Catalog No.
Product Name
Application
Product Information
Product Citation
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CDK336 Inhibitor
Pseudolaric Acid A is a diterpene acid isolated from Pseudolarix kaempferi, has antifungal, cytotoxic and antifertile activities. -
anti-fungal agent
Pseudolaric Acid B, a natural diterpenoid compound isolated from the root and trunk bark of Pseudolaric kaempferi Gordon, has anti-fungal and anti-fertility properties. -
Carbonic anhydrase inhibitor
Punicalagin is an ellagitannin, a type of phenolic compounds. It is a highly active carbonic anhydrase inhibitor.- Elizabeth Read, .et al. , ANIM FEED SCI TECH, 2019, May, 251(187-197)
- Quercitrin is known as an bio flavonoid antioxidant and was investigated extensively in its antioxidant potential in streptrozotocin (STZ)-induced diabetic rats.
- Sarsasapogenin is a steroidal sapogenin, that is the aglycosidic portion of a plant saponin. Sarsasapogenin and its C-25 epimer smilagenin lowered blood sugar and reversed diabetic weight gain in experiments within mice with a mutant diabetes gene (db).
- Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects.
- Hasan Aksit, .et al. , Biotech Histochem, 2023, Nov;98(6):432-444 PMID: 37337855
- Stevioside is a reagent that exhibits transepithelial p-aminohippurate transport.
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HMG-CoA reductase inhibitor
Swertiamarin has shown potential as antiatherogenic agent by inhibiting HMG-CoA reductase activity in high cholesterol fed rats. - Tectoridin, an isoflavone glycoside from the flower of Pueraria lobata, prevents acute ethanol-induced liver steatosis in mice.
- Tiliroside, a glycosidic flavonoid, ameliorates obesity-induced metabolic disorders via activation of adiponectin signaling followed by enhancement of fatty acid oxidation in liver and skeletal muscle in obese-diabetic mice.
- Triptonide is a Triptolide analogue used in the preparation of cytotoxic fluorinated Triptolide.
- Vitexicarpin, a flavonoid from the fruits of Vitex rotundifolia, inhibits mouse lymphocyte proliferation and growth of cell lines in vitro.
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plant growth inhibitor
Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. - Chelidonin inhibits tubulin polymerisation (IC50=24 uM), thereby disrupting microtubule structure in cells and inducing a G2/M mitotic arrest.
- Grosvenorine is the major flavonoid compound of the fruits of Siraitia grosvenorii. Grosvenorine exhibits good antibacterial and antioxidant activities.
- Mogroside III-E is a cucurbitane-type compound isolated from Siraitia grosvenorii, inhibits NO release, with anti-fibrotic activity.
- Mogroside III-A1, a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener. Mogrosides are sweeter than sucrose. Mogrosides exhibit antioxidant, antidiabetic and anticancer activities.
- Daurinoline is an alkaloid from the rhizomes of Menispermum canadense and Menispermum dauricum and from Phaeanthus vietnamensis.
- Angelicin is a furanocoumarin typically isolated from the seeds of P. corylifolia. It has also been shown to prevent tacrine-induced cytotoxicity in human liver-derived HepG2 cells (EC50 = 47 ug/ml) and vascular relaxation in phenylephrine-precontracted rat aorta.
- Sandhya R Krishnan, .et al. , Phytochemistry, 2023, Sep;213:113770 PMID: 37331573
- Cyanidin chloride is an anthocyanin polyphenolic antioxidant compound with demonstrated cell protectant effects.
- Daurisoline alkaloid isolated from the rhizomes of Menispermum dauricum that exhibit varies pharmacological activities including antiplatelet aggregation, anti-inflammatory, neuron-protective properties, and antiarrhythmic effect.
- Pterostilbene is a stilbenoid chemically related to resveratrol and is found in blueberries and grapes. Antioxidant, antiproliferative, apoptosis inducer, antihyperglycemic, antidiabetic.
