Kinesin

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Catalog No.
Product Name
Application
Product Information
Product Citation
  1. KSP Inhibitor

    Ispinesib (SB-715992) is a potent inhibitor of kinesin spindle protein, a kinesin motor protein essential for the formation of a bipolar mitotic spindle and cell cycle progression through mitosis.
  2. KSP Inhibitor

    SB 743921, a second generation KSP inhibitor, is a highly potent and active therapeutic in preclinical models of cancer.
  3. KSP inhibitor

    KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5) with potential antineoplastic activity.
  4. Mps1 inhibitor

    AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.

  5. CENP-E inhibitor

    GSK-923295, is a small-molecule inhibitor of the mitotic kinesin centromere-associated protein E, (CENP-E).
  6. Kinesin-5(KIF11) inhibitor

    Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrol blocks mitosis (IC5N/A = 14 μM) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.
  7. TTK inhibitor

    CFI-402257, a pyrazolopyridin derivative, has been found to be a TTK inhibitor that could influence chromosome segregation and induce cell death so that is significant in anticancer studies.
  8. Microtubule Associated inhibitor

    CW069 is an allosteric, and selective inhibitor of microtubule motor protein HSET with IC50 of 75 uM, significant selectivity over KSP.
  9. Eg5 mitotic motor protein inhibitor

    ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor.
  10. Mps1 inhibitor

    MPI-0479605 is an ATP competitive and selective inhibitor of mitotic kinase Mps1
  11. KSP inhibitor

    ARRY-520 R enantiomer is the R form of ARRY-520, which is a synthetic, small molecule kinesin spindle protein (KSP) inhibitor with IC50 of 6 nM.
  12. Kinesin Eg5 inhibitor

    Dimethylenastron is an inhibitor of mitotic motor kinesin Eg5 with IC50 value of 200 nM.
  13. Kinesin Eg5 inhibitor

    K 858 is a selective ATP-uncompetitive mitotic kinesin Eg5 inhibitor with IC50 value of 1.3 uM.
  14. Kinesin inhibitor

    EMD534085 is a kinesin inhibitor currently in clinical development.
  15. TTK (Mps1) and CLK2 dual inhibitor

    CC-671 is a potent and selective dual inhibitor of TTK (Mps1) and CLK2.
  16. kinesin Eg5 inhibitor

    Eg5 Inhibitor V, trans-24 is a potent and specific kinesin Eg5 inhibitor with an IC50 of 0.65 μM, and can be used in the research of cancer.
  17. MPS1 checkpoint inhibitor

    BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 2 nM.
  18. Kif15 inhibitor

    Kif15-IN-2 is an inhibitor of the mitotic kinesin Kif15, and is used for the research of cellular proliferative diseases.
  19. Kif15 inhibitor

    Kif15-IN-1 is an inhibitor of the mitotic Kinesin family member 15 (Kif15), and is used for the research of cellular proliferative diseases.
  20. HSET/KIFC1 inhibitor

    AZ82 is a selective kinesin-like protein KIFC1 (HSET/KIFC1) inhibitor, with a Ki of 43 nM and an IC50 of 300 nM for KIFC1.
  21. kinesin Eg5 inhibitor

    Litronesib (Racemate) is the racemate of litronesib. Litronesib is a selective, allosteric inhibitor of kinesin Eg5.
  22. MPS1 kinase inhibitor

    BAY 1217389 is a potent, and selective inhibitor of the monopolar spindle 1 (MPS1) kinase with an IC50 value less than 10 nM.
  23. MPS1 kinase inhibitor

    Mps1-IN-3 is a potent and selective MPS1 kinase inhibitor, with an IC50 of 50 nM.
  24. Mps1 inhibitor

    Empesertib (BAY 1161909) is a potent Mps1 inhibitor, with an IC50 of < 1 nM.
  25. MPS1 inhibitor

    NMS-P715 is a selective, ATP-competitive inhibitor of MPS1, with an IC50 of 182 nM.
  26. MPS1 inhibitor

    CCT251455 is a potent and selective mitotic kinase monopolar spindle 1 (MPS1) inhibitor with an IC50 of 3 nM.
  27. mitosis-specific kinesin Eg5 inhibitor

    Litronesib is a selective mitosis-specific kinesin Eg5 inhibitor, with antitumor activity.
  28. dual Mps1/Plk1 inhibitor

    Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor, with an IC50 and a Kd of 145 nM and 12 nM for Mps1 and a Kd of 61 nM for Plk1.

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