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  1. Aspartame is a methyl ester of the dipeptide of the natural amino acids L-aspartic acid and L-phenylalanine. Under strongly acidic or alkaline conditions, aspartame may generate methanol by hydrolysis.
  2. Chemically, idebenone is an organic compound of the quinone family. It is also promoted commercially as a synthetic analog of coenzyme Q10 (CoQ10).
  3. Pramiracetam is a nootropic drug derived from piracetam.
  4. Naltrexone is an opioid receptor antagonist used primarily in the management of alcohol dependence and opioid dependence.
  5. Heparin, also known as unfractionated heparin, a highly sulfated glycosaminoglycan, is widely used as an injectable anticoagulant, and has the highest negative charge density of any known biological molecule.
  6. Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity.
  7. Atracurium besylate is a neuromuscular blocking agent with ED95 of 0.2 mg/kg.
  8. Amidopyrine is white crystalline substance used as an analgesic and antipyretic.
  9. Azacyclonol, also known as γ-pipradol, is a drug used to diminish hallucinations in psychotic individuals.
  10. Articaine is a dental local anesthetic which contains an additional ester group that is metabolized by estearases in blood and tissue.
  11. Altrenogest is a progestogen structurally related to veterinary steroid trenbolone.
  12. MCP inhibitor

    Bindarit is an anti-inflammatory small molecule that modulates the NFκB pathway.
  13. ENOblock (AP-III-a4) is a novel small molecule which is the first, nonsubstrate analogue that directly binds to enolase and inhibits its activity (IC50=0.576 uM); inhibit cancer cell metastasis in vivo.
  14. Fenticonazole nitrate is an azole antifungal agent.
  15. Ibandronate sodium is a highly potent nitrogen-containing bisphosphonate used for the treatment of osteoporosis.
  16. Levosimendan is a Ca2+ sensitizer that increases contractile force of the myocardium by enhancing the sensitivity of myofilaments to calcium without increasing intracellular calcium concentration.
  17. Iopromide is a nonionic, injectable radio-contrast medium.
  18. Nadifloxacin is a cell-permeable, synthetic, broad-spectrum fluoroquinolone antibiotic that inhibits the growth of both gram-positive and gram-negative microbes.
  19. Paroxetine is an antidepressant drug of the SSRI type.
  20. Pyridoxine hydrochloride is a form of vitamin B6.
  21. Pidotimod is an immunostimulant.
  22. Moxalactam is a synthetically derived, structurally unique beta-lactam antibiotic. Its antimicrobial activity encompasses a wide spectrum and includes some strains of pseudomonal species.
  23. Guanosine is a purine nucleoside comprising guanine attached to a ribose (ribofuranose) ring via a β-N9-glycosidic bond.
  24. Carnosic acid is a diterpene compound exhibiting antioxidative, anticancer, anti-angiogenic, anti-inflammatory, anti-metabolic disorder, and hepatoprotective and neuroprotective activities.
  25. (2-Hydroxypropyl)-β-cyclodextrin is a widely used drug delivery vehicle to improve the stability and bioavailability.
  26. GR antagonist

    AL082D06 is a nonsteroidal glucocorticoid receptor antagonist.
  27. Butylphthalide is an antioxidant and one of the chemical constituents in celery oil, along with sedanolide, which is primarily responsible for the aroma and taste of celery.
  28. Mad2 inhibitor

    M2I-1 is a Mad2 inhibitor targeting the binding of Mad2 to Cdc20, an essential protein-protein interaction (PPI) within the spindle assembly checkpoint (SAC).
  29. Dimethyl 4-hydroxyisophthalate is a methyl salicylate analogue.
  30. Docosahexaenoic Acid methyl ester is a methylated docosahexaenoic acid analog which can be intercalated into membrane phospholipids without being oxidized or hydrolyzed.
  31. Efaproxiral increases oxygen levels in hypoxic tumor tissues by binding non-covalently to the hemoglobin tetramer and decreasing hemoglobin-oxygen binding affinity.
  32. Visual cycle isomerase inhibitor

    Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro.
  33. nipradilol is an alpha(1),beta-blocker with a nitric oxide donative action
  34. Halofuginone is a semisynthetic quinazolinone alkaloid anticoccidial derived from the plant Dichroa febrifuga, with antifibrotic and potential antineoplastic activities.
  35. definitive endoderm formation inducer

    IDE1 is a potent cell-permeable definitive endoderm formation inducer (EC50 = 125 nM, ESC) similar to IDE 2.
  36. fast-skeletal-troponin activator

    Tirasemtiv amplifies skeletal muscle response to nerve activation in humans.
  37. Menaquinone-7 (Vitamin K2-7), belongs to a class of K2-vitamin homologs, is originally discovered as the anti-hemorrhagic factors.
  38. Pyronaridine Tetraphosphate is a common antimalarial agent that has been found to enhance the antitumor activity of doxorubicin against multidrug-resistant cancers K562/A02 and MCF-7/ADR.
  39. Vancomycin is a glycopeptide antibiotic used in the prophylaxis and treatment of infections caused by Gram-positive bacteria
  40. synthesized plant gowth regulator

    Prohydrojasmon racemate is a synthesized plant gowth regulator.
  41. Tirapazamine is a bioreductive, anti-neoplastic, anti-cancer agent that is selectively toxic to cells under hypoxic conditions.
  42. Cyclamic acid is one of the most widely used artificial sweeteners.
  43. Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue.
  44. Histone-H2A peptide

    Histone H2A is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells.
  45. Sapacitabine is an orally bioavailable pyrimidine analogue prodrug with potential antineoplastic activity.
  46. Ravuconazole is an ergosterol biosynthesis inhibitor and antifungal agen
  47. Doripenem is a compound used as an antibacterial agent.
  48. D2PM (hydrochloride) is a psychoactive designer drug that has recently been demonstrated to have toxic effects in humans.
  49. O-GlcNAcase inhibitor

    Thiamet G is a potent, selective O-GlcNAcase inhibitor with Kiof 21 nM, while exhibiting 37,000-fold selectivity over human lysosomal-hexosaminidase.

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