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$0.00 Dehydrogenases
| Catalog No. | Inhibitor Name | Dehydrogenase |
|---|---|---|
| A10613 | Mycophenolate Mofetil | *** |
| A12902 | AGI-5198 | ** |
| A11403 | MK-8245 | **** |
| A15892 | NCT-501 | ** |
| A15798 | SW033291 | **** |
| A12997 | Vidofludimus | * |
| A12903 | AGI-6780 | *** |
| A11786 | CPI-613 | |
| A10521 | Leflunomide | |
| A10320 | Disulfiram | |
| A10949 | Trilostane | |
| A12899 | PluriSIn #1 (NSC 14613) | |
| A10070 | Ammonium Glycyrrhizinate | |
| A11682 | Gimeracil | |
| A14795 | Gossypol Acetate | |
| A10353 | Enoxolone | |
| A10348 | Emodin |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
27 Item(s)
per page
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MF-438
Catalog No. A20963 SCD1 inhibitorMF-438 is a potent and orally bioavailable stearoyl-CoA desaturase 1 (SCD1) inhibitor with an EC50 of 2.3 nM for rSCD1. Learn More -
CVT-12012
Catalog No. A21447 SCD inhibitorCVT-12012 is a potent and orally bioavailable stearoyl-coA desaturase (SCD) inhibitor, with IC50s of 38 nM, 6.1 nM for rat microsomal and human HEPG2, respectively. Learn More -
A939572
Catalog No. A13298 SCD1 inhibitorA939572 is a potent, and orally bioavailable stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50 values of <4 nM and 37 nM for mSCD1 and hSCD1, respectively. Learn More -
CAY10566
Catalog No. A16936 SCD1 inhibitorCAY10566 is a potent and selective inhibitor of SCD1 that demonstrates IC50 values of 4.5 and 26 nM in mouse and human enzymatic assays, respectively. Learn More -
Vidofludimus (4SC-101)
Catalog No. A12997 DHODH inhibitorVidofludimus is a novel orally active and potent DHODH inhibitor. Learn More -
CBR 5884
Catalog No. A16176 PHGDH inhibitorCBR 5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH), inhibiting serine synthesis from 3-phosphoglycerate in cells with an IC50 value of 33 uM. Learn More -
Fomepizole
Catalog No. A16164 alcohol dehydrogenase inhibitorFomepizole is an alcohol dehydrogenase inhibitor used for the treatment of ethylene glycol and methanol poisonings in adults. Learn More -
Trilostane
Catalog No. A10949 Trilostane is an inhibitor of 3??-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome. Learn More -
AG-120
Catalog No. A15869 Dehydrogenase InhibitorAG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Learn More -
NCT-501
Catalog No. A15892 hALDH1 InhibitorNCT-501 is a potent and selective inhibitor of Aldehyde Dehydrogenase 1A1 (ALDH1A1) with IC50 of 40 nM. Learn More -
Alda 1
Catalog No. A15805 -
MK-8245 Trifluoroacetate
Catalog No. A15170 Liver-targeting SCD InhibitorMK-8245 trifluoroacetate is a liver-targeting inhibitor of stearoyl-CoA desaturase (SCD) with IC50 of 1 nM for human SCD1 and 3 nM for both rat SCD1 and mouse SCD1, with anti-diabetic and anti-dyslipidemic efficacy. Learn More -
Monoammoniumglycyrrhizinate
Catalog No. A14599 Monoammoniumglycyrrhizinate is a constituent of the licorice root that has vital anti-viral activities that have been shown to inhibit the expression of 11_?HSD2 (11_?hydroxysteroid dehydrogenase type 2) via an indirect mechanism. Learn More -
AZD4017
Catalog No. A13542 HSD1 inhibitorAZD4017 is a potent, selective, and orally bioavailable11b-HSD1 inhibitor (11b-hydroxysteroid dehydrogenase type 1 inhibitor). Learn More -
Ammonium Glycyrrhizinate (AMGZ)
Catalog No. A10070 Dehydrogenase inhibitorMono-ammonium glycyrrhizinate(AMGZ) is a unique product derived from Licorice root and has an extremely sweet taste. Learn More -
ASP9521
Catalog No. A14412 ASP9521 is a novel, selective, orally bioavailable inhibitor of 17??-hydroxysteroid dehydrogenase type 5 (17bHSD5, AKR1C3). Learn More -
CGP 3466B maleate
Catalog No. A12385 GAPDH inhibitorCGP 3466B maleate is an orally active glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibitor. Learn More -
Brequinar
Catalog No. A12442 Dihydroorotate Dehydrogenase InhibitorBrequinar is an inhibitor of dihydroorotate dehydrogenase, an enzyme that is required for de novo pyrimidine biosynthesis. Learn More -
Disulfiram
Catalog No. A10320 Disulfiram blocks the processing of alcohol in the body by inhibiting acetaldehyde dehydrogenase thus causing an unpleasant reaction when alcohol is consumed. Learn More -
Ranolazine
Catalog No. A10780 Ranolazine is a partial fatty acid oxidation inhibitor, shifts ATP production from fatty acid to more oxygen-efficient carbohydrate oxidation. Learn More -
CPI-613 (Devimistat)
Catalog No. A11786 Dehydrogenase InhibitorCPI-613 is a racemic mixture of the enantiomers of a synthetic alpha-lipoic lipoic acid analogue with potential chemopreventive and antineoplastic activities. Learn More -
Gimeracil
Catalog No. A11682 Gimeracil, an inhibitor of dihydropyrimidine dehydrogenase, inhibits the early step in homologous recombination. Learn More -
Leflunomide
Catalog No. A10521 Dehydrogenase inhibitorLeflunomide is a pyrimidine synthesis inhibitor belonging to the DMARD (disease-modifying antirheumatic drug) class of drugs. Leflunomide is used to relieve symptoms caused by rheumatoid arthritis, such as inflammation, swelling, stiffness, and joint pain. Learn More -
Gossypol
Catalog No. A10435 dehydrogenase inhibitorGossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. Learn More -
Mycophenolate mofetil (CellCept)
Catalog No. A10613 IMPDH inhibitorMycophenolate mofetil is a reversible inhibitor of inosine monophosphate dehydrogenase (IMPDH) in purine biosynthesis (specifically guanine synthesis) which is necessary for the growth of T cells and B cells. Learn More -
Celastrol
Catalog No. A10192 Celastrol is a triterpenoid antioxidant compound isolated from the Chinese Thunder of God vine (T. wilfordii). In an isolated rat liver assay of lipid peroxidation, celastrol had an IC50 value of 7 µM, equivalent to about 15 times the antioxidant potency of α-tocopherol.
Learn More -
MK-8245
Catalog No. A11403 SCD inhibitorMK-8245 is a Liver-Targeted Stearoyl-CoA Desaturase (SCD) Inhibitor. MK-8245 is useful for the Treatment of Diabetes and Dyslipidemia. Learn More
27 Item(s)
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