Reverse Transcriptase

Catalog No.Inhibitor Name Reverse TranscriptaseOther
A10306Didanosine
**
A12587Dapivirine (TMC120)
***
A10908Tenofovir
A10909Tenofovir Disoproxil Fumarate
A10349Emtricitabine
A11216Entecavir Hydrate
A10039Adefovir Dipivoxil
A10639Nevirapine
A10512Lamivudine
A15428Zidovudine
A11120Abacavir sulfate
A11542Rilpivirine

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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  1. Tenofovir (Viread)

    Catalog No. A10908
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    HIV reverse transcriptase inhibitor
    Tenofovir is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV in the blood. Learn More
  2. Zidovudine

    Catalog No. A15428
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    NRTI Inhibitor
    Zidovudine is a nucleoside analog reverse-transcriptase inhibitor (NRTI), a type of antiretroviral drug used for the treatment of HIV/AIDS infection. Azidothymidine decreases CRISPR-mediated homology directed repair (HDR) efficiency. Learn More
  3. Elvucitabine

    Catalog No. A14435
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    NRT inhibitor
    Elvucitabine is an experimental nucleoside reverse transcriptase inhibitor (NRTI). Learn More
  4. Lamivudine

    Catalog No. A10512
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    Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). Learn More
  5. Lersivirine (UK-453061)

    Catalog No. A12667
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    NNRT inhibitor
    Lersivirine (UK-453,061) is a next-generation nonnucleoside reverse transcriptase inhibitor, active against wild-type HIV-1 and several nonnucleoside reverse transcriptase inhibitor-resistant strains. Learn More
  6. Dapivirine

    Catalog No. A12587
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    HIV reverse transcriptase inhibitor
    Dapivirine is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI) Learn More
  7. Nevirapine (Viramune)

    Catalog No. A10639
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    Nevirapine (Viramune) is a potent (IC50=84nM) and selective non-nucleoside inhibitor of HIV-1 reverse transcriptase. Learn More
  8. MK-1439

    Catalog No. A12443
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    NNRT inhibitor
    MK-1439 is a non-nucleoside reverse transcriptase inhibitor Learn More
  9. Didanosine

    Catalog No. A10306
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    Reverse transcriptase inhibitor
    Didanosine is a reverse transcriptase inhibitor, effective against HIV and used in combination with other antiretroviral drug therapy as part of highly active antiretroviral therapy (HAART). Learn More
  10. Emtricitabine

    Catalog No. A10349
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    NRT inhibitor
    Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) for the treatment of HIV infection. Learn More
  11. Rilpivirine (R 278474, TMC 278)

    Catalog No. A11542
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    NNRT inhibitor
    Rilpivirine is a second-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) with higher potency, longer half-life and reduced side-effect profile compared with older NNRTIs, such as efavirenz. Learn More
  12. Adefovir dipivoxil

    Catalog No. A10039
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    Adefovir dipivoxil is an orally-administered nucleotide analog reverse transcriptase inhibitor (ntRTI). It is used for treatment of hepatitis B and herpes simplex virus infection. Learn More
  13. Abacavir

    Catalog No. A11115
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    Transcriptase inhibitor
    Abacavir is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More
  14. Abacavir sulfate

    Catalog No. A11120
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    Transcriptase inhibitor
    Abacavir sulfate is a nucleoside analog reverse transcriptase inhibitor (NRTI); guanosine analog used to treat HIV and AIDS. Learn More
  15. Tenofovir Disoproxil Fumarate

    Catalog No. A10909
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    nucleotide reverse transcriptase inhibitor
    Tenofovir Disoproxil Fumarate is employed as an anti-HIV agend and a reverse transcriptase inhibitor. Learn More
  16. Entecavir

    Catalog No. A11216
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    Reverse transcriptase inhibitor
    Entecavir is a nucleoside analog (more specifically, a guanosine analogue) that inhibits reverse transcription, DNA replication and transcription in the viral replication process. Entecavir is an oral antiviral drug used in the treatment of hepatitis B infection. Learn More
  17. GS-7340

    Catalog No. A15772
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    NRT inhibitor
    GS-7340 is a prodrug of tenofovir (TFV) that more efficiently delivers TFV into lymphoid cells and tissues than TFV disoproxil fumarate. Learn More

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