MMP

Catalog No.Inhibitor Name MMP
A12985Batimastat (BB-94)
***
A13320Ilomastat (GM6001, Galardin)
****
A14253SB-3CT
*
A12826Marimastat (BB-2516)
***
A13072NSC 405020
A10651Nobiletin

Notes:
1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

26 Item(s)

per page

Set Descending Direction
  1. CP 471474

    Catalog No. A15297
    Quick View
    MMP inhibitor
    CP 471474, broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively). Learn More
  2. ARP 100

    Catalog No. A15292
    Quick View
    MMP-2 inhibitor
    ARP 100 is a selective inhibitor of matrix metalloproteinases 2 (MMP-2) with IC50 value of 12 nM. Learn More
  3. ARP 101

    Catalog No. A15293
    Quick View
    MMP-2 inhibitor
    ARP 101, selective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1 (IC50 values are 0.81 and 486 nM respectively). Learn More
  4. Batimastat sodium salt

    Catalog No. A15326
    Quick View
    MMP Inhibitor
    Batimastat is an anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. Learn More
  5. ONO 4817

    Catalog No. A15305
    Quick View
    Broad spectrum MMP inhibitor
    ONO 4817 is used for testing effective treatment of MMP-related diseases. Learn More
  6. PD 166793

    Catalog No. A15307
    Quick View
    Broad spectrum MMP inhibitor
    PD166793 is a cell-permeable compound that strongly inhibits MMP (matrix metalloproteinase) -2 , -3, and -13, and weakly inhibits AMP deaminase, MMP-1, -7, -9, and -14. Learn More
  7. Ro 32-3555

    Catalog No. A15311
    MMP inhibitor
    Ro 32-3555 is a potent, collagenase-selective MMP inhibitor . Learn More
  8. UK 370106

    Catalog No. A15316
    Quick View
    MMP-3/MMP-12 Inhiibitor
    UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor . Learn More
  9. WAY 170523

    Catalog No. A15317
    Quick View
    MMP-13 inhibitor
    WAY 170523 has been reported to be a selective and potent inhibitor of MMP-13. Learn More
  10. 20(R)-Ginsenoside Rh2

    Catalog No. A15408
    Quick View
    MMP Inhibitor
    20(R)-Ginsenoside Rh2 is a matrix metalloproteinase (MMP) inhibitor that acts as a cell antiproliferator. Learn More
  11. CL-82198

    Catalog No. A13597
    Quick View
    MMP-13 inhibitor
    CL-82198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13), producing 89% inhibition at 10 mg/ml. Learn More
  12. 4-epi-Chlortetracycline Hydrochloride

    Catalog No. A12848
    Quick View
    MMP inhibitor
    4-epi-Chlortetracycline Hydrochloride is a tetracycline derivative that acts as a metalloproteinase (MMP) inhibitor, used in treating tissue destructive diseases and cancer Learn More
  13. NSC 405020

    Catalog No. A13072
    Quick View
    MT1-MMP inhibitor
    NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L). Learn More
  14. Marimastat

    Catalog No. A12826
    Quick View
    MMP inhibitor
    Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor. Learn More
  15. GM 6001

    Catalog No. A13320
    Quick View
    MMP inhibitor
    GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs). Learn More
  16. SB-3CT

    Catalog No. A14253
    Quick View
    MMP-2/MMP-9 inhibitor
    SB-3CT is an effective and selective gelatinase inhibitor with Ki of 13.9 nM and 600 nM for MMP-2 and MMP-9. Learn More
  17. UK 356618

    Catalog No. A15323
    Quick View
    MMP-3 inhibitor
    UK 356618 is a selective and potent inhibitor of MMP-3 that shows selectivity over a range of MMPs. Learn More
  18. Doxycycline HCl

    Catalog No. A10745
    Quick View
    Doxycycline Hydrochloride is a synthetic tetracycline derivative with similar antimicrobial activity. Learn More
  19. DC_AC50

    Catalog No. A16043
    Quick View
    Atox1/CCS inhibitor
    DC_AC50 is an inhibitor of copper trafficking proteins Atox1 and CCS, resulting in a disruption of cellular copper transport. Learn More
  20. Abametapir

    Catalog No. A15945
    Quick View
    metalloproteinase inhibitor
    Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice. Learn More
  21. CTS-1027

    Catalog No. A11345
    Quick View
    Matrix Metalloproteinase Inhibitor
    CTS-1027 is a potent MMP inhibitor that protects Against TNFα- and α-Fas-Induced liver Injury. Learn More
  22. TAPI-2

    Catalog No. A14009
    Quick View
    TACE/MMP inhibitor
    TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture. Learn More
  23. TAPI-0

    Catalog No. A13724
    Quick View
    TACE/MMP inhibitor
    TAPI-0 is an inhibitor of TACE (IC50 = 50-100 nM) as well as other matrix and membrane metalloproteases Learn More
  24. TAPI-1

    Catalog No. A14070
    Quick View
    TACE/MMP inhibitor
  25. Batimastat (BB-94)

    Catalog No. A12985
    Quick View
    MMP inhibitor
    Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively. Learn More
  26. TMI-1

    Catalog No. A17212
    Quick View
    TACE/MMP inhibitor
    TMI-1 is a novel orally active dual inhibitor of ADAM17 (TACE) and MMP. Learn More

26 Item(s)

per page

Set Descending Direction
Rewards