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SR1078
Catalog No. A15245 ROR agonistSR1078 is an agonist of retinoic acid receptor-related orphan receptors (ROR) RORα/γ; increases transcription of RORα target genes; thought to increase p53 stability. Learn More -
SR3335
Catalog No. A15246 RORα agonistSR3335 is a selective RORα synthetic ligand, directly binds to RORα, but not other RORs, and functions as a selective partial inverse agonist of RORα in cell-based assays. Learn More -
SR1001
Catalog No. A13193 ROR agonistSR1001 is a selective ROR-alpha and ROR-gamma inverse agonist; suppresses TH17 cell differentiation and inhibits autoimmunity. Learn More -
ROR gamma modulator 1
Catalog No. A16291 RORγ modulatorRORγ modulator 1 is a retinoid-related orphan receptor gamma (RORy) modulator, extracted from patent WO/2015061515 A1, example 124. Learn More -
SR-2211
Catalog No. A13568 RORr agonistSR-2211 selectively binds RORr(Ki = 105 nM), acting as an inverse agonist of constitutive in vitro RORr activity (IC50 = 320 nM). Learn More -
AGN-242428
Catalog No. A16935 RORγt inhibitorAGN-242428, also known as VTP-43742, is a potent, selective and orally active RORγt inhibitor for the treatment of autoimmune disorders, including multiple sclerosis and psoriasis. Learn More -
Cintirorgon (LYC-55716)
Catalog No. A16863 RORγ agonistLYC-55716 is novel oral RAR-related orphan receptor γ (RORγ) agonist. Learn More -
AZD-0284
Catalog No. A18766 RORγ agonistAZD-0284 is a potent, selective, inverse agonist of the nuclear receptor RORγ for the potential treatment of Plaque psoriasis. Learn More -
XY101
Catalog No. A18437 RORγ inverse agonistXY101 is a potent, selective, metabolically stable and orally available RORγ inverse agonist with an IC50 of 30 nM and a Kd of 380 nM. Learn More -
S18-000003
Catalog No. A19105 RORγt inhibitorS18-000003 is a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t (RORγt) inhibitor with an IC50 of 29 nM. S18-000003 inhibits IL-17 production. Learn More -
A-9758
Catalog No. A19078 RORγt inverse agonistA-9758 is a RORγ ligand and a potent, selective RORγt inverse agonist (IC50=5 nM), and exhibits robust potency against IL-17A release. Learn More -
ROR agonist-1
Catalog No. A18569 ROR agonistROR agonist-1 is a potent and orally bioavailable inverse agonist of the retinoic acid receptor-related orphan receptor C2 (RORC2), inhibition of IL-17A production from human primary TH 17 cells with a pIC50 of 7.5. Learn More
12 Item(s)
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