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$0.00 Beta-secretase (BACE)
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Lanabecestat
Catalog No. A12282 BACE1 inhibitorLanabecestat (AZD3293) is a potent, highly permeable, orally active and blood-brain barrier penetrating BACE1 inhibitor with a Ki of 0.4 nM. Learn More -
BACE1-IN-1
Catalog No. A12183 BACE1 inhibitorBACE1-IN-1 is a potent and highly brain penetrant BACE1 inhibitor with IC50s of 32 and 47 nM for human BACE1 and BACE2, respectively. Learn More -
β-Secretase Inhibitor IV
Catalog No. A21346 BACE-1 inhibitorβ-Secretase Inhibitor IV is a potent, cell-active BACE-1 inhibitor with IC50s of 15.6 and 16.3nM under BACE-1 concentrations of 2 nM and 100 pM, respectively. Learn More -
AZD3839 free base
Catalog No. A21606 BACE1 inhibitorAZD3839 (free base) is a potent and selective BACE1 inhibitor with IC50 of 23.6 uM, about 14-fold selectivity over BACE2, also a β-secretase enzyme inhibitor. Learn More -
LY2886721
Catalog No. A10543 BACE1 inhibitorLY2886721 is a novel potent agent that is used to treat Alzheimer's Disease in preclinical experiments. Learn More -
LY2811376
Catalog No. A11776 BACE1 inhibitorLY2811376 is the first orally available non-peptidic BACE1 inhibitor that produces profound Aβ-lowering effects in animals. Learn More -
AZD3839
Catalog No. A12825 BACE1 inhibitorAZD3839 is a potent and selective inhibitor of human BACE1 with Ki of 26.1 nM. Learn More -
AZD5423
Catalog No. A13249 nonsteroidal glucocorticoid receptor agonistAZD5423 is a novel nonsteroidal glucocorticoid receptor agonist. Learn More -
AMG-8718
Catalog No. A14407 BACE1 inhibitorAMG-8718 is a potent and orally efficacious BACE1 inhibitor. Learn More -
Timosaponin b-II
Catalog No. A14591 BACE1 InhibitorTimosaponin B-II is a major active component of Anemarrhena asphodeloides Bunge (Liliaceae, rhizome) that has protective effects against cerebral ischaemic damage. Learn More -
Verubecestat (MK-8931)
Catalog No. A16113 β-secretase/BACE1 inhibitorVerubecesta is a potent and selective beta-secretase inhibitor, and BACE1 protein inhibitor or Beta-site APP-cleaving enzyme 1 inhibitor. Learn More -
BACE1-IN-4
Catalog No. A18462 BACE1 inhibitorBACE1-IN-4 is a potent and highly selective BACE1 inhibitor, with an IC50 of 3.8 nM and a Ki of 1.9 nM, more selective at BACE1 over BACE2. Anti-Alzheimer's disease. Learn More -
PF-06751979
Catalog No. A20066 BACE1 inhibitorPF-06751979 is a potent, brain penetrant, β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor with an IC50 of 7.3 nM in BACE1 binding assay. Learn More -
Umibecestat (CNP520)
Catalog No. A18987 BACE-1 inhibitorUmibecestat (CNP520) is a beta-site amyloid precursor protein cleaving enzyme-1 (BACE-1) inhibitor with IC50s of 11 nM and 10 nM for human BACE-1 and mouse BACE-1, respectively. Learn More
14 Item(s)
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