Hydroxylases

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  1. Nepicastat HCl

    Catalog No. A11172
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    DBH inhibitor

    Nepicastat hydrochloride is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.

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  2. Panaxtriol

    Catalog No. A14602
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    Tyrosine hydroxylase inducer
    Panaxtriol is a tyrosine hydroxylase inducer. Learn More
  3. LCI-699 (Osilodrostat)

    Catalog No. A14013
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    11β-hydroxylase inhibitor
    Osilodrostat (LCI699) is a potent inhibitor of human 11β-hydroxylase and aldosterone synthase with IC50 values of 2.5 and 0.7 nM, respectively. Learn More
  4. Collagen proline hydroxylase inhibitor

    Catalog No. A11371
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    Collagen proline hydroxylase inhibitor
    Collagen proline hydroxylase inhibitor is a collagen proline hydroxylase inhibitor. Learn More
  5. LP-533401

    Catalog No. A14325
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    Tph1 inhibitor
    LP-533401 is a small molecule inhibitor of Tph1. Learn More
  6. DMOG

    Catalog No. A13998
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    HIF-PH inhibitor
    DMOG is a cell permeable, competitive inhibitor of HIF-PH. It acts to stabilize HIF-1α expression at normal oxygen tensions in cultured cells, at concentrations between 0.1 and 1 mM. Learn More
  7. Metyrapone

    Catalog No. A13363
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    Cytochrome P450 inhibitor
  8. Ro 61-8048

    Catalog No. A12833
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    Hydroxylase Inhibitor
    Ro 61-8048 is a potent and competitive kynurenine 3-hydroxylase inhibitor (Ki = 4.8 nM, IC50 = 37 nM). Learn More
  9. Isotretinoin

    Catalog No. A10485
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    Isotretinoin was developed to be used as a chemotherapy medication for the treatment of brain cancer, pancreatic cancer and more. Learn More
  10. LX 1606 (Telotristat)

    Catalog No. A11785
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    Serotonin synthesis inhibitor
    LX 1606 is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Learn More
  11. Nepicastat (free base) (SYN-117)

    Catalog No. A10637
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    dopamine beta-hydroxylase inhibitor
    Nepicastat is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine. Learn More
  12. LX 1606 Hippurate

    Catalog No. A10542
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    Hydroxylase Inhibitor
    LX 1606 hippurate is an orally bioavailable, small-molecule, tryptophan hydroxylase (TPH) inhibitor with potential antiserotonergic activity. Learn More
  13. Tetrahydropapaverine HCl

    Catalog No. A10920
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    Hydroxylase inhibitor
    Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons. Learn More
  14. 4-Chloro-DL-phenylalanine

    Catalog No. A16424
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    Tryptophan hydroxylase inhibitor
    4-Chloro-DL-phenylalanine is a selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Learn More

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