- Astragaloside II induces osteogenic activities of osteoblasts through the bone morphogenetic protein-2/MAPK and Smad1/5/8 pathways.
- Astragaloside I, II, III, and IV concentration-dependently increased the CD45-mediated of pNPP/OMFP hydrolysis with the EC50 values ranged from 3.33 to 10.42 ug/mL.
- Sinomenine hydrochloride enhancement of the inhibitory effects of anti-transferrin receptor antibody-dependent on the COX-2 pathway in human hepatoma cells.
- Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz, has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases.
- Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities.
- Satoshi Endo, .et al. , J Biochem, 2021, Mar 17 PMID: 33729485
- 6-(γ,γ-Dimethylallylamino)purine is a plant growth substance.
- Salvianolic Acid B is isolated and purified from the crude extract of Salvia miltiorrhiza.
- Budesonide is a glucocorticoid steroid for the treatment of asthma and non-infectious rhinitis (including hay fever and other allergies), and for treatment and prevention of nasal polyposis. In addition, it is used for Crohn's disease (inflammatory bowel disease).
- Manool is a labdane diterpenoid in which the labdane skeleton has double bonds at positions 8(17) and 14 and carries an R-hydroxy group at position 13. It has a role as an antineoplastic agent, a plant metabolite and an antibacterial agent. It is a labdane diterpenoid and a tertiary alcohol.
- Procyanidin B3 is a B type proanthocyanidin. Procyanidin B3 is a catechin dimer. It can be found in barley, in beer, in peach or in Jatropha macrantha, the Huanarpo Macho. It has been identified as an hair-growth stimulant
- Darshika Pathiraja, .et al. , Food Chem, 2023, May 1;407:135145 PMID: 36521391
- Keji Yu, .et al. , Nat Commun, 2022, Jun 14;13(1):3425 PMID: 35701431
- Ji Hyung Jun, .et al. , Sci Adv, 2021, May 14;7(20) PMID: 33990337
- Elessawy FM, .et al. , Phytochem Anal, 2019, Dec 23 PMID: 31869515
- Jun JH, .et al. , Nat Plants, 2018, Dec;4(12):1034-1043 PMID: 30478357
- Angela Wang, .et al. , Int J Mol Sci, 2016, Dec; 17(12): 2065 PMID: 27941690
- Chenggang Liu, .et al. , Nat Plants, 2016, Nov 21;2:16182 PMID: 27869786
- Pladienolide B is the major analogue of a family of macrocyclic lactones isolated from Streptomyces platensis. Pladienolide B is a highly potent inhibitor of both hypoxia signals and cancer cell proliferation. Pladienolide B binds to SF3b complex blocking the spliceosome.
- Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA.
- Arfaoui A, .et al. , EMBO Mol Med, 2019, Oct;11(10):e9930 PMID: 31476112
- KE Mengwasser, .et al. , Mol Cell, 2019, S1097-2765(18)31062-1 PMID: 30686591
- Sahar AlShareef, .et al. , BMC Genomics, 2017, 18: 260 PMID: 28347276
- Ling Y, .et al. , Plant J, 2017, Jan;89(2):291-309 PMID: 27664942
- Matthew J. Hangauer, .et al. , Nature, 2017, Nov 9; 551(7679): 247-250 PMID: 29088702
- Ji Hyun Kim, .et al. , Animal Cells and Systems, 2017, 21:1, 17-22 PMID: 30460047
- M Tanikawa, .et al. , Oncogenesis, 2016, Dec; 5(12): e280 PMID: 27991914
- Ji Hyun Kim, .et al. , Biochim Biophys Acta, 2016, Jun; 1863(6 Pt A): 1307-1318 PMID: 27033521
- FR901464 is a potent anticancer natural product that lowers the mRNA levels of oncogenes and tumor suppressor genes.
- Hiroaki Ohara, .et al. , Mol Ther Nucleic Acids, 2023, Jul 17;33:404-412 PMID: 37547287