Protein Kinase A (PKA)

17 Item(s)

per page

Set Descending Direction
  1. A-3 Hydrochloride

    Catalog No. A13584
    Quick View
    PKA, PKG, Casein Kinase I and II inhibitor
    A-3 Hydrochloride is an inhibitor of PKA (cAMP-dependent protein kinase, Ki=4.3μM) and cGMP-dependent protein kinase, Ki=3.8μM, PKC (protein kinase C, Ki=47μM), casein kinase I and II, and MLCK (myosin light chain kinase) ( Ki=7.4μM). Learn More
  2. PKA inhibitor fragment (6-22) amide

    Catalog No. A14868
    Quick View
    PKA inhibitor
    PKA inhibitor fragment (6-22) amide is a synthetic peptide that acts as a protein kinase inhibitor. Learn More
  3. cAMPS-Rp, triethylammonium salt

    Catalog No. A16028
    Quick View
    reversible PKA inhibitor
    Rp-cAMPS is a cell-permeable and reversible inhibitor of PKA (protein kinase A) (Ki = 11 uM). Rp-cAMPS is resistant to hydrolysis by phosphodiesterases and is noncompetitive with respect to ATP. Learn More
  4. 6-Bnz-cAMP sodium salt

    Catalog No. A16017
    Quick View
    PKA-selective activator
    6-Bnz-cAMP is a PKA-selective activator. It regulates the PKA dependent signaling pathways. Learn More
  5. Dibutyryl-cAMP

    Catalog No. A15914
    Quick View
    PKA activator
    Dibutyryl-cAMP is a cell-permeable PKA activator by mimicing the action of endogenous cAMP. Learn More
  6. 8-Bromo-cAMP

    Catalog No. A15910
    Quick View
    protein kinase A activator
    8-Bromo-cAMP is a cell perbeable cyclic AMP (cAMP) analog and a PKA activator. Learn More
  7. Synaptamide

    Catalog No. A16222
    Quick View
    Synaptamide is a potent mediator for neurogenic differentiation of NSCs acting through PKA/CREB activation. Learn More
  8. CCG215022

    Catalog No. A16189
    Quick View
    GRK2/5 inhibitor
    CCG215022 is a potent GRK2 and GRK5 inhibitor. CCG215022 exhibited nanomolar IC50 values against both GRK2 and GRK5 and good selectivity against other closely related kinases such as GRK1 and PKA. Learn More
  9. cGMP Dependent Kinase Inhibitor Peptid

    Catalog No. A16052
    Quick View
    PKG/PKA inhibitor
    cGMP Dependent Kinase Inhibitor Peptid is a specific cGKI (cyclic GMP-dependent protein kinase) inhibitor. Data indicates that it does not block cyclic GMP-dependent protein kinase phosphorylation of intact histones and has been used to study Plasmodium falciparum. Learn More
  10. PKI 14-22 amide, myristoylated

    Catalog No. A16031
    Quick View
    PKA inhibitor
    PKI 14-22 amide, myristoylated is a useful heat stable cAMP-dependent protein kinase inhibitor. This is often used to study PKA in cellular systems in-vitro. Learn More
  11. KT 5720

    Catalog No. A16016
    Quick View
    PKA inhibitor
    KT 5720 is prepared by a modificiation of K-252a (sc-200517), which is synthesized by the fungus Nocardiopsis sp. Learn More
  12. A-674563

    Catalog No. A11034
    Quick View
    Akt inhibitor
    A-674563 is a B/Akt inhibitor with an IC50 of 14 nM and also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respectively. Learn More
  13. AT7867 2HCl

    Catalog No. A15006
    Quick View
    Akt inhibitor
    AT7867 dihydrochloride is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively, little activity outside the AGC kinase family. Learn More
  14. NH125

    Catalog No. A14307
    Quick View
    eEF-2 inhibitor
    NH125 is a selective eEF-2 kinase inhibitor. Learn More
  15. AT13148

    Catalog No. A12464
    Quick View
    multi-AGC kinase inhibitor
    AT13148 is a novel oral multi-AGC kinase inhibitor with potent pharmacodynamic and antitumor activity, which shows a distinct mechanism of action from other AKT inhibitors. Learn More
  16. H 89 2HCl

    Catalog No. A11935
    Quick View
    PKA inhibitor
    H 89 dihydrochloride is a cell-permeable, selective, reversible, ATP-competitive and potent inhibitor of protein kinase. Learn More
  17. Daphnetin

    Catalog No. A10286
    Quick View
    EGFR, PKA,PKC inhibitor
    Daphnetin is a coumarin analog that acts as an inhibitor of several protein kinases. It inhibits EGFR kinase (IC50 = 7.67 µM), PKA (IC50 = 9.33 µM), and PKC (IC50 = 25 µM), in vitro. The inhibition of EGFR kinase by daphnetin was competitive to ATP and non-competitive to the peptide substrate. Also acts as a potent antioxidant and anti-malarial agent. Learn More

17 Item(s)

per page

Set Descending Direction
Rewards