Items 1 to 25 of 26 total

per page
  1. 1
  2. 2

Set Descending Direction
Catalog No. Product Name Application Product Information
A11997 SALE


(S)-10-Hydroxycamptothecin is a camptothecin derivative that inhibits DNA topoisomerase by enacting strand breaks in chromosomal DNA and inducing apoptosis.
A10041 SALE


topoisomerase II inhibitor

Adriamycin is an anthracycline antibiotic, it works by intercalating DNA, while most serious adverse effect being life-threatening heart damage. It is commonly used in the treatment of a wide range of cancers, including hematological malignancies, many types of carcinoma, and soft tissue sarcomas.

A10071 SALE

Amonafide (AS1413)

Topoisomerase inhibitor

Amonafide is a DNA intercalator and topoisomerase II inhibitor for the treatment of neoplastic diseases, one of Antitumor agent.



topoisomerase II inhibitor
Amrubicin is a synthetic anthracycline antibiotic. It inhibits DNA topoisomerase II. Antineoplastic.
A13059 SALE


Beta-Lapachone is a selective DNA topoisomerase I inhibitor, exhibiting no inhibitory activities against DNA topoisomerase II or ligase.
A10174 SALE


Topoisomerase I inhibitor
Camptothecin is a cytotoxic quinoline alkaloid which inhibits the DNA enzyme topoisomerase I (topo I).
A10194 SALE

Cerubidine (Daunorubicin HCl, Rubidomycin HCl)


Cerubidine (Daunorubicin HCl, Rubidomycin HCl) interacts with DNA by intercalation and inhibition of macromolecular biosynthesis. This inhibits the progression of the enzyme topoisomerase II, which relaxes supercoils in DNA for transcription. It stabilizes the topoisomerase II complex after it has broken the DNA chain for replication, preventing the DNA double helix from being resealed and thereby stopping the process of replication.

A10345 SALE

Epirubicin HCl

Epirubicin is a cell-permeable anthracycline antitumor antibiotic. It is a stereoisomer(4′-epi-isomer) of doxorubicin that exhibits reduced cardiotoxicity. It is used to inhibit topoisomerase II and DNA helicase activity.
A10373 SALE

Etoposide (VP-16)

topoisomerase II inhibitor
Etoposide forms a ternary complex with DNA and the topoisomerase II enzyme (which aids in DNA unwinding), prevents re-ligation of the DNA strands, and by doing so causes DNA strands to break. Therefore, this causes errors in DNA synthesis and promotes apoptosis of the cancer cell.

Exatecan mesylate

topoisomerase I-inhibitor
Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death.


Flumequine is a synthetic chemotherapeutic antibiotic which affecting mammalian chromosome and DNA unwinding at the level of gyrase/topoisomerases.

Idarubicin HCl

Topoisomerase inhibitor
Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.
A10477 SALE

Irbesartan (Avapro)

AT1 antagonist
Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension.
A10478 SALE


Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1.
A10479 SALE

Irinotecan HCl Trihydrate (Campto)

Topoisomerase inhibitor
Irinotecan (CPT 11), a compound within the camptothecin family, is an inhibitor of topoisomerase 1 involved in cellular DNA replication and transcription.
A10557 SALE


Topoisomerase inhibitor
Marbofloxacin is a potent antibiotic of the 3rd generation fluoroquinolone group and acts by inhibiting bacterial DNA replication.

Mitoxantrone Hydrochloride

Mitoxantrone Dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating, and antineoplastic cytostatic anthraquinone derivative.
A10609 SALE

Moxifloxacin HCl

Topoisomerase inhibitor
Moxifloxacin is a quinolone/fluoroquinolone antibiotic.
A10652 SALE

Norfloxacin (Norxacin)

Topoisomerase inhibitor
Norfloxacin(Norxacin) is a broad-spectrum antibiotic.
A10666 SALE

Ofloxacin (DL8280)

Topoisomerase inhibitor
Ofloxacin is a synthetic broad-spectrum antimicrobial agent.
A11902 SALE

Pefloxacin mesylate

Pefloxacin mesylate is a synthetic chemotherapeutic agent and an antibacterial agent with IC5N/A of 6.7 nM.
A10735 SALE


Topoisomerase II inhibitor
Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication
A10740 SALE


Podophyllotoxin is a potent inhibitor of microtubule assembly that binds at the colchicine site of tubulin.
A12011 SALE

SN 38

DNA topoisomerase Inhibitor
SN 38 is the active metabolite of irinotecan (an analog of camptothecin - a topoisomerase I inhibitor).
A10939 SALE

Topotecan HCl (Hycamtin)

DNA topoisomerase I inhibitor
Topotecan HCl (Hycamtin) is a chemotherapeutic agent that is a topoisomerase inhibitor.

Items 1 to 25 of 26 total

per page
  1. 1
  2. 2

Set Descending Direction