Catalog No.Inhibitor Name Dehydrogenase
A10613Mycophenolate Mofetil
A12899PluriSIn #1 (NSC 14613)
A10070Ammonium Glycyrrhizinate
A14795Gossypol Acetate

1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

27 Item(s)

per page

Set Descending Direction
  1. MF-438

    Catalog No. A20963
    Quick View
    SCD1 inhibitor
    MF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1. Learn More
  2. CVT-12012

    Catalog No. A21447
    Quick View
    SCD inhibitor
    CVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively. Learn More
  3. A939572

    Catalog No. A13298
    Quick View
    SCD1 inhibitor
    A939572 is a potent, and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. Learn More
  4. CAY10566

    Catalog No. A16936
    Quick View
    SCD1 inhibitor
    CAY10566 is a potent and selective inhibitor of SCD1 that demonstrates IC50 values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. Learn More
  5. Vidofludimus (4SC-101)

    Catalog No. A12997
    Quick View
    DHODH inhibitor
    Vidofludimus is a novel orally active and potent DHODH inhibitor. Learn More
  6. CBR 5884

    Catalog No. A16176
    Quick View
    PHGDH inhibitor
    CBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM. Learn More
  7. Fomepizole

    Catalog No. A16164
    Quick View
    alcohol dehydrogenase inhibitor
    Fomepizole is an alcohol dehydrogenase inhibitor used for the treatment of ethylene glycol and methanol poisonings in adults. Learn More
  8. Trilostane

    Catalog No. A10949
    Quick View
    Trilostane is an inhibitor of 3??-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. Learn More
  9. AG-120

    Catalog No. A15869
    Quick View
    Dehydrogenase Inhibitor
    AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Learn More
  10. NCT-501

    Catalog No. A15892
    Quick View
    hALDH1 Inhibitor‎
    NCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. Learn More
  11. Alda 1

    Catalog No. A15805
    Quick View
    ALDH2 Activator
    Alda 1 is an activator of aldehyde dehydrogenase 2 (ALDH2). Learn More
  12. MK-8245 Trifluoroacetate

    Catalog No. A15170
    Quick View
    Liver-targeting SCD Inhibitor‎
    MK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Learn More
  13. Monoammoniumglycyrrhizinate

    Catalog No. A14599
    Quick View
    Monoammoniumglycyrrhizinate is a constituent of the licorice root that has vital anti-viral activities that have been shown to inhibit the expression of 11_?HSD2 (11_?hydroxysteroid dehydrogenase type 2) via an indirect mechanism. Learn More
  14. AZD4017

    Catalog No. A13542
    Quick View
    HSD1 inhibitor
    AZD4017 is a potent, selective, and orally bioavailable11b-HSD1 inhibitor (11b-hydroxysteroid dehydrogenase type 1 inhibitor). Learn More
  15. Ammonium Glycyrrhizinate (AMGZ)

    Catalog No. A10070
    Quick View
    Dehydrogenase inhibitor
    Mono-ammonium glycyrrhizinate(AMGZ) is a unique product derived from Licorice root and has an extremely sweet taste. Learn More
  16. ASP9521

    Catalog No. A14412
    Quick View
    ASP9521 is a novel, selective, orally bioavailable inhibitor of 17??-hydroxysteroid dehydrogenase type 5 (17bHSD5, AKR1C3). Learn More
  17. CGP 3466B maleate

    Catalog No. A12385
    GAPDH inhibitor
    CGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. Learn More
  18. Brequinar

    Catalog No. A12442
    Quick View
    Dihydroorotate Dehydrogenase Inhibitor
    Brequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. Learn More
  19. Disulfiram

    Catalog No. A10320
    Quick View
    Disulfiram blocks the processing of alcohol in the body by inhibiting acetaldehyde dehydrogenase thus causing an unpleasant reaction when alcohol is consumed. Learn More
  20. Ranolazine

    Catalog No. A10780
    Quick View
    Ranolazine is a partial fatty acid oxidation inhibitor, shifts ATP production from fatty acid to more oxygen-efficient carbohydrate oxidation. Learn More
  21. CPI-613 (Devimistat)

    Catalog No. A11786
    Quick View
    Dehydrogenase Inhibitor
    CPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Learn More
  22. Gimeracil

    Catalog No. A11682
    Quick View
    Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination. Learn More
  23. Leflunomide

    Catalog No. A10521
    Quick View
    Dehydrogenase inhibitor
    Leflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain. Learn More
  24. Gossypol

    Catalog No. A10435
    Quick View
    dehydrogenase inhibitor
    Gossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. Learn More
  25. Mycophenolate mofetil (CellCept)

    Catalog No. A10613
    Quick View
    IMPDH inhibitor
    Mycophenolate mofetil is a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) in purine biosynthesis (specifically guanine synthesis) which is necessary for the growth of T cells and B cells. Learn More
  26. Celastrol

    Catalog No. A10192
    Quick View

    Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.

    Learn More
  27. MK-8245

    Catalog No. A11403
    Quick View
    SCD inhibitor
    MK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia. Learn More

27 Item(s)

per page

Set Descending Direction