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Dehydroaltenusin
Catalog No. A21804 eukaryotic DNA polymerase α inhibitorDehydroaltenusin is a small molecule selective inhibitor of eukaryotic DNA polymerase α, a type of antibiotic produced by a fungus with an IC50 value of 0.68 μM. Learn More -
Rifabutin
Catalog No. A10790 RNA polymerase inhibitorRifabutin is a bactericidal antibiotic drug primarily used in the treatment of tuberculosis. Its effect is based on blocking the DNA-dependent RNA-polymerase of the bacteria. Learn More -
Rifampin
Catalog No. A10791 RNA polymerase inhibitorAntibiotic; inhibits bacterial RNA polymerase. Prototypical activator of the pregnane X receptor (PXR). Learn More -
T-705 (Favipiravir)
Catalog No. A11590 viral RNA polymerase inhibitorT-705, a substituted pyrazine compound, has been found to exhibit potent anti-influenza virus activity in vitro and in vivo.
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Actinomycin D
Catalog No. A13239 Actinomycin D is a metabolite isolated from Streptomyces parvulus that binds to the GpC steps of DNA. The compound acts as an antibiotic and is more effective against gram-positive bacteria than gram negative bacteria. Learn More -
Valaciclovir
Catalog No. A15270 DNA polymerase InhibitorValacyclovir is an antiviral drug used in the management of herpes simplex, herpes zoster, and herpes B. Learn More -
dmDNA31
Catalog No. A18469 DNA-dependent RNA polymerase inhibitordmDNA31 is a rifamycin-class antibiotic that inhibits bacterial DNA-dependent RNA polymerase with potent bactericidal activity against S. aureus. Learn More -
ddATP
Catalog No. A18898 DNA polymerase inhibitordATP is a dideoxynucleotide, acts as a chain-elongating inhibitor of DNA polymerase, used for Sanger method for DNA sequencing. Learn More -
DNA31
Catalog No. A18466 -
Pseudouridimycin
Catalog No. A18520 RNA polymerase inhibitorPseudouridimycin (PUM), an antibiotic, is a selective bacterial RNA polymerase (RNAP) inhibitor. Pseudouridimycin is a C-nucleoside analogue that is effective against both Gram-negative and Gram-positive bacteria. Learn More -
ACX-362E
Catalog No. A18560 DNA polymerase IIIC inhibitorACX-362E is an orally available DNA polymerase IIIC (pol IIIC) inhibitor, acts as an antimicrobial agent to treat Gram-positive infections, with a MIC50 of 2 μg/mL for C. difficile. ACX-362E displays very potent in vitro and in vivo activities against broad spectrum of C. difficile pathogens. Learn More -
Triptolide (PG490)
Catalog No. A11596 Triptolide is a diterpene triepoxide, immunosuppresive agent extracted from the Chinese herb Tripterygium wilfordii. Learn More -
Thiolutin
Catalog No. A15386 RNA polymerase InhibitorThiolutin is an RNA polymerase inhibitor, and a sulfur-based microbial antibiotic generated by Streptomyces sp. Learn More -
Mithramycin A
Catalog No. A15385 DNA/RNA polymerase InhibitorMithramycin A is an antibiotic DNA/RNA polymerase and DNA binding transcriptional inhibitor observed to facilitate TNF-α and Fas-ligand induced apoptosis. Learn More -
Oncrasin 1
Catalog No. A15333 RNA polymerase II inhibitorOncrasin 1 is a proapoptotic substance. Induces abnormal nuclear aggregation of PKCι and suppressing RNA transcription. Learn More -
Tenofovir (Viread)
Catalog No. A10908 HIV reverse transcriptase inhibitorTenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Learn More -
BMH-21
Catalog No. A14335 RNA polymerase inhibitorBMH-21 is a potent small molecule DNA intercalator. BMH-21 binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription. Learn More -
Delavirdine mesylate
Catalog No. A13274 NNRT inhibitorDelavirdine is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Learn More -
Fludarabine Phosphate (Fludara)
Catalog No. A10395 Fludarabine or fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies (cancers of blood cells such as leukemias and lymphomas) .Fludarabine inhibits DNA synthesis by interfering with ribonucleotide reductase and DNA polymerase. It is active against both dividing and resting cells. Learn More -
Abacavir
Catalog No. A11115 Transcriptase inhibitorAbacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More -
Abacavir sulfate
Catalog No. A11120 Transcriptase inhibitorAbacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More
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