI53655 Hydrochloride
Catalog No. A17032 AMPA antagonistGYKI53655 Hydrochloride is a non-competitive AMPA and kainate receptor antagonist. CAS: 143692-18-6 (Free Base); 143692-48-2 (HCl). Learn More -
CX546
Catalog No. A21923 positive AMPAR modulatorCX546 is a selective positive AMPAR modulator; the prototypical ampakine agent. Learn More -
CFM-2
Catalog No. A21930 non-competitive AMPAR antagonistCFM-2 is a selective non-competitive AMPAR antagonist. Learn More -
(S)-Willardiine
Catalog No. A21957 AMPA/kainate receptors agonist(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM. Learn More -
Becampanel
Catalog No. A21194 AMPA antagonistBecampanel (AMP397) is the first competitive AMPA antagonist and an antiepileptic agent. Learn More -
Aniracetam
Catalog No. A10078 AMPA Receptor InhibitorAniracetam is an ampakine and nootropic of the racetam chemical class purported to be considerably more potent than piracetam. Learn More -
CNQX disodium salt
Catalog No. A16110 AMPA/kainate antagonistCNQX disodium salt, water-soluble form of AMPA/kainate antagonist CNQX (GLXC-11053). Learn More -
CNQX
Catalog No. A16109 AMPA/kainate antagonistCNQX is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 uM for AMPA and kainate receptors, respectively, versus IC50 = 25 uM for NMDA receptors). Learn More -
Cyclothiazide
Catalog No. A13700 AMPA desensitization inhibitorCyclothiazide is a benzothiadiazide that acts as a potentiator of AMPA receptors, positively modulating its response to glutamic acid (EC50 = 3.8 M). Learn More -
Farampator
Catalog No. A13798 AMPA receptor modulatorFarampator has been investigated for its effect on AMPA receptors and researched for potential use in the treatment of schizophrenia and Alzheimer's Disease. It was found to improve short-term memory, but impaired episodic memory. Learn More -
IEM 1754 Dihydrobromide
Catalog No. A14010 AMPA Receptor BlockerIEM 1754 Dihydrobromide is a voltage-dependent open-channel blocker of AMPA receptors. Learn More -
DNQX
Catalog No. A13882 NMDA receptor antagonistDNQX is a non-N-methyl-D-aspartate (non-NMDA) receptor complex antagonist. Learn More -
NBQX
Catalog No. A13109 AMPA Receptor AntagonistNBQX is a potent, selective and competitive AMPA receptor antagonist. Learn More -
LY450108
Catalog No. A12425 LY450108 is an alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor potentiator. Learn More -
LY404187
Catalog No. A12424 LY404187 is a selective, potent and centrally active positive allosteric modulator of AMPA receptors. Learn More -
GYKI-52466 dihydrochloride
Catalog No. A10444 AMPA and Kainate antagonistGYKI-52466 dihydrochloride is selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Learn More -
Ampalex (CX-516)
Catalog No. A12349 Ampalex is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator Learn More
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