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$0.00 Isocitrate Dehydrogenase (IDH)
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Mutant IDH1 inhibitor
Catalog No. A21150 mutant IDH1 R132H inhibitorMutant IDH1 inhibitor is a potent mutant IDH1 R132H inhibitor with IC50 of < 72 nM. Learn More -
Mutant IDH1-IN-2
Catalog No. A21339 IDH inhibitorMutant IDH1-IN-2 is a inhibitor of mutant Isocitrate dehydrogenase (IDH) proteins, with IC50 of in LS-MS biochemical assay, IC50 of 16.6 nM in Fluorescence biochemical assay. Learn More -
Mutant IDH1-IN-1
Catalog No. A21359 mutant-selective IDH1 inhibitorMutant IDH1-IN-1 is a mutant-selective IDH1 inhibitor with with IC50s of 4, 42, 80 and 143 nM against mutant IDH1 R132C/R132C, IDH1 R132H/R132H, IDH1 R132H/WT and wild type IDH1, respectively. Learn More -
AGI-5198 (IDH-C35)
Catalog No. A12902 IDH1 inhibitorAGI-5198, also know as IDH-C35, is the a very potent and selective mutant IDH1 inhibitor that was shown to potential anticancer activity. Learn More -
AGI-6780
Catalog No. A12903 IDH2 R140Q inhibitorAGI-6780 is a potent, selective inhibitor of mutant IDH2 with an IC50 value of 23 nM. Learn More -
IDH-C227
Catalog No. A12923 IDH1 R132H inhibitorIDH-C227 is a potent and selective IDH1 R132H inhibitor. Learn More -
Enasidenib
Catalog No. A15808 IDH2 inhibitorEnasidenib is a potent and selective IDH2 inhibitor with potential anticancer activity (IDH2 = Isocitrate dehydrogenase 2). Learn More -
AG-120 (Ivosidenib)
Catalog No. A14386 IDH1 inhibitorAG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Learn More -
IDH-305
Catalog No. A16943 IDH1 inhibitorIDH305 is an inhibitor of the citric acid cycle enzyme isocitrate dehydrogenase [NADP] cytoplasmic (isocitrate dehydrogenase 1; IDH1) with mutations at residue R132 (IDH1(R132)), with potential antineoplastic activity. Learn More -
Vorasidenib
Catalog No. A16908 IDH1 InhibitorVorasidenib, also known as AG-881, is a potent and selective orally available inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP+], mitochondrial) in the mitochondria, with potential antineoplastic activity. Learn More -
BAY-1436032
Catalog No. A17059 mIDH1 inhibitorBAY-1436032 is a potent, selective and orally available inhibitor of mutant Isocitrate Dehydrogenase 1 (mIDH1). Learn More -
Olutasidenib (FT-2102)
Catalog No. A18789 IDH1 inhibitorOlutasidenib is a potent, selective inhibitor of mutant Isocitrate dehydrogenase (IDH)1 for the treatment of acute myeloid leukemia. Learn More -
Mutant IDH1-IN-4
Catalog No. A19106 IDH1 inhibitorMutant IDH1-IN-4 (compound 434) is an inhibitor of mutant Isocitrate dehydrogenase 1 (IDH 1), with IC50 values of ?? 0.5 μM for mutant IDH1 in R132H, HT1080 and U87R132H cells. Learn More -
IDH1 Inhibitor 2
Catalog No. A18420 IDH1 inhibitorDH1 Inhibitor 2 is a potent IDH1 inhibitor via a direct covalent modification of His315, with an IC50 of 110 nM. Learn More
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