RNA/DNA Polymerase

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  1. Tenofovir (Viread)

    Catalog No. A10908
    HIV reverse transcriptase inhibitor
    Tenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Learn More
  2. Thiolutin

    Catalog No. A15386
    RNA polymerase Inhibitor
    Thiolutin is an RNA polymerase inhibitor, and a sulfur-based microbial antibiotic generated by Streptomyces sp. Learn More
  3. Mithramycin A

    Catalog No. A15385
    DNA/RNA polymerase Inhibitor
    Mithramycin A is an antibiotic DNA/RNA polymerase and DNA binding transcriptional inhibitor observed to facilitate TNF-?? and Fas-ligand induced apoptosis. Learn More
  4. Oncrasin 1

    Catalog No. A15333
    RNA polymerase II inhibitor
    Oncrasin 1 is a proapoptotic substance. Induces abnormal nuclear aggregation of PKCι and suppressing RNA transcription. Learn More
  5. Valaciclovir

    Catalog No. A15270
    DNA polymerase Inhibitor
    Valacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Learn More
  6. BMH-21

    Catalog No. A14335
    RNA polymerase inhibitor
    BMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. Learn More
  7. Delavirdine mesylate

    Catalog No. A13274
    NNRT inhibitor
    Delavirdine is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Learn More
  8. Actinomycin D

    Catalog No. A13239
    Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria. Learn More
  9. T-705 (Favipiravir)

    Catalog No. A11590
    viral RNA polymerase inhibitor
    T-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo. Learn More
  10. Rifampin

    Catalog No. A10791
    RNA polymerase inhibitor
    Antibiotic; inhibits bacterial RNA polymerase. Prototypical activator of the pregnane X receptor (PXR). Learn More
  11. Rifabutin

    Catalog No. A10790
    RNA polymerase inhibitor
    Rifabutin is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria. Learn More
  12. Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells. Learn More
  13. Abacavir

    Catalog No. A11115
    Transcriptase inhibitor
    Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More
  14. Abacavir sulfate

    Catalog No. A11120
    Transcriptase inhibitor
    Abacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More
  15. Triptolide (PG490)

    Catalog No. A11596
    Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. Learn More

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