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Inhibitory Selectivity
Catalog No.Inhibitor Name MMP
A12985Batimastat (BB-94)
A13320Ilomastat (GM6001, Galardin)
A12826Marimastat (BB-2516)
A13072NSC 405020

1.Hover mouse over " * " to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of " * " is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

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Catalog No. Product Name Application Product Information

CP 471474

MMP inhibitor
CP 471474, broad spectrum MMP inhibitor (IC50 values are 0.7, 0.9, 13, 16 and 1170 nM for MMP-2, MMP-13, MMP-9, MMP-3 and MMP-1 respectively).

UK 370106

MMP-3/MMP-12 Inhiibitor
UK 370106 is a highly selective MMP-3 and MMP-12 inhibitor .

Ro 32-3555

MMP inhibitor
Ro 32-3555 is a potent, collagenase-selective MMP inhibitor .

PD 166793

Broad spectrum MMP inhibitor
PD166793 is a cell-permeable compound that strongly inhibits MMP (matrix metalloproteinase) -2 , -3, and -13, and weakly inhibits AMP deaminase, MMP-1, -7, -9, and -14.

ONO 4817

Broad spectrum MMP inhibitor
ONO 4817 is used for testing effective treatment of MMP-related diseases.

UK 356618

MMP-3 inhibitor
UK 356618 is a selective and potent inhibitor of MMP-3 that shows selectivity over a range of MMPs.

ARP 101

MMP-2 inhibitor
ARP 101, selective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1 (IC50 values are 0.81 and 486 nM respectively).

ARP 100

MMP-2 inhibitor
ARP 100 is a selective inhibitor of matrix metalloproteinases 2 (MMP-2) with IC50 value of 12 nM.
A15326 SALE

Batimastat sodium salt

MMP Inhibitor
Batimastat is an anticancer drug that belongs to the family of drugs called angiogenesis inhibitors. Batimastat (BB-94) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor.


MMP-13 inhibitor
CL-82198 is a selective inhibitor of human collagenase-3, also known as matrix metalloproteinase-13 (MMP-13), producing 89% inhibition at 10 mg/ml.

20(R)-Ginsenoside Rh2

MMP Inhibitor
20(R)-Ginsenoside Rh2 is a matrix metalloproteinase (MMP) inhibitor that acts as a cell antiproliferator.


MMP-2/MMP-9 inhibitor
SB-3CT is an effective and selective gelatinase inhibitor with Ki of 13.9 nM and 600 nM for MMP-2 and MMP-9.
A13320 SALE

GM 6001

MMP inhibitor
GM 6001 is a potent, reversible broad spectrum inhibitor of zinc-containing proteases, including matrix metalloproteinases (MMPs).
A12826 SALE


MMP inhibitor
Marimastat acted as a broad-spectrum matrix metalloproteinase inhibitor.
A13072 SALE

NSC 405020

MT1-MMP inhibitor
NSC-405020 is a membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor (IC50 > 100 μmol/L).

4-epi-Chlortetracycline Hydrochloride

MMP inhibitor
4-epi-Chlortetracycline Hydrochloride is a tetracycline derivative that acts as a metalloproteinase (MMP) inhibitor, used in treating tissue destructive diseases and cancer

WAY 170523

MMP-13 inhibitor
WAY 170523 has been reported to be a selective and potent inhibitor of MMP-13.
A15945 SALE


metalloproteinase inhibitor
Abametapir is the active ingredient of Xeglyze Lotion. Abametapir inhibits metalloproteinases; enzymes that are essential to physiological processes critical for egg development and the survival of nymph and adult lice.

Doxycycline HCl

Doxycycline Hydrochloride is a synthetic tetracycline derivative with similar antimicrobial activity.

GI 254023X

ADAM10 metalloprotease inhibitor
GI 254023X is a selective ADAM10 metalloprotease inhibitor; displays over 100-fold higher potency at ADAM10 compared to ADAM17.


Matrix Metalloproteinase Inhibitor
CTS-1027 is a potent MMP inhibitor that protects Against TNFα- and α-Fas-Induced liver Injury.


TACE/MMP inhibitor
TAPI-2 is an inhibitor of TACE, ADAMs, ACE secretase, and other MMPs (metalloproteinases). TAPI-2 blocks release of DCC7, APP, TNFα, L-selectin, NOTCH, TGFα, IL-6R9, erbB2/HER2, and ACE. This inhibitor has been used in tissue culture.


TACE/MMP inhibitor
TAPI-0 is an inhibitor of TACE (IC50 = 50-100 nM) as well as other matrix and membrane metalloproteases


TACE/MMP inhibitor
A12985 SALE

Batimastat (BB-94)

MMP inhibitor
Batimastat (BB-94) is a potent and synthetic inhibitor of a broad spectrum of matrix metalloproteinases (MMPs), including interstitial collagenase (IC50 = 3 nM), stromelysin (IC50 = 20 nM), Mr 72,000 type IV collagenase (IC50 = 4 nM), Mr 92,000 type IV collagenase (IC50 = 4 nM), and matrilysin (IC50 = 6 nM). It is a low-molecular-weight (MW = 478) and peptide-like collagen substrate analogue consisting of a peptide backbone and a hydroxamic acid group which bind to MMPs and the catalytically active zinc atom respectively.


Atox1/CCS inhibitor
DC_AC50 is an inhibitor of copper trafficking proteins Atox1 and CCS, resulting in a disruption of cellular copper transport.

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