Lipoxygenase

9 Item(s)

per page

Set Descending Direction
  1. Tepoxalin

    Catalog No. A12879
    Quick View
    COX/5-LOX inhibitor
    Tepoxalin is a dual cyclooxygenase/5-lipoxygenase inhibitor of arachidonic acid metabolism with potent anti-inflammatory activity and a favorable gastrointestinal profile Learn More
  2. GSK2190915

    Catalog No. A15818
    Quick View
    FLAP inhibitor
    GSK2190915 is a potent FLAP(5-Lipoxygenase-activating protein) inhibitor with binding IC50 of 2.9 nM. Learn More
  3. AM679

    Catalog No. A14994
    Quick View
    FLAP inhibitor
    AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. Learn More
  4. Nordihydroguaiaretic acid

    Catalog No. A15190
    Quick View
    lipoxygenase inhibitor
    Nordihydroguaiaretic acid is a natural phenolic compound isolated from the creosote bush Larrea divaricata, which has anti-tumor activities both in vitro and in vivo. Its analogs are in clinical development for use in refractory solid tumors. Learn More
  5. MK591

    Catalog No. A15169
    Quick View
    FLAP inhibitor
    MK591 is selective and specific inhibitor of 5-Lipoxygenase-activating protein (FLAP). Learn More
  6. MK-0591 (Quiflapon)

    Catalog No. A15163
    Quick View
    FLAP inhibitor
    MK-0591 is a selective and specific 5-Lipoxygenase-activating protein (FLAP) inhibitor with an IC50 value of 1.6 nM in a FLAP binding assay. Learn More
  7. 6,7-Dihydroxycoumarin

    Catalog No. A14553
    Quick View
    5-lipoxygenase inhibitor
    Esculetin, a phenolic compound, acts as a 5-LO (5-lipoxygenase, 5-LOX) inhibitor. Learn More
  8. MK 886

    Catalog No. A13346
    Quick View
    leukotriene biosynthesis inhibitor
    MK-886 is an inhibitor of leukotriene biosynthesis (IC50 = 3 nM in human polymorphonuclear leukocytes). Learn More
  9. Timegadine

    Catalog No. A17108
    Quick View
    COX and lipo-oxygenase inhibitor
    Timegadine, a new antiinflammatory agent, is found to be a potent, competitive inhibitor of cyclo-oxygenase (COX) and lipo-oxygenase, with IC50s ranging from 5 nM (washed rabbit platelets) to 20 μM (rat brain) for COX and 100 μM for lipo-oxygenase both in the cytosol fraction of horse platelet homogenates, and in washed rabbit platelets. Learn More

9 Item(s)

per page

Set Descending Direction
Rewards