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| Catalog No. | Inhibitor Name | Reverse Transcriptase | Other |
|---|---|---|---|
| A10306 | Didanosine | ** | |
| A12587 | Dapivirine (TMC120) | *** | |
| A10908 | Tenofovir | ||
| A10909 | Tenofovir Disoproxil Fumarate | ||
| A10349 | Emtricitabine | ||
| A11216 | Entecavir Hydrate | ||
| A10039 | Adefovir Dipivoxil | ||
| A10639 | Nevirapine | ||
| A10512 | Lamivudine | ||
| A15428 | Zidovudine | ||
| A11120 | Abacavir sulfate | ||
| A11542 | Rilpivirine |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
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Loviride
Catalog No. A21996 non-nucleoside reverse transcriptase inhibitorLoviride (R 89439) is a non-nucleoside reverse transcriptase inhibitor (NNRTI), with an IC50 of 0.3 ?M for reverse transcriptase from HIV-1. Loviride (R 89439) inhibits HIV-1, HIV-2 and SIV replication in MT-4 cells. Learn More -
4'-Ethynyl-2'-deoxyadenosine
Catalog No. A18513 nucleoside reverse transcriptase (RT) inhibitor4'-Ethynyl-2'-deoxyadenosine (4'-E-dA), a nucleoside reverse transcriptase (RT) inhibitor, is an antiretroviral agent which is potent against drug-resistant HIV variants, with an EC50 of 98 nM in MT-4 cells for anti-HIV-1 activity. Learn More -
Etravirine ( R165335, TMC125)
Catalog No. A11417 NNRT inhibitorEtravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV. Learn More -
MIV-150
Catalog No. A12060 NNRT inhibitorMIV-150 is a nonnucleoside reverse transcriptase (NNRT) inhibitor, blocking HIV-1 and HIV-2 infections, with an EC50<1 nM against HIV-1/HIV-2MN. Learn More -
Zalcitabine
Catalog No. A11005 nucleoside analogue reverse transcriptase inhibitorZalcitabine is a potent nucleoside analogue reverse transcriptase inhibitor used in the treatment of HIV infection. Learn More -
Tenofovir Disoproxil
Catalog No. A18041 nucleotide reverse transcriptase inhibitorTenofovir Disoproxil (Bis(POC)-PMPA) is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Learn More -
Tenofovir hydrate
Catalog No. A18042 nucleotide reverse transcriptase inhibitorTenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Learn More -
Tenofovir alafenamide fumarate
Catalog No. A18049 HIV-1 nucleotide reverse transcriptase inhibitorTenofovir alafenamide fumarate (GS-7340 fumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. Learn More -
Tenofovir alafenamide hemifumarate
Catalog No. A18050 HIV-1 nucleotide reverse transcriptase inhibitorTenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an investigational oral prodrug of Tenofovir. Tenofovir is a HIV-1 nucleotide reverse transcriptase inhibitor. Learn More -
Delavirdine
Catalog No. A21469 non-nucleoside reverse transcriptase inhibitorDelavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI). Learn More -
Tenofovir maleate
Catalog No. A21776 nucleotide reverse transcriptase inhibitorTenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Learn More -
Delavirdine mesylate
Catalog No. A13274 NNRT inhibitorDelavirdine is a potent inhibitor of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Learn More -
(Z)-9-Propenyladenine
Catalog No. A21687 (Z)-9-Propenyladenine is a mutagenic impurity in tenofovir disoproxil fumarate. Tenofovir is an antiretroviral drug known as nucleotide analogue reverse transcriptase (NtART) inhibitor, which blocks reverse transcriptase, a crucial virus enzyme in HIV-1 and HBV. Learn More -
GS-7340
Catalog No. A15772 NRT inhibitorGS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate. Learn More -
Zidovudine
Catalog No. A15428 NRTI InhibitorZidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency. Learn More -
Elvucitabine
Catalog No. A14435 NRT inhibitorElvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI). Learn More -
Lamivudine
Catalog No. A10512 Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). Learn More -
Entecavir hydrate
Catalog No. A11216 Reverse transcriptase inhibitorEntecavir hydrate is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. Learn More -
Tenofovir Disoproxil Fumarate
Catalog No. A10909 nucleotide reverse transcriptase inhibitorTenofovir Disoproxil Fumarate is employed as an anti-HIV agend and a reverse transcriptase inhibitor. Learn More -
Abacavir sulfate
Catalog No. A11120 Transcriptase inhibitorAbacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More -
Abacavir
Catalog No. A11115 Transcriptase inhibitorAbacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More -
Adefovir dipivoxil
Catalog No. A10039 ntRT inhibitorAdefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection. Learn More -
Rilpivirine (R 278474, TMC 278)
Catalog No. A11542 NNRT inhibitorRilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. Learn More -
Emtricitabine
Catalog No. A10349 NRT inhibitorEmtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection. Learn More -
Didanosine
Catalog No. A10306 Reverse transcriptase inhibitorDidanosine is a reverse transcriptase inhibitor, effective against HIV and used in combination with other antiretroviral drug therapy as part of highly active antiretroviral therapy (HAART). Learn More -
MK-1439
Catalog No. A12443 -
Nevirapine (Viramune)
Catalog No. A10639 Nevirapine (Viramune) is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Learn More -
Dapivirine
Catalog No. A12587 HIV reverse transcriptase inhibitorDapivirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) Learn More -
Lersivirine (UK-453061)
Catalog No. A12667 NNRT inhibitorLersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type HIV-1 and several nonnucleoside reverse transcriptase inhibitor-resistant strains. Learn More -
Tenofovir (Viread)
Catalog No. A10908 HIV reverse transcriptase inhibitorTenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Learn More
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