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Heat Shock Proteins (HSP)

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  1. Inhibitor (23)


24 Item(s)

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Catalog No. Product Name Product Information
A10010

17-AAG (KOS953)

17-AAG is an ansamycin antibiotic which acts as an anti-tumor agent. Specifically, 17-AAG binds and inhibits Hsp90. Learn More
A10011

17-DMAG HCl (Alvespimycin)

17-DMAG is a water-soluble analog of 17-AAG and geldanamycin that binds the ATP binding site of Hsp90 and inhibits its chaperone activity. Displays more potent antitumor activity than 17-AAG. Learn More
A14990

Alvespimycin

Alvespimycin is a selective Hsp90 inhibitor with a GI50 of 53 nM. Learn More
A11062

AT13387

AT13387 is a targeted inhibitor of Hsp90,inhibiting its chaperone function and promoting the degradation of oncogenic signaling proteins involved in tumor cell proliferation and survival. Learn More
A10659

AUY922 (NVP-AUY922)

AUY922 (NVP-AUY922) is highly potent and oral inhibitor of Hsp90 with IC50=21 nM in Hsp90 FP binding assay and inhibits proliferation of various human cancer cell lines in vitro, with GI50 average 9 nM. Learn More
A10143

BIIB021

BIIB021 is an oral fully synthetic Hsp90 inhibitor that selectively and potently inhibits the molecular chaperone Hsp90 thereby inhibiting the proper assembly of multiple oncogenic proteins involved in tumor growth and survival. Learn More
A10178

Capsaicin

Capsaicin is an active component of chili peppers, which are plants belonging to the genus Capsicum. Learn More
A12648

CUDC-305 (DEBIO-0932 )

Debio 0932 is a novel heat shock protein 90 (HSP90) inhibitor with strong affinity for HSP90 alpha/beta, high oral bioavailability and potent anti-proliferative activity against a broad range of cancer cell lines (with a mean IC50 of 220 nmol/L), including many non-small cell lung cancer (NSCLC) cell lines which are resistant to standard-of-care (SOC) agents. Learn More
A11402

Ganetespib (STA-9090)

Ganetespib is a potent, synthetic, small molecule inhibitor of Hsp90, a chaperone protein that is essential to the function of certain other proteins that drive the growth, proliferation, and survival of many different types of cancer. Learn More
A11025

Geldanamycin

Geldanamycin binds to the ATP site of Hsp90 (Kd = 1.2 μM) and inhibits its chaperone activity. Learn More
A12850

HSP-990

HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (Hsp90) with potential antineoplastic activity. Learn More
A11272

IPI-493

IPI-493 is a potent and orally bioavailable HSP90 inhibitor with Ki of 21 nM. Learn More
A11269

IPI-504 (Retaspimycin HCl)

IPI-504 is a novel, water-soluble, potent inhibitor of heat-shock protein 90 (Hsp90). Learn More
A11195

KW-2478

KW-2478 is an agent that targets the human heat-shock protein 90 (Hsp90) with potential antineoplastic activity.

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A12388

MKT 077

Occupies mortalin-2 (mot-2), a member of the Hsp70 family, at its p53 binding site and enables p53 translocation to the nucleus. Selectively cytotoxic; causes growth arrest of cancer cells in culture. Also inhibits telomerase activity and cross-links F-actin. Learn More
A11131

MPC-3100

MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Learn More
A10660

NVP-BEP800

NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH2-terminal ATP-binding pocket of Hsp90. Learn More
A11074

PF-04929113 (SNX-5422)

PF-04929113 (SNX-5422) is orally bioavailable heat shock protein 90 (Hsp90) inhibitor. Learn More
A11130

PU-H71

PU-H71 is a potent Hsp90 inhibitor (IC50 = 50 nM). Learn More
A11768

Radicicol

Radicicol is a potent inhibitor of Hsp90, SRC, and Cox-2 Learn More
A11189

SNX-2112

SNX-2112 is a heat shock protein 90 (Hsp90) inhibitor with anticancer properties currently in clinical trials. SNX-2112 induced autophagy in a time- and dose-dependent manner via Akt/mTOR/p70S6K inhibition. SNX-2112 induces significant apoptosis and autophagy in human melanoma A-375 cells, and may be an effective targeted therapy agent

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A13351

VER 155008

VER 155008 is a small molecule, ATP-derivative inhibitor of HSP70 (IC50 = 500 nM). Learn More
A13817

VER-50589

VER-50589 is an isoxazole compound that inhibits Hsp90 with an IC50 value of 21 nM. Learn More
A11251

XL-888

XL888 is an orally bioavailable, ATP-competitive, small-molecule inhibitor of heat shock protein 90 (Hsp90) with potential antineoplastic activity. Learn More

24 Item(s)

per page

Set Descending Direction
Heat Shock Proteins (HSP)

Minimal Price: $40.00