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$0.00 Toll-like Receptors
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Resiquimod
Catalog No. A15890 TLR7/8 AgonistResiquimod is an immune response modifier that acts as a potent TLR 7/8 agonist. Phase 2. Learn More -
AN-3485
Catalog No. A20989 TLR inhibitorAN-3485 is a benzoxaborole analog, Toll-Like Receptor(TLR) inhibitor with IC50 values ranging from 18 to 580 nM. Learn More -
TLR7/8 agonist 1 dihydrochloride
Catalog No. A21700 TLR7/8 agonistTLR7/8 agonist 1 dihydrochloride is a toll-like receptor (TLR7)/TLR8 dual-agonistic imidazoquinoline. Learn More -
Resatorvid
Catalog No. A11543 TLR4 inhibitorResatorvid (TAK-242) is a selective Toll-like receptor 4 (TLR4) inhibitor and plays pivotal role in various inflammatory diseases. Learn More -
PF-4878691
Catalog No. A12233 TLR7 agonistPF-4878691 (3M-852A) is a potent, orally active, and selective Toll-like receptor 7 (TLR7) agonist modelled to dissociate its antiviral and inflammatory activities. Learn More -
MD2-TLR4-IN-1
Catalog No. A18452 MD2-TLR4 inhibitorMD2-TLR4-IN-1 (compound 22m) is an inhibitor of myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex, inhibiting lipopolysaccharides (LPS)-induced expression of tumor necrosis factor alpha (TNF-α) and interleukin-6 (IL-6) in macrophages with IC50 values of 0.89 μM and 0.53 μM, respectively. Learn More -
IAXO-102
Catalog No. A18543 TLR4 antagonistIAXO-102 is a TLR4 antagonist which negatively regulates TLR4 signalling. It inhibits MAPK and p65 NF-κB phosphorylation and expression of TLR4 dependent proinflammatory protein. Learn More -
Imiquimod (Aldara)
Catalog No. A10469 TLR7 agonistImiquimod (Aldara) is a a heterocyclic imidazoquinoline amide that acts as an immune response modifier. Learn More -
Isatoribine
Catalog No. A14351 TLR7 agonistIsatoribine is a novel guanosine analogue showing immunostimulatory activity both in vivo and in vitro. Learn More -
TAK-242 S enantiomer
Catalog No. A15253 TLR4 InhibitorS enantiomer of TAK-242. TAK-242 (Resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock. Learn More -
GS-9620
Catalog No. A13251 TLR7 agonistGS-9620 is a potent and selective orally active small molecule agonist of Toll-like receptor 7. Learn More -
Toll-like receptor modulator
Catalog No. A15264 Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. Learn More -
Gardiquimod TFA
Catalog No. A17050 TLR7 agonistGardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. CAS: 1159840-61-5 (TFA) 1020412-43-4 (free base) Learn More -
TLR2-IN-C29
Catalog No. A17160 TLR InhibitorTLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. Learn More -
TLR7-agonist-1
Catalog No. A17018 TLR7 agonistTLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM. Learn More -
Hydroxychloroquine Sulfate
Catalog No. A14208 Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Learn More -
VGX-1027
Catalog No. A12548 TLR4 InhibitorVGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling. Learn More -
VTX-2337
Catalog No. A12841 TLR8 agonistVTX-2337 is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activities. Learn More -
Toll-Like Receptor 7 Ligand II
Catalog No. A12683 TLR7 LigandToll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro . Learn More
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