Dehydrogenases

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  1. Dehydrogenase inhibitor

    Mono-ammonium glycyrrhizinate(AMGZ) is a unique product derived from Licorice root and has an extremely sweet taste.
  2. dehydrogenase inhibitor

    Gossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.
  3. Dehydrogenase inhibitor

    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain.
  4. IMPDH inhibitor

    Mycophenolate mofetil is a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) in purine biosynthesis (specifically guanine synthesis) which is necessary for the growth of T cells and B cells.
  5. Dehydrogenase Inhibitor

    CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities.
  6. GAPDH inhibitor

    CGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor.
  7. Dihydroorotate Dehydrogenase Inhibitor

    Brequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis.
  8. DHODH inhibitor

    Vidofludimus is a novel orally active and potent DHODH inhibitor.
  9. DHODH inhibitor

    ML390 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor. ML390 is an inducer of myeloid differentiation and causes myeloid differentiation in murine (ER-HoxA9) and human (U937 and THP1) acute myeloid leukemia (AML) models.

  10. Dehydrogenase Inhibitor

    AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity.
  11. alcohol dehydrogenase inhibitor

    Fomepizole is an alcohol dehydrogenase inhibitor used for the treatment of ethylene glycol and methanol poisonings in adults.
  12. PHGDH inhibitor

    CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM.
  13. DHODH inhibitor

    DSM265 is a long-duration, potent and selective dihydroorotate dehydrogenase (DHODH)) inhibitor.
  14. PHGDH inhibitor

    NCT-503 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 value of 2.5 μM.
  15. Pyruvate dehydrogenase kinase inhibitor

    Sodium Dichloroacetate, also known as CPC-211; DCA; X-11S, is a Pyruvate dehydrogenase kinase inhibitor potentially for the treatment of myocardia ischemia, ischemic. Sodium dichloroacetate also exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3. Sodium dichloroacetate (DCA) reduces apoptosis in colorectal tumor hypoxia.
  16. PHGDH inhibitor

    NCT-502 is an inhibitor of human 3-phosphoglycerate dehydrogenase (PHGDH).
  17. ALDH2 inhibitor

    RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity. RV01 decreases iNOS expression, with anti-neuroinflammatory activity.
  18. dihydropyrimidine dehydrogenase inhibitor

    Eniluracil (5-Ethynyluracil), a uracil analogue and a mechanism-based irreversible inhibitor of dihydropyrimidine dehydrogenase (DPD), increases the oral bioavailability of 5-fluorouracil (5-FU) to 100%, facilitating uniform absorption and predictable toxicity.
  19. irreversible inhibitor of succinate dehydrogenase

    3-Nitropropanoic acid (β-Nitropropionic acid) is an irreversible inhibitor of succinate dehydrogenase. 3-Nitropropanoic acid exhibits potent antimycobacterial activity with a MIC value of 3.3 μM.
  20. 11β-HSD1 inhibitor

    BI-187004, also known as VTP-34072, is an 11β-hydroxysteroid dehydrogenase 1 inhibitor.
  21. 11β-HSD1 inhibitor

    BI-135585 is a potent and selective 11β-HSD1 inhibitor.

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