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  1. Maraviroc (UK-427857)

    Catalog No. A10556
    CCR antagonist
    Maraviroc is an antiretroviral drug in the CCR5 receptor antagonist class used in the treatment of HIV infection. Learn More
  2. Vicriviroc Malate

    Catalog No. A10971
    CCR5 antagonist
    Vicriviroc Malate is a second generation orally active CCR5 antagonist, which is also a potent inhibitor of HIV-1 entry into target cells, with a mean IC50 =0.46 nM and IC50 =1~10 nM to HIV isolates (n=52). Learn More
  3. INCB8761 (PF-4136309)

    Catalog No. A11136
    CCR2 Antagonist
    INCB8761(PF-4136309) is a potent, selective, and orally bioavailable CCR2 antagonist. Learn More
  4. INCB 3284 dimesylate

    Catalog No. A11104
    HCCR2 antagonist
    INCB 3284 dimesylate is a potent, selective hCCR2 antagonist that exhibits potenct antagonism against monocyte chemoattractant molecule binding to hCCR2 and chemotaxis activity. Learn More
  5. MK-0812

    Catalog No. A11127
    CCR2 antagonist
    MK-0812 is a potent and selective CCR2 antagonist with low nM affinity for CCR2 on human monocytes and low nM in the chemotaxis assay. It has good PK profiles in preclinical species and demonstrated efficacy in animal models. Learn More
  6. RS 504393

    Catalog No. A15227
    CCR2 antagonist.
    RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 98 nM and > 100 uM for inhibition of human recombinant CCR2b and CCR1 receptors respectively). Learn More
  7. Vicriviroc maleate

    Catalog No. A15276
    CCR5 antagonist
    Vicriviroc maleate is a CCR5 antagonist with IC50 of 0.91 nM in clinical development for the treatment of HIV-1. Learn More
  8. NSC5844

    Catalog No. A15924
    CCR1 agonist
    NSC5844 is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic properties. Learn More
  9. ZK-756326 dihydrochloride

    Catalog No. A16363
    CCR8 agonist
    ZK-756326 is a potent, selective and non-peptide CCR8 chemokine receptor agonist. ZK 756326 inhibited the binding of the CCR8 ligand I-309 (CCL1), with an IC(50) value of 1.8 μM. Learn More

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