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Beta-secretase (BACE)

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Catalog No. Product Name Application Product Information


BACE1 inhibitor
LY2886721 is a novel potent agent that is used to treat Alzheimer's Disease in preclinical experiments.
A11776 SALE


BACE1 inhibitor
LY2811376 is the first orally available non-peptidic BACE1 inhibitor that produces profound Aβ-lowering effects in animals.


BACE1 inhibitor
AZD3839 is a potent and selective inhibitor of human BACE1 with Ki of 26.1 nM.


nonsteroidal glucocorticoid receptor agonist
AZD5423 is a novel nonsteroidal glucocorticoid receptor agonist.


BACE1 inhibitor
AMG-8718 is a potent and orally efficacious BACE1 inhibitor.

Timosaponin b-II

BACE1 Inhibitor
Timosaponin B-II is a major active component of Anemarrhena asphodeloides Bunge (Liliaceae, rhizome) that has protective effects against cerebral ischaemic damage.

Verubecestat (MK-8931)

β-secretase/BACE1 inhibitor
Verubecesta is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor.

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