Toll-like Receptors

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  1. Imiquimod (Aldara)

    Catalog No. A10469
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    TLR7 agonist
    Imiquimod (Aldara) is a a heterocyclic imidazoquinoline amide that acts as an immune response modifier. Learn More
  2. Resiquimod

    Catalog No. A15890
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    TLR7/8 Agonist
    Resiquimod is an immune response modifier that acts as a potent TLR 7/8 agonist. Phase 2. Learn More
  3. Isatoribine

    Catalog No. A14351
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    TLR7 agonist
    Isatoribine is a novel guanosine analogue showing immunostimulatory activity both in vivo and in vitro. Learn More
  4. TAK-242 S enantiomer

    Catalog No. A15253
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    TLR4 Inhibitor
    S enantiomer of TAK-242. TAK-242 (Resatorvid), a small-molecule inhibitor of Toll-like receptor (TLR) 4 signaling. TAK-242 is in treatment of sepsis and septic shock. Learn More
  5. GS-9620

    Catalog No. A13251
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    TLR7 agonist
    GS-9620 is a potent and selective orally active small molecule agonist of Toll-like receptor 7. Learn More
  6. VGX-1027

    Catalog No. A12548
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    TLR4 Inhibitor
    VGX-1027 displays immunomodulatory and anti-inflammatory activities by inhibiting toll-like receptor 4 (TLR4) signaling. Learn More
  7. Hydroxychloroquine Sulfate

    Catalog No. A14208
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    Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Learn More
  8. Toll-like receptor modulator

    Catalog No. A15264
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    Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. Learn More
  9. VTX-2337

    Catalog No. A12841
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    TLR8 agonist
    VTX-2337 is a small-molecule Toll-like receptor 8 (TLR8) agonist with potential immunostimulating and antineoplastic activities. Learn More
  10. Toll-Like Receptor 7 Ligand II

    Catalog No. A12683
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    TLR7 Ligand
    Toll-Like Receptor 7 Ligand II is a cell-permeable hydroxyadenine compound which acts as a potent and highly specific TLR7 (toll-like receptor 7) agonist without any detectable activity towards TLR2/3/5/8/9. It is shown to be 10-times more potent than R848 in stimulating the production of TLR7-dependent cytokines in cultures in vitro . Learn More
  11. Gardiquimod TFA

    Catalog No. A17050
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    TLR7 agonist
    Gardiquimod is a chemical compound which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. CAS: 1159840-61-5 (TFA) 1020412-43-4 (free base) Learn More
  12. TLR2-IN-C29

    Catalog No. A17160
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    TLR Inhibitor
    TLR2-IN-C29 is an inhibitor of TLR2/1 and TLR2/6 signaling. Learn More
  13. TLR7-agonist-1

    Catalog No. A17018
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    TLR7 agonist
    TLR7-agonist-1 is a potent and selective Toll-like Receptor 7 (TLR7) agonist with a LEC of 0.4 μM. Learn More

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