Total item
Cart Subtotal
$0.00 DPP-4
| Catalog No. | Inhibitor Name | DPP-4 |
|---|---|---|
| A10848 | Sitagliptin phosphate monohydrate | ** |
| A11224 | Linagliptin | **** |
| A12528 | Vildagliptin (LAF-237) | *** |
| A11109 | Saxagliptin | * |
| A13571 | Alogliptin | *** |
| A14293 | Trelagliptin |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
29 Item(s)
per page
-
NVP DPP 728 dihydrochloride
Catalog No. A15320 DPP-4 inhibitorNVP DPP 728 dihydrochloride is a potent and orally active inhibitor of dipeptidyl peptidase (DPP)-IV with Ki and IC50 values of 11 nM and 14 nM, respectively. Learn More -
Vildagliptin dihydrate
Catalog No. A21898 DPP4 inhibitorVildagliptin (LAF237 dihydrate;NVP-LAF 237 dihydrate) is a dipeptidyl peptidase 4 (DPP4) inhibitor that delays the degradation of glucagon-like peptide-1 (GLP-1). Learn More -
DBPR108
Catalog No. A21833 DPP4 inhibitorDBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9. Learn More -
Dutogliptin
Catalog No. A21573 DPP4 inhibitorDutogliptin (PHX-1149 free base) is an orally available, potent, and selective dipeptidyl peptidase-4 (DPP4) inhibitor for the treatment of type 2 diabetes mellitus. Learn More -
Gosogliptin
Catalog No. A21566 DPP-IV inhibitorGosogliptin is a potent and selective inhibitor of dipeptidyl peptidase-IV (DPP-IV). Learn More -
Diprotin A TFA
Catalog No. A21475 DPP IV inhibitorDiprotin A (TFA) is an inhibitor of dipeptidyl peptidase IV (DPP-IV). Learn More -
Teneligliptin hydrobromide hydrate
Catalog No. A21465 DPP-4 inhibitorTeneligliptin hydrobromide hydrate is a potent chemotype prolylthiazolidine-based DPP-4 inhibitor, which competitively inhibits human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50s of approximately 1 nM. Learn More -
Gemigliptin
Catalog No. A21285 DPP4 inhibitorGemigliptin is a highly selective dipeptidyl peptidase 4 (DPP4) inhibitor with a KD of 7.25 nM. Learn More -
Saxagliptin hydrate
Catalog No. A16694 DPP4 inhibitorSaxagliptin H2O(BMS477118 H2O) is a selective and reversible DPP4 inhibitor with IC50 of 26 nM and Ki of 1.3 nM. Learn More -
Talabostat
Catalog No. A14079 DPP-IV inhibitorTalabostat (Val-boroPro; PT100) is an orally active and nonselective dipeptidyl peptidase IV (DPP-IV) inhibitor (IC50 < 4 nM; Ki = 0.18 nM) and the first clinical inhibitor of fibroblast activation protein (FAP) (IC50 = 560 nM). Learn More -
1G244
Catalog No. A18709 -
AZD7986
Catalog No. A17095 DPPI inhibitorAZD7986, also known as INS 1007, is a second generation reversible covalent, potent and selective DPP1 inhibitor potentially for the treatment of chronic obstructive pulmonary disease (COPD) with predicted human PK properties suitable for once daily human dosing. Learn More -
Teneligliptin
Catalog No. A15505 DPP-4 inhibitorTeneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM. Learn More -
PK 44 phosphate
Catalog No. A15309 DPP-4 inhibitorPK 44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) with an IC50 value of 15.8 nM. Learn More -
DPPI 1c hydrochloride
Catalog No. A15298 DPP-4 inhibitorDPPI 1c hydrochloride is a dicyanopyrrolidine compound that acts as a slow-binding and active site-targeting inhibitor of CD26 (DPP 4), with an IC50 = 106 nM and little activity against DPP II, DPP III, DPP VIII, DPP IX, FAP, or APP even at concentrations as high as 30 μM. Learn More -
Teneligliptin hydrobromide
Catalog No. A15258 DPP-4 inhibitorTeneligliptin is a novel, potent, and long-lasting dipeptidyl peptidase-4 inhibitor; competitively inhibited human plasma, rat plasma, and human recombinant DPP-4 in vitro, with IC50 values of approximately 1 nM. Learn More -
Saxagliptin (BMS-477118)
Catalog No. A11109 DPP-4 InhibitorSaxagliptin (BMS-477118) is a new dipeptidyl peptidase-4 (DPP-4) inhibitor with IC50 of 50 nM. Learn More -
UAMC 00039 dihydrochloride
Catalog No. A16047 DPP-II inhibitorUAMC 00039 dihydrochloride is a potent inhibitor of dipeptidyl peptidase II (DPP-II) (IC50 = 0.48 nM). Exhibits selectivity for DPP-II against DPP-9, DPP-8 and DPP-IV (IC50 values are 78.6, 142 and 165 μM, respectively). Learn More -
Talabostat mesylate
Catalog No. A14080 DPP-4 inhibitorTalabostat mesylate is a potent, nonselective and orally available dipeptidyl peptidase IV (DPP-IV) inhibitor with a Ki of 0.18 nM. Learn More -
Anagliptin
Catalog No. A13529 DPP-4 inhibitorAnagliptin is a potent and selective DPP-4 inhibitor(IC50= 3.8 nM); > 10 fold less potent for DPP-8 and DPP-9. Learn More -
Alogliptin
Catalog No. A13571 DPP-4 inhibitorAlogliptin is a potent, selective inhibitor of DPP-4 with IC50 of <10 nM, exhibits greater than 10,000-fold selectivity over DPP-8 and DPP-9. Learn More -
Sitagliptin
Catalog No. A14377 DDP-4 inhibitorSitagliptin is an oral antihyperglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class. Learn More -
Trelagliptin
Catalog No. A14293 DPP-4 inhibitorTrelagliptin is a highly selective, long-acting DPP-4 inhibitor. Learn More -
Trelagliptin Succinate (SYR-472)
Catalog No. A13312 DPP-4 inhibitorTrelagliptin is a long acting dipeptidyl peptidase-4 (DPP-4) inhibitor that is being developed for the treatment of type 2 diabetes (T2D). Learn More -
Alogliptin Benzoate
Catalog No. A13311 DPP-4 inhibitorAlogliptin Benzoate is a dipeptidyl-peptidase-4 (DPP 4) inhibitor Learn More -
MK-3102
Catalog No. A13310 DPP-4 inhibitorOmarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5). Learn More -
Vildagliptin
Catalog No. A12528 DPP-IV InhibitorVildagliptin is a dipeptidyl peptidase-4 (CD26) inhibitor. Learn More -
Linagliptin (BI-1356)
Catalog No. A11224 DPP-4 InhibitorLinagliptin is a DPP-4 inhibitor, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Learn More -
Sitagliptin phosphate monohydrate
Catalog No. A10848 DDP-4 inhibitorSitagliptin phosphate is an anti-diabetic (antihyperglycemic) drug of the dipeptidyl peptidase-4 (DPP-4) class. Inhibition of the enzyme DPP-4 is thought to increase Glucagon-like peptide-1 (GLP-1) which inhibits glucagon release , stimulates the insulin release and lowers blood glucose. Learn More
29 Item(s)
per page
FILTER BY:
Shopping Options
- Actions
-
- Inhibitor (29)
Adooq Quality Guarantee
We promise all products perform as described.