Parasite

Artemether has been shown to have significant anticancer and antitumor activities. It is demonstrated that artemether caused strong inhibitory effects on brain glioma growth and angiogenesis in rats.

Metronidazole is a nitroimidazole antibiotic medication used particularly for anaerobic bacteria and protozoa.

Pyrantel pamoate is a deworming agent in the treatment of hookworms (all species) and roundworms in domesticated animal; acts as a depolarizing neuromuscular blocking agent.

Doramectin is an antiparasitic agent.

Toltrazuril sulfone is an antiprotozoal agent that acts upon Coccidia parasites.

AQ-13 dihydrochloride is an aminoquinoline antimalarial drug that is effective against chloroquine-resistant strains of Plasmodium falciparum.

Ferroquine is an ingenious antimalarial agent.

2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. It could be used in the preparation of 4??-methyl-2??-[(p-tolylsulfonyl) oxy] acetophenone.

Sulfaclozine (Sulfachloropyrazine) is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine is commonly used for the treatment of various poultry diseases (particularly, collibacteriosis, fowl cholera and coccidiosis).

Diethylcarbamazine citrate is an inhibitor of arachidonic acid metabolism in filarial microfilaria; is highly specific for several parasites and does not contain any toxic metallic elements.

Primaquine is the only generally available anti-malarial that prevents relapse in vivax and ovale malaria, and the only potent gametocytocide in falciparum malaria.

Sulfalene is an antimalarial agent.

Oxyclozanide is a salicylanilide anthelmintic that is a proton ionophore which uncouples oxidative phosphorylation of the target organism.

Sulfaquinoxaline sodium salt is an antibiotic which has activity against a broad spectrum of Gram-negative and Gram-positive bacteria.

Robenidine hydrochloride is an antibiotic used for the control of coccidiosis, a debilitating protozoal infection in poultry.

Quinine is a primary alkaloid of various species of Cinchona, optical isomer of Quinidine and an anti-malarial, skeletal, muscle relaxant.

Ethopabate is a folate metabolism inhibitor used in the prophylaxis and treatment of coccidiosis in chickens.

Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease.

Lumefantrine, also known as HSDB 7210, is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including infections acquired in chloroquine-resistant areas.

Artemotil (β-Arteether) has antimalarial activity for the treatment of chloroquine-resistant Plasmodium falciparum malaria with an IC50 of 1.61 nM. Artemotil also has central nervous system (CNS) neurotoxicity and anorectic toxicity in rats, dogs and monkeys.

Azamethiphos is an organothiophosphate insecticide. It is a veterinary drug used in Atlantic salmon fish farming to control parasites.

Febantel is an oral anthelmintic. It is a prodrug metabolised in vivo to fenbendazole. Febantel is used for the treatment and control of gastro-intestinal roundworms, lung worms and tapeworms.

Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.

Kojic Acid is a tyrosinase inhibitor. It is a chelation agent produced by several species of fungi, especially Aspergillus oryzae, which has the Japanese common name koji.

Oxantel Pamoate is an anthelmintic used to treat Trichuris trichiura infection.

L-(-)-Fucose is classified as a member of the hexoses, plays a role in A and B blood group antigen substructure determination, selectin-mediated leukocyte-endothelial adhesion, and host-microbe interactions.

Permethrin is a widely-used pesticide of the pyrethroid family.

Santonin is an Anthelmintic isolated from the dried unexpanded flower heads of Artemisia maritima and other species of Artemisia found principally in Russian and Chinese Turkestan and the Southern Ural region.

Asparagusic acid (1,2-dithiolane-4-carboxylic acid) is unique to asparagus. The compound is responsible for the odorous urine excreted after eating asparagus. Its derivatives ihydroasparagusic acid have anti-inflammatory effect.

Piperazine Citrate is an organic compound that consists of a six-membered ring, containting two nitrogen atoms at opposite positions in the ring; first introduced in 1953 as an Anthelmintic.

Buparvaquone is a hydroxynaphthoquinone antiprotozoal drug related to parvaquone and atovaquone.

Nilutamide (Nilandron) is a non-steroidal anti-androgen drug proposed in the treatment of metastatic prostatic carcinoma.

Carbendazim is a broad-spectrum benzimidazole fungicide which can be used to control a broad range of diseases on arable crops, fruits, vegetables, ornamentals and medicinal herbs.

Fexinidazole is a 5-nitroimidazole drug currently in clinical development for the treatment of human sleeping sickness (human African trypanosomiasis [HAT]), caused by infection with species of the protozoan parasite Trypanosoma brucei.

Naphthoquine phosphate is antimalarial drug.

Blasticidin S is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. Blasticidin S is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells.

Cycloguanil hydrochloride, the active metabolite of Proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.

Conoidin A is a cell permeable inhibitor of T. gondii enzyme peroxiredoxin II (TgPrxII).

Cepharanthine is an alkaloid derived from Stephania cepharantha Hayata, with possesses anti-inflammatory and antioxidative activities.

Tioxazafen is a disubstituted oxadiazole and a broad-spectrum seed treatment nematicide. Tioxazafen is designed to provide consistent broad-spectrum control of nematodes in corn, soy, and cotton.

Tizoxanide is the active metabolite of Nitazoxanide, which is a thiazolide anti-infective compound against anaerobic bacteria, protozoa, and a range of viruses. Tizoxanide has anti-HIV-1 activities.