Autophagy

13 Item(s)

per page

Set Descending Direction
  1. SMER28

    Catalog No. A15867
    Quick View
    Autophagy Activator
    SMER28 is a small-molecule enhancer (SMER) of autophagy, inducing autophagy independently of rapamycin in mammalian cells. Learn More
  2. Resveratrol

    Catalog No. A10785
    Quick View
    Resveratrol has a wide spectrum of targets including cyclooxygenases(i.e. COX, IC50=1.1 μM), lipooxygenases(LOX, IC50=2.7 μM), kinases, sirtuins and other proteins. It has anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. Learn More
  3. Azithromycin Dihydrate

    Catalog No. A16421
    Quick View
    Azithromycin Dihydrate is an acid stable orally administered macrolide antimicrobial drug, structurally related to erythromycin. Learn More
  4. Lys05

    Catalog No. A16358
    Quick View
    Autophagy inhibitor
    Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ. Learn More
  5. Scutellarein

    Catalog No. A12234
    Quick View
    Scutellarin, a main active ingredient extracted from Erigeron breviscapus (Vant.) Hand-Mazz, has been wildly used to treat acute cerebral infarction and paralysis induced by cerebrovascular diseases. Learn More
  6. MRT68921

    Catalog No. A15880
    Quick View
    Autophagy ULK1/2 inhibitor
    MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively. Learn More
  7. SBI-0206965

    Catalog No. A15795
    Quick View
    ULK1 inhibitor
    SBI-0206965 is a potent, selective and cell permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for the highly related kinase ULK2 . Learn More
  8. SBC-115076

    Catalog No. A15769
    Quick View
    PCSK9 antagonist
    SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) compounds, for the treatment and/or prevention of cardiovascular diseases. Learn More
  9. Spautin-1

    Catalog No. A12942
    Quick View
    Autophagy Inhibitor
    Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with IC50 of 1.03μM. In contrast, co-treatment with Spautin-1 increased IM-induced inhibition of cell viability with IC50 of 0.45 μM. Learn More
  10. Hydroxychloroquine Sulfate

    Catalog No. A14208
    Quick View
    Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Learn More
  11. Flubendazole (Flutelmium)

    Catalog No. A11656
    Quick View
    autophagy inducer
    Flubendazole is an anthelmintic used for protection against internal parasites and worms in dogs and cats. Learn More
  12. STF-62247

    Catalog No. A10866
    Quick View
    Autophagy Inducer
    STF-62247 is a small molecule agonist that induces autophagy and selectively causes lethality in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 nM). Learn More
  13. Chloroquine Phosphate

    Catalog No. A16445
    Quick View
    Chloroquine phosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent, also acting as an ATM activator. Learn More

13 Item(s)

per page

Set Descending Direction
Rewards