ROR

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  1. SR1078

    Catalog No. A15245
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    ROR agonist
    SR1078 is an agonist of retinoic acid receptor-related orphan receptors (ROR) RORα/γ; increases transcription of RORα target genes; thought to increase p53 stability. Learn More
  2. SR3335

    Catalog No. A15246
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    RORα agonist
    SR3335 is a selective RORα synthetic ligand, directly binds to RORα, but not other RORs, and functions as a selective partial inverse agonist of RORα in cell-based assays. Learn More
  3. SR1001

    Catalog No. A13193
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    ROR agonist
    SR1001 is a selective ROR-alpha and ROR-gamma inverse agonist; suppresses TH17 cell differentiation and inhibits autoimmunity. Learn More
  4. ROR gamma modulator 1

    Catalog No. A16291
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    RORγ modulator
    RORγ modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extracted from patent WO/2015061515 A1, example 124. Learn More
  5. SR-2211

    Catalog No. A13568
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    RORr agonist
    SR-2211 selectively binds RORr(Ki = 105 nM), acting as an inverse agonist of constitutive in vitro RORr activity (IC50 = 320 nM). Learn More
  6. AGN-242428

    Catalog No. A16935
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    RORγt inhibitor
    AGN-242428, also known as VTP-43742, is a potent, selective and orally active RORγt inhibitor for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis. Learn More
  7. Cintirorgon (LYC-55716)

    Catalog No. A16863
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    RORγ agonist
    LYC-55716 is novel oral RAR-related orphan receptor γ (RORγ) agonist. Learn More

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