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Reverse Transcriptase
Inhibitory Selectivity
| Catalog No. | Inhibitor Name | Reverse Transcriptase | Other |
|---|---|---|---|
| A10306 | Didanosine | ** | |
| A12587 | Dapivirine (TMC120) | *** | |
| A10908 | Tenofovir | ||
| A10909 | Tenofovir Disoproxil Fumarate | ||
| A10349 | Emtricitabine | ||
| A11216 | Entecavir Hydrate | ||
| A10039 | Adefovir Dipivoxil | ||
| A10639 | Nevirapine | ||
| A10512 | Lamivudine | ||
| A15428 | Zidovudine | ||
| A11120 | Abacavir sulfate | ||
| A11542 | Rilpivirine |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
17 Item(s)
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| Catalog No. | Product Name | Application | Product Information |
|---|---|---|---|
A10908 SALE |
Tenofovir (Viread) |
HIV reverse transcriptase inhibitor |
Tenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood.
|
A15428 |
Zidovudine
|
NRTI Inhibitor |
Zidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency.
|
A14435 |
Elvucitabine |
NRT inhibitor |
Elvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI).
|
A10512 SALE |
Lamivudine |
- |
Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI).
|
A12667 |
Lersivirine (UK-453061) |
NNRT inhibitor |
Lersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type HIV-1 and several nonnucleoside reverse transcriptase inhibitor-resistant strains.
|
A12587 SALE |
Dapivirine |
HIV reverse transcriptase inhibitor |
Dapivirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI)
|
A10639 SALE |
Nevirapine (Viramune) |
- |
Nevirapine (Viramune) is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase.
|
A12443 |
MK-1439 |
NNRT inhibitor |
MK-1439 is a non-nucleoside reverse transcriptase inhibitor
|
A10306 |
Didanosine |
Reverse transcriptase inhibitor |
Didanosine is a reverse transcriptase inhibitor, effective against HIV and used in combination with other antiretroviral drug therapy as part of highly active antiretroviral therapy (HAART).
|
A10349 SALE |
Emtricitabine |
NRT inhibitor |
Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection.
|
A11542 SALE |
Rilpivirine (R 278474, TMC 278) |
NNRT inhibitor |
Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz.
|
A10039 SALE |
Adefovir dipivoxil |
- |
Adefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection.
|
A11115 SALE |
Abacavir |
Transcriptase inhibitor |
Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
|
A11120 SALE |
Abacavir sulfate |
Transcriptase inhibitor |
Abacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS.
|
A10909 SALE |
Tenofovir Disoproxil Fumarate |
nucleotide reverse transcriptase inhibitor |
Tenofovir Disoproxil Fumarate is employed as an anti-HIV agend and a reverse transcriptase inhibitor.
|
A11216 SALE |
Entecavir |
Reverse transcriptase inhibitor |
Entecavir is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection.
|
A15772 |
GS-7340
|
NRT inhibitor |
GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate.
|
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