SRC

Actions
  1. Activator (1)
  2. Inhibitor (25)
  3. Stimulator (1)


Items 1 to 25 of 28 total

per page
Page:
  1. 1
  2. 2

Set Descending Direction
Catalog No. Product Name Product Information
A13232

1-NA-PP1

1-NA-PP1 is a selective inhibitor of v-Src and c-Fyn as well as c-Abl
A13290

A-419259

A-419259 is an inhibitor of Src family kinases (SFK) (IC50 = 0.1 - 0.3 uM).
A11288

A-770041

A-770041 is selective and orally active Src-family Lck inhibitor; A-770041 is a 147 nM inhibitor of Lck (1 mM ATP) and is 300-fold selective against Fyn, the other Src family kinase involved in T-cell signaling.
A14323

A419259

A419259 trihydrochloride is an apoptosis inducing agent that inhibits Src family kinases (c-Src).
A16241

AZM475271

AZM475271 is a potent and selective Src kinase inhibitor with IC50 of 5 nM; no inhibitory activity on Flt3, KDR, Tie-2.
A10161

Bosutinib (SKI-606)

Bosutinib (SKI-606) is a tyrosine kinase inhibitor undergoing research for use in the treatment of cancer.
A13821

CGP77675

CGP77675 is a potent Src kinase inhibitor. CGP77675 inhibited phosphorylation of peptide substrates and autophosphorylation of purified Src (IC50: 5-20 and 40 nM, respectively).
A10290

Dasatinib (BMS-354825)

Dasatinib (BMS-354825) is an oral multi- BCR/ABL and Src family tyrosine kinase inhibitor. The main targets of dasatinib, are BCR/ABL, Src, c-Kit, ephrin receptors, and several other tyrosine kinases, but not erbB kinases such as EGFR or Her2.
A15060

Dasatinib hydrochloride

Dasatinib hydrochloride is a potent and dual Abl/ Src inhibitor IC50 of ??1 nM/0.8 nM respectively; also inhibit c-Kit (WT)/c-Kit (D816V) with IC50 of 79 nM/37 nM.
A12214

KX1-004

KX1-004 is a potent small molecule inhibitor of Src-PTK as a potential protective drug for NIHL.
A11177

KX2-391

KX2-391 is a novel non-ATP competitive substrate-pocket directed SRC inhibitor.

A11471

KX2-391 2HCl

KX2-391 2Hcl is the first clinical Src inhibitor (peptidomimetic class) that targets the peptide substrate site of Src, with GI50 of 9-60 nM in cancer cell lines.
A13415

MCB-613

MCB-613 is a potent, pan steroid receptor coactivator (SRC) stimulator.
A12417

MLR 1023

MLR 1023 is a selective allosteric activator of Lyn kinase (EC50 = 63 nM)
A16240

MNS

MNS is a potent and selective inhibitor of Src and Syk tyrosine kinases.
A11020

PCI-32765

PCI-32765 is an orally bioavailable small-molecule inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity.
A13868

PD-166285

PD 166285 is a potent inhibitor of the tyrosine kinases c-Src, Flg (fibroblast growth factor receptor 1, FGFR1).
A12724

PP1

PP1 is a potent inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 5 and 6 nM respectively). Displays > 8000-fold selectivity over ZAP-70 and JAK2. Also moderately inhibits p38, CSK, PDGF receptors, RET-derived oncoproteins, c-Kit and Bcr-Abl
A13573

PP1 Analog II, 1NM-PP1

PP1 Analog II, 1NM-PP1 is a cell-permeable PP1 analog that acts as a potent and selective inhibitor of mutant kinases over their wild-type progenitors.
A12723

PP2

PP2 is a selective inhibitor of Src-family tyrosine kinases. Inhibits p56lck and p59fynT (IC50 values are 4 and 5 nM respectively). Displays > 10000-fold selectivity over ZAP-70 and JAK2. Moderately inhibits CSK (IC50 = 0.73 μM).
A10108

Saracatinib (AZD0530)

Saracatinib (AZD0530) is a highly selective, orally available, dual-specific Src/Abl kinase inhibitor with IC50 of 2.7 and 30 nM for c-Src and Abl kinase, respectively.
A15518

SU6656

SU6656 is a selective inhibitor of Src kinases, Including Src, Yes, Lyn, and Fyn (IC50 = 280, 20, 130, 170 nM, respectively).
A16243

T338C Src-IN-1

T338C Src-IN-1 is a potent mutant-Src T338C inhibitor; exhibited the most potent inhibition of T338C(IC50=111 nM) relative to WT c-Src (10-fold increase).
A16244

T338C Src-IN-2

T338C Src-IN-2 is a potent mutant c-Src T338C kinase inhibitor with IC50 of 317 nM; also inhibits T338C/V323A and T338C/V323S with IC50 of 57 nM/19 nM.
A13820

TG 100572

TG 100572 is VEGFR2 and Src kinase inhibitor.

Items 1 to 25 of 28 total

per page
Page:
  1. 1
  2. 2

Set Descending Direction