Natural Products

Gynostemma Extract is a saponins extract derived from the Gynostemma pentaphyllum. The increase of SGOT, SGPT activities in CCl4 liver injury were significantly reduced by treatment with Gypenoside. It also elevated the A/G ratio.

Cynarin is a phenolic compound found in artichoke. It has antioxidant and choleretic properties. It is a potential immunosuppressive agent.

Agnuside is an known iridoid glycoside found in Vitex herbs or plants. Agnuside exhibits estrogen-like activities as it interacts with estrogen receptors (ER-alpha) and estrogen receptor-regulated pregesterone receptors.

Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor.

Apiin, a major flavonoid component of celery, shows antiinflammatory activity mediated through inhibition of nitric oxide synthesis and inhibition of iNOS expression.

Resibufogenin is a specific Na+/K+-ATPase inhibitor.

(-)-Catechin gallate is an antioxidant constituent of green tea. At uM concentrations, inhibits VEGF-induced tyrosine phosphorylation.

Chicoric acid is a caffeic acid derivative, belonging to the group of polypfenols. Chicoric acid is the most active compound in Echinacea pupurea. Chicoric acid is very stable in dry conditions but can be broken down by enzymes, which are found in the Echinacea, in moist conditions.

Chimaphilin is extracted from pyrola [Passiflora incarnata Fisch.] Chimaphilin could inhibit the viability of MCF-7 cells in a concentration-dependent manner, and the IC50 value was 43.30μM for 24h.

Cinobufagin is a specific Na+/K+-ATPase inhibitor. About as active as ouabain

Corosolic acid is a pentacyclic triterpene acid, found in Lagerstroemia speciosa, used in dietary supplements as a glucose-lowering agent and insulin mimetic.

Eriodictyol is a bitter-masking flavanone, a flavonoid extracted from Yerba Santa (Eriodictyon californicum), a plant native to North America.

gamma-Mangostin inhibits inhibitor-kappaB kinase activity and decreases lipopolysaccharide-induced cyclooxygenase-2 gene expression in C6 rat glioma cells.

Ginkgetin, a Biflavone from Ginko biloba leaves, inhibits cyclooxygenases-2 and 5-lipoxygenase in mouse bone marrow-derived mast cells.

Glycitein is an O-methylated isoflavone which accounts for 5-10% of the total isoflavones in soy food products.

Hypericin is a photosensitive antiviral, anticancer and antidepressant agent derived from Hypericum perforatum (St John's wort).

Isochlorogenic acid B is derived from the flowerbud of Lonicera japonica Thunb.

Isochlorogenic acid B is derived from the flowerbud of Lonicera japonica Thunb.

Isoorientin is derived from the herb of Pedicularis striata Pall.

isoquercitrin is derived from rutin (quercetin-3-O-rhamnoglucoside), which is treated with acid to obtain quercetin. Rutin is isolated from the seed pods of the Brazilian shrub ??fava d?anta?? (Dimorphandra mollis). There is significant evidence in the literature concerning anti-proliferative and cell growth regulating properties of quercetin.

Isosteviol has beneficial effects on palmitate-induced alpha-cell dysfunction and gene expression.

Isovitexin (or homovitexin, saponaretin) is a flavone. the apigenin-6-C-glucoside. It can be found in the passion flower and the a?a?? palm.

Jaceosidin is a pharmacologically active flavone derived from Artemisia argyi, inhibits phorbol-ester-induced upregulation of COX-2 and MMP-9 by blocking phosphorylation of ERK-1 and -2 in cultured human mammary epithelial cells.

Mangiferin has been shown to have the effect of improving dyslipidemia.

Mogroside IV, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.

Neochlorogenic acid is a natural polyphenolic compound found in some types dried fruits and a variety of other plant sources such as peach

Niranthin is a lignan isolated from the aerial parts of the plant Phyllanthus amarus, exhibits a wide spectrum of pharmacological activities.

Procyanidin b2 inhibits human aortic smooth muscle cell proliferation and migration induced by advanced glycation end products.

Punicalin is a highly active carbonic anhydrase inhibitor.

Quercitrin is known as an bio flavonoid antioxidant and was investigated extensively in its antioxidant potential in streptrozotocin (STZ)-induced diabetic rats.

Sesamolin is a lignan isolated from sesame oil. It is found that sesamolin inhibited lipid peroxidation in rat liver and kidney.

Triptonide is a Triptolide analogue used in the preparation of cytotoxic fluorinated Triptolide.

Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro.

Chelidonin inhibits tubulin polymerisation (IC50=24 uM), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest.

Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, inhibits NO release, with anti-fibrotic activity.

Cyanidin chloride is an anthocyanin polyphenolic antioxidant compound with demonstrated cell protectant effects.

Spinosin, a C-glycoside flavonoid from semen Zizhiphi Spinozae, potentiated pentobarbital-induced sleep via the serotonergic system.

Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz, has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases.

Eugenin is a chromone isolated from Peucedanum japonicum, with potent antiplatelet aggregation activity.

Manool is a labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13. It has a role as an antineoplastic agent, a plant metabolite and an antibacterial agent. It is a labdane diterpenoid and a tertiary alcohol.

Harringtonin is an alkaloid isolated from Cephalotaxus harringtonia, and an antitumor agent.

Silibinin has also demonstrated in vitro anti-cancer effects against human prostate adenocarcinoma cells, estrogen-dependent and -independent human breast carcinoma cells, human ectocervical carcinoma cells, human colon cancer cells, and both small and nonsmall human lung carcinoma cells.

Clobetasol is a topical corticosteroid, glucocorticoid, and antiinflammatory.

Meisoindigo, a derivative of Indigo naturalis, is a promising agent with in vitro and in vivo activity against human acute myeloid leukemia.

Dynemicin A is an antitumor natural product isolated from Micromonospora chersina which causes DNA strand cleavage.

Psoralen is a CovA photochemical probe in studies of DNA mutation and repair mechanisms.

Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.

Fraxinellone is an insecticidal agent, inhibiting growth of larvae, used in the treatment and protection of crops and produce. Also, a naturally occurring compound used in the treatment of tumors.

Diacetylkorseveriline is an antiarrhythmic (classes i and iv)? belonging to a novel structural class. effective against arrhythmia caused by aconitine? cacl2? electric stimulation of the ventricles or ligature of the aorta, recommended dose for one cycle of experiment on mice: 3.0-30.0 mg/kg? intravenously.

Delsoline is a nicotinic receptor antagonist, ganglion blocker, exhibits weak affinity at brain ??-bungarotoxin-sensitive nicotinic acetylcholine receptors.