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c-MET



18 Item(s)

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Catalog No. Product Name Product Information
A10063

AMG 208

AMG 208 is a novel c-Met inhibitor that inhibits the ligand-dependent and ligand-independent activation of c-Met, inhibiting its tyrosine kinase activity. Learn More
A11055

AMG-458

AMG-458 is a potent inhibitor of c-Met with an IC50 value of 60nM and displays selectivity against VEGFR2. Learn More
A11087

ARQ 197

ARQ-197 is a selective inhibitor of the c-Met receptor tyrosine kinase Learn More
A10153

BMS-777607

BMS-777607 is a MET tyrosine kinase inhibitor that binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway. Learn More
A10154

BMS-794833

BMS-794833 is a potent ATP competitive inhibitor to Met and VEGFR-2 with IC50 of 1.7 and 15 nmol. Learn More
A11396

E-7050 (Golvatinib)

E7050 (also known as golvatinib is an orally bioavailable dual kinase inhibitor of c-Met (hepatocyte growth factor receptor) and VEGFR-2 (vascular endothelial growth factor receptor-2) tyrosine kinases with potential antineoplastic activity. Learn More
A11257

EMD-1214063

EMD-1214063 is an inhibitor of MET tyrosine kinase with potential antineoplastic activity. It binds to MET tyrosine kinase and disrupts MET signal transduction pathways, which may induce apoptosis in tumor cells overexpressing this kinase. Learn More
A10998

Foretinib (GSK1363089, XL880)

Foretinib (GSK1363089), a multikinase inhibitor of c-Met and VEGFR-2, blocks proliferation, induces Anoikis, and impairs ovarian cancer metastasis. Learn More
A11132

INCB28060

INCB28060, a novel inhibitor of c-MET kinase. INCB28060 exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10,000-fold selectivity over a large panel of human kinases. This inhibitor potently blocks c-MET phosphorylation and activation of its key downstream effectors in c-MET-dependent tumor cell lines. Learn More
A10493

JNJ-38877605

c-Met inhibitor JNJ-38877605 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. Learn More
A10587

MGCD-265

MGCD265 is a multitargeted tyrosine kinase inhibitor that binds to and inhibits the phosphorylation of several RTKs, including the c-Met receptor (HGFR); the Tek/Tie-2 receptor; VEGFR types 1, 2, and 3; and MST1R. Learn More
A11489

MK-8033

MK-8033 is a novel and specific dual ATP competitive c-Met/Ron inhibitor (IC50=1 nM Wt c-Met) under investigation as a treatment for cancer. Learn More
A10610

MP470 (MP-470)

MP470 is a c-Kit/PDGFR tyrosine kinase inhibitor. Learn More
A11150

NVP-BVU972

NVP-BVU972 is a selective MET inhibitor. Learn More
A10711

PF-04217903

PF-04217903 is a novel c-Met/hepatocyte growth factor receptor tyrosine kinase inhibitors. Learn More
A10713

PHA-665752

PHA665752 is a small-molecule inhibitor of c-Met/HGF/SF signaling. Learn More
A10839

SGX-523

SGX-523 is an orally bioavailable small molecule, specifically binds to c-Met protein, or HGFR, preventing binding of HGF and disrupting the MET signaling pathway. Learn More
A10869

SU11274

SU11274 is a Met tyrosine kinase inhibitor. Learn More

18 Item(s)

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c-MET

Minimal Price: $40.00