Cannabinoid Receptors

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  1. Taranabant ((1R,2R)stereoisomer)

    Catalog No. A21705
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    CB1 receptor inverse agonist
    Taranabant (1R,2R)stereoisomer is the R-enantiomer of Taranabant. Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist. Learn More
  2. VCE-004.8

    Catalog No. A18549
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    PPARγ and CB2 receptor dual agonist
    VCE-004.8, a semi-synthetic multitarget cannabinoquinoid, is a specific PPARγ and CB2 receptor dual agonist with potent anti-inflammatory activity. Learn More
  3. GNE-049

    Catalog No. A20206
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    CBP inhibitor
    GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively. Learn More
  4. SR 144528

    Catalog No. A12376
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    CB2 inverse agonist
    SR 144528 is a selective peripheral cannabinoid receptor inverse agonist that displays a Ki value of 0.6 nM for rat spleen and human recombinant CB2 receptors and a Ki value of 400 nM for rat brain and human recombinant CB1 receptors. Learn More
  5. CB1 antagonist 2

    Catalog No. A18810
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    CB1 antagonist
    CB1 antagonist 2 is caimabinoid 1 (CB1) antagonist extracted from patent WO2016184310A1, compound 3, inhibits CB1 in vivo with an IC50 of 25.5 nM. Learn More
  6. CB2R-IN-1

    Catalog No. A12306
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    cannabinoid CB2 receptor inverse agonist
    CB2R-IN-1 is a potent cannabinoid CB2 receptor inverse agonist with a Ki of 0.9 nM. Learn More
  7. Taranabant

    Catalog No. A11578
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    CB1 receptor inverse agonist
    Taranabant is a highly potent and selective cannabinoid 1 (CB1) receptor inverse agonist that inhibits the binding and functional activity of various agonists, with a binding Ki of 0.13 nM for the human CB1R in vitro. Learn More
  8. JD-5037

    Catalog No. A20837
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    CB1R antagonist
    JD-5037 is a novel, peripherally restricted CB1R antagonist with an IC50 of 1.5 nM. Learn More
  9. (±)-Ibipinabant

    Catalog No. A21439
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    CB-1 receptor antagonist
    (±)-Ibipinabant ((±)-SLV319) is the racemate of SLV319. (±)-Ibipinabant ((±)-SLV319) is a potent and selective cannabinoid-1 (CB-1) receptor antagonist with an IC50 of 22 nM. Learn More
  10. Taranabant racemate

    Catalog No. A21699
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    CB1 antagonist/inverse agonist
    Taranabant racemate is an antagonist and/or inverse agonist of the Cannabinoid-1 (CB1) receptor extracted from patent WO 2004048317 A1. Learn More
  11. Rimonabant hydrochloride

    Catalog No. A11548
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    CB1 receptor inverse agonist
    Rimonabant hydrochloride is a CB1 receptor inverse agonist. Learn More
  12. AM1241

    Catalog No. A16397
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    CB2 receptor agonist
    AM1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor. Learn More
  13. Bay 59-3074

    Catalog No. A16328
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    CB1/CB2 receptor agonist
    Bay 59-3074 is a novel, selective CB1/CB2 receptor partial agonist with Ki values of 48.3 and 45.5 nM at human CB1 and CB2 receptors respectively . Learn More
  14. AM630

    Catalog No. A14993
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    CB2 antagonist
    AM630 is a selectivity CB2 antagonist with Ki of 31.2 nM, > 150 fold selectivity over CB1 receptor. Learn More
  15. Otenabant

    Catalog No. A15200
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    CB1 receptor antagonist
    Otenabant is a recently discovered selective, high affinity, competitive CB1 receptor antagonist with Ki of 0.7 nM. Learn More
  16. WIN 55,212-2 mesylate

    Catalog No. A11932
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    CB receptor agonist
    WIN 55,212-2 is a potent cannabinoid receptor agonist that has been found to be a potent analgesic in a rat model of neuropathic pain. It activates p42 and p44 MAP kinase via receptor-mediated signaling. Learn More
  17. BML-190

    Catalog No. A11938
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    CB2 receptor ligand
    BML-190 is a selective inverse agonist of the human cannabinoid CB2 receptor. Learn More
  18. MDA 19

    Catalog No. A11939
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    CB2 agonist
    MDA 19 is a potent and selective agonist for the cannabinoid receptor CB2, with reasonable selectivity over the psychoactive CB1 receptor. Learn More
  19. CP 945598 HCl (Otenabant HCl)

    Catalog No. A11942
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    CB1 antagonist
    CP 945598 is a potent and highly selective CB1 antagonist. Learn More
  20. GW842166X

    Catalog No. A11253
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    CB2 receptor agonist
    GW842166X is a selective non-cannabinoid CB2 receptor agonist, which is undergoing clinical development as a novel oral treatment for inflammatory pain Learn More
  21. Rimonabant (SR141716)

    Catalog No. A11547
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    Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Learn More
  22. Org 27569

    Catalog No. A11513
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    CB1 modulator‎
    Org 27569 is a potent CB1 receptor allosteric modulator (pEC50 = 8.24). Learn More
  23. AM251

    Catalog No. A12914
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    CB1 receptor antagonist
    AM251 is a potent CB1 receptor antagonist (IC50 = 8 nM, Ki = 7.49 nM) that displays 306-fold selectivity over CB2 receptors. Learn More
  24. AM 2201

    Catalog No. A14174
    Cannabinoid inhibitor
    AM2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively Learn More
  25. Tedalinab

    Catalog No. A14189
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    CB2 receptor agonist
    Tedalinab (GRC-10693) is a drug developed for the treatment of osteoarthritis and neuropathic pain, which acts as a potent and selective cannabinoid CB2 receptor agonist. It has a very high selectivity of 4700x for CB2 over the related CB1 receptor, has good oral bioavailability and has shown promising safety results and effective analgesic and antiinflammatory actions in early clinical trials. Learn More
  26. PB-22

    Catalog No. A14110
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    PB-22 is an analog of JWH 018 which differs by having 8-hydroxyquinoline replacing the naphthalene group of JWH 018. Learn More
  27. UR-144

    Catalog No. A11096
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    UR-144 is a potent synthetic cannabinoid (CB) which preferentially binds the peripheral CB2 receptor (Ki = 1.8 nM) over the central CB1 receptor (Ki = 150 nM). Learn More

